Felczak K - Search Results

1

Prodrug activation by Cryptosporidium thymidine kinase.

Sun XE, Sharling L, Muthalagi M, Mudeppa DG, Pankiewicz KW, Felczak K, Rathod PK, Mead J, Striepen B, Hedstrom L. Sun XE, et al. Among authors: felczak k. J Biol Chem. 2010 May 21;285(21):15916-22. doi: 10.1074/jbc.M110.101543. Epub 2010 Mar 15. J Biol Chem. 2010. PMID: 20231284 Free PMC article.

2

Multivalent glycocluster design through directed evolution.

MacPherson IS, Temme JS, Habeshian S, Felczak K, Pankiewicz K, Hedstrom L, Krauss IJ. MacPherson IS, et al. Among authors: felczak k. Angew Chem Int Ed Engl. 2011 Nov 18;50(47):11238-42. doi: 10.1002/anie.201105555. Angew Chem Int Ed Engl. 2011. PMID: 22191092 Free PMC article. No abstract available.

3

Rehab of NAD(P)-dependent enzymes with NAD(P)-based inhibitors.

Felczak K, Pankiewicz KW. Felczak K, et al. Curr Med Chem. 2011;18(13):1891-908. doi: 10.2174/092986711795590066. Curr Med Chem. 2011. PMID: 21517781 Review.

4

NAD-based inhibitors with anticancer potential.

Felczak K, Vince R, Pankiewicz KW. Felczak K, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):332-6. doi: 10.1016/j.bmcl.2013.11.005. Epub 2013 Nov 14. Bioorg Med Chem Lett. 2014. PMID: 24269162

5

Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.

Chen L, Gao G, Felczak K, Bonnac L, Patterson SE, Wilson D, Bennett EM, Jayaram HN, Hedstrom L, Pankiewicz KW. Chen L, et al. Among authors: felczak k. J Med Chem. 2007 Nov 15;50(23):5743-51. doi: 10.1021/jm070568j. Epub 2007 Oct 24. J Med Chem. 2007. PMID: 17958343

6

Nicotinamide Adenine Dinucleotide Based Therapeutics, Update.

Pankiewicz KW, Petrelli R, Singh R, Felczak K. Pankiewicz KW, et al. Among authors: felczak k. Curr Med Chem. 2015;22(34):3991-4028. doi: 10.2174/0929867322666150821100720. Curr Med Chem. 2015. PMID: 26295463 Review.

7

Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis.

Chen L, Wilson DJ, Xu Y, Aldrich CC, Felczak K, Sham YY, Pankiewicz KW. Chen L, et al. Among authors: felczak k. J Med Chem. 2010 Jun 24;53(12):4768-78. doi: 10.1021/jm100424m. J Med Chem. 2010. PMID: 20491506 Free PMC article.

8

Synthesis of methylenebis(phosphonate) analogues of 2-, 4-, and 6-pyridones of nicotinamide adenine dinucleotide.

Felczak K, Pankiewicz KW. Felczak K, et al. Nucleosides Nucleotides Nucleic Acids. 2011 Jul-Aug;30(7-8):512-23. doi: 10.1080/15257770.2011.575909. Nucleosides Nucleotides Nucleic Acids. 2011. PMID: 21888543

9

Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.

Felczak K, Chen L, Wilson D, Williams J, Vince R, Petrelli R, Jayaram HN, Kusumanchi P, Kumar M, Pankiewicz KW. Felczak K, et al. Bioorg Med Chem. 2011 Mar 1;19(5):1594-605. doi: 10.1016/j.bmc.2011.01.042. Epub 2011 Jan 27. Bioorg Med Chem. 2011. PMID: 21324702

10

A second target of benzamide riboside: dihydrofolate reductase.

Roussel B, Johnson-Farley N, Kerrigan JE, Scotto KW, Banerjee D, Felczak K, Pankiewicz KW, Gounder M, Lin H, Abali EE, Bertino JR. Roussel B, et al. Among authors: felczak k. Cancer Biol Ther. 2012 Nov;13(13):1290-8. doi: 10.4161/cbt.21786. Epub 2012 Sep 6. Cancer Biol Ther. 2012. PMID: 22954684 Free PMC article.

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