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HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172.
Feinmesser RL, Gray K, Means AR, Chantry A. Feinmesser RL, et al. Oncogene. 1996 Jun 20;12(12):2725-30. Oncogene. 1996. PMID: 8700533
Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation.
Feinmesser RL, Wicks SJ, Taverner CJ, Chantry A. Feinmesser RL, et al. J Biol Chem. 1999 Jun 4;274(23):16168-73. doi: 10.1074/jbc.274.23.16168. J Biol Chem. 1999. PMID: 10347170 Free article.
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