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Translating molecular insights in autoimmunity into effective therapy.
Feldmann M. Feldmann M. Annu Rev Immunol. 2009;27:1-27. doi: 10.1146/annurev-immunol-082708-100732. Annu Rev Immunol. 2009. PMID: 19007330
Anti-TNF therapy: past, present and future.
Monaco C, Nanchahal J, Taylor P, Feldmann M. Monaco C, et al. Int Immunol. 2015 Jan;27(1):55-62. doi: 10.1093/intimm/dxu102. Epub 2014 Nov 19. Int Immunol. 2015. PMID: 25411043 Free PMC article. Review.
Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis.
Taylor PC, Feldmann M. Taylor PC, et al. Nat Rev Rheumatol. 2009 Oct;5(10):578-82. doi: 10.1038/nrrheum.2009.181. Nat Rev Rheumatol. 2009. PMID: 19798034 Review.
Alarmins: awaiting a clinical response.
Chan JK, Roth J, Oppenheim JJ, Tracey KJ, Vogl T, Feldmann M, Horwood N, Nanchahal J. Chan JK, et al. J Clin Invest. 2012 Aug;122(8):2711-9. doi: 10.1172/JCI62423. Epub 2012 Aug 1. J Clin Invest. 2012. PMID: 22850880 Free PMC article. Review.
Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen.
Inglis JJ, Criado G, Medghalchi M, Andrews M, Sandison A, Feldmann M, Williams RO. Inglis JJ, et al. Arthritis Res Ther. 2007;9(5):R113. doi: 10.1186/ar2319. Arthritis Res Ther. 2007. PMID: 17967186 Free PMC article.
Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade.
Gompels LL, Malik NM, Madden L, Jin P, Feldmann M, Shepard HM, Paleolog EM. Gompels LL, et al. Arthritis Res Ther. 2011;13(5):R161. doi: 10.1186/ar3480. Epub 2011 Oct 7. Arthritis Res Ther. 2011. PMID: 21982514 Free PMC article.
Anti-TNF therapy: where have we got to in 2005?
Feldmann M, Brennan FM, Foxwell BM, Taylor PC, Williams RO, Maini RN. Feldmann M, et al. J Autoimmun. 2005;25 Suppl:26-8. doi: 10.1016/j.jaut.2005.09.006. Epub 2005 Nov 2. J Autoimmun. 2005. PMID: 16260118 Review.
Design of effective immunotherapy for human autoimmunity.
Feldmann M, Steinman L. Feldmann M, et al. Nature. 2005 Jun 2;435(7042):612-9. doi: 10.1038/nature03727. Nature. 2005. PMID: 15931214 Review.
Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling.
Sacre SM, Lundberg AM, Andreakos E, Taylor C, Feldmann M, Foxwell BM. Sacre SM, et al. J Immunol. 2007 Feb 15;178(4):2148-54. doi: 10.4049/jimmunol.178.4.2148. J Immunol. 2007. PMID: 17277119
Previously, we showed that MyD88 or Mal dominant-negative constructs did not inhibit LPS induction of cytokines in primary human M-CSF-derived macrophages. ...To investigate a potential role for TRAM in LPS signaling in human M-CSF-derived macrophages, we engineered …
Previously, we showed that MyD88 or Mal dominant-negative constructs did not inhibit LPS induction of cytokines in primary human M-CS …
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