Farrell JJ - Search Results

1

HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.

McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperavičiūtė D, Carrington M, Sills GJ, Marson T, Jia X, de Bakker PI, Chinthapalli K, Molokhia M, Johnson MR, O'Connor GD, Chaila E, Alhusaini S, Shianna KV, Radtke RA, Heinzen EL, Walley N, Pandolfo M, Pichler W, Park BK, Depondt C, Sisodiya SM, Goldstein DB, Deloukas P, Delanty N, Cavalleri GL, Pirmohamed M. McCormack M, et al. Among authors: farrell jj. N Engl J Med. 2011 Mar 24;364(12):1134-43. doi: 10.1056/NEJMoa1013297. N Engl J Med. 2011. PMID: 21428769 Free PMC article.

2

Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation.

Naisbitt DJ, Farrell J, Gordon SF, Maggs JL, Burkhart C, Pichler WJ, Pirmohamed M, Park BK. Naisbitt DJ, et al. Mol Pharmacol. 2002 Sep;62(3):628-37. doi: 10.1124/mol.62.3.628. Mol Pharmacol. 2002. PMID: 12181439

3

Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones.

Naisbitt DJ, Britschgi M, Wong G, Farrell J, Depta JP, Chadwick DW, Pichler WJ, Pirmohamed M, Park BK. Naisbitt DJ, et al. Mol Pharmacol. 2003 Mar;63(3):732-41. doi: 10.1124/mol.63.3.732. Mol Pharmacol. 2003. PMID: 12606784

4

Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans.

Farrell J, Naisbitt DJ, Drummond NS, Depta JP, Vilar FJ, Pirmohamed M, Park BK. Farrell J, et al. J Pharmacol Exp Ther. 2003 Jul;306(1):229-37. doi: 10.1124/jpet.103.050112. Epub 2003 Apr 3. J Pharmacol Exp Ther. 2003. PMID: 12676884

5

Characterization of drug-specific T cells in lamotrigine hypersensitivity.

Naisbitt DJ, Farrell J, Wong G, Depta JP, Dodd CC, Hopkins JE, Gibney CA, Chadwick DW, Pichler WJ, Pirmohamed M, Park BK. Naisbitt DJ, et al. J Allergy Clin Immunol. 2003 Jun;111(6):1393-403. doi: 10.1067/mai.2003.1507. J Allergy Clin Immunol. 2003. PMID: 12789244

6

Characterization of the T-cell response in a patient with phenindione hypersensitivity.

Naisbitt DJ, Farrell J, Chamberlain PJ, Hopkins JE, Berry NG, Pirmohamed M, Park BK. Naisbitt DJ, et al. J Pharmacol Exp Ther. 2005 Jun;313(3):1058-65. doi: 10.1124/jpet.105.083758. Epub 2005 Mar 2. J Pharmacol Exp Ther. 2005. PMID: 15743920

7

Activation of T cells by carbamazepine and carbamazepine metabolites.

Wu Y, Sanderson JP, Farrell J, Drummond NS, Hanson A, Bowkett E, Berry N, Stachulski AV, Clarke SE, Pichler WJ, Pirmohamed M, Park BK, Naisbitt DJ. Wu Y, et al. J Allergy Clin Immunol. 2006 Jul;118(1):233-41. doi: 10.1016/j.jaci.2006.03.005. Epub 2006 Apr 27. J Allergy Clin Immunol. 2006. PMID: 16815161

8

Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity.

Wu Y, Farrell J, Pirmohamed M, Park BK, Naisbitt DJ. Wu Y, et al. J Allergy Clin Immunol. 2007 Apr;119(4):973-81. doi: 10.1016/j.jaci.2006.12.617. Epub 2007 Feb 22. J Allergy Clin Immunol. 2007. PMID: 17320939

9

Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.

Sanderson JP, Naisbitt DJ, Farrell J, Ashby CA, Tucker MJ, Rieder MJ, Pirmohamed M, Clarke SE, Park BK. Sanderson JP, et al. J Immunol. 2007 May 1;178(9):5533-42. doi: 10.4049/jimmunol.178.9.5533. J Immunol. 2007. PMID: 17442935

10

Trimethoprim stimulates T-cells through metabolism-dependent and -independent pathways.

El-Ghaiesh S, Sanderson JP, Farrell J, Lavergne SN, Syn WK, Pirmohamed M, Park BK, Naisbitt DJ. El-Ghaiesh S, et al. Chem Res Toxicol. 2011 Jun 20;24(6):791-3. doi: 10.1021/tx2001256. Epub 2011 May 3. Chem Res Toxicol. 2011. PMID: 21491947

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