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Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms.
Rashid S, Tavori H, Brown PE, Linton MF, He J, Giunzioni I, Fazio S. Rashid S, et al. Among authors: fazio s. Circulation. 2014 Jul 29;130(5):431-41. doi: 10.1161/CIRCULATIONAHA.113.006720. Epub 2014 May 23. Circulation. 2014. PMID: 25070550 Free PMC article.
Targeting PCSK9 for therapeutic gains.
Shapiro MD, Fazio S, Tavori H. Shapiro MD, et al. Among authors: fazio s. Curr Atheroscler Rep. 2015 Apr;17(4):499. doi: 10.1007/s11883-015-0499-4. Curr Atheroscler Rep. 2015. PMID: 25712137 Free PMC article. Review.
Local effects of human PCSK9 on the atherosclerotic lesion.
Giunzioni I, Tavori H, Covarrubias R, Major AS, Ding L, Zhang Y, DeVay RM, Hong L, Fan D, Predazzi IM, Rashid S, Linton MF, Fazio S. Giunzioni I, et al. Among authors: fazio s. J Pathol. 2016 Jan;238(1):52-62. doi: 10.1002/path.4630. Epub 2015 Nov 13. J Pathol. 2016. PMID: 26333678 Free PMC article.
PCSK9 Association With Lipoprotein(a).
Tavori H, Christian D, Minnier J, Plubell D, Shapiro MD, Yeang C, Giunzioni I, Croyal M, Duell PB, Lambert G, Tsimikas S, Fazio S. Tavori H, et al. Among authors: fazio s. Circ Res. 2016 Jun 24;119(1):29-35. doi: 10.1161/CIRCRESAHA.116.308811. Epub 2016 Apr 27. Circ Res. 2016. PMID: 27121620 Free PMC article.
PCSK9: From Basic Science Discoveries to Clinical Trials.
Shapiro MD, Tavori H, Fazio S. Shapiro MD, et al. Among authors: fazio s. Circ Res. 2018 May 11;122(10):1420-1438. doi: 10.1161/CIRCRESAHA.118.311227. Circ Res. 2018. PMID: 29748367 Free PMC article. Review.
782 results