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Structure and autoregulation of the insulin-like growth factor 1 receptor kinase.
Favelyukis S, Till JH, Hubbard SR, Miller WT. Favelyukis S, et al. Nat Struct Biol. 2001 Dec;8(12):1058-63. doi: 10.1038/nsb721. Nat Struct Biol. 2001. PMID: 11694888
Inhibition of insulin-like growth factor I receptor autophosphorylation by novel 6-5 ring-fused compounds.
Li W, Favelyukis S, Yang J, Zeng Y, Yu J, Gangjee A, Miller WT. Li W, et al. Among authors: favelyukis s. Biochem Pharmacol. 2004 Jul 1;68(1):145-54. doi: 10.1016/j.bcp.2004.03.013. Biochem Pharmacol. 2004. PMID: 15183126
MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema.
Gregoire FM, Zhang F, Clarke HJ, Gustafson TA, Sears DD, Favelyukis S, Lenhard J, Rentzeperis D, Clemens LE, Mu Y, Lavan BE. Gregoire FM, et al. Among authors: favelyukis s. Mol Endocrinol. 2009 Jul;23(7):975-88. doi: 10.1210/me.2008-0473. Epub 2009 Apr 23. Mol Endocrinol. 2009. PMID: 19389808 Free PMC article.
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways.
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. Nguyen MT, et al. Among authors: favelyukis s. J Biol Chem. 2007 Nov 30;282(48):35279-92. doi: 10.1074/jbc.M706762200. Epub 2007 Oct 4. J Biol Chem. 2007. PMID: 17916553 Free article.
Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes.
Liao W, Nguyen MT, Yoshizaki T, Favelyukis S, Patsouris D, Imamura T, Verma IM, Olefsky JM. Liao W, et al. Among authors: favelyukis s. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E219-27. doi: 10.1152/ajpendo.00695.2006. Epub 2007 Mar 27. Am J Physiol Endocrinol Metab. 2007. PMID: 17389706 Free article.
JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.
Nguyen MT, Satoh H, Favelyukis S, Babendure JL, Imamura T, Sbodio JI, Zalevsky J, Dahiyat BI, Chi NW, Olefsky JM. Nguyen MT, et al. Among authors: favelyukis s. J Biol Chem. 2005 Oct 21;280(42):35361-71. doi: 10.1074/jbc.M504611200. Epub 2005 Aug 5. J Biol Chem. 2005. PMID: 16085647 Free article.
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