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Telomere dysfunction and the initiation of genome instability.
Feldser DM, Hackett JA, Greider CW. Feldser DM, et al. Nat Rev Cancer. 2003 Aug;3(8):623-7. doi: 10.1038/nrc1142. Nat Rev Cancer. 2003. PMID: 12894250
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.
Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi P, Semenza GL. Krishnamachary B, et al. Cancer Res. 2003 Mar 1;63(5):1138-43. Cancer Res. 2003. PMID: 12615733
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres.
Feldser D, Strong MA, Greider CW. Feldser D, et al. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2249-51. doi: 10.1073/pnas.0511143103. Epub 2006 Feb 7. Proc Natl Acad Sci U S A. 2006. PMID: 16467146 Free PMC article.
Telomere dysfunction increases mutation rate and genomic instability.
Hackett JA, Feldser DM, Greider CW. Hackett JA, et al. Among authors: feldser dm. Cell. 2001 Aug 10;106(3):275-86. doi: 10.1016/s0092-8674(01)00457-3. Cell. 2001. PMID: 11509177
Short telomeres limit tumor progression in vivo by inducing senescence.
Feldser DM, Greider CW. Feldser DM, et al. Cancer Cell. 2007 May;11(5):461-9. doi: 10.1016/j.ccr.2007.02.026. Epub 2007 Apr 12. Cancer Cell. 2007. PMID: 17433785 Free PMC article.
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity.
Hao LY, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW. Hao LY, et al. Among authors: feldser dm. Cell. 2005 Dec 16;123(6):1121-31. doi: 10.1016/j.cell.2005.11.020. Cell. 2005. PMID: 16360040
'The metabolism of tumours': 70 years later.
Semenza GL, Artemov D, Bedi A, Bhujwalla Z, Chiles K, Feldser D, Laughner E, Ravi R, Simons J, Taghavi P, Zhong H. Semenza GL, et al. Novartis Found Symp. 2001;240:251-60; discussion 260-4. Novartis Found Symp. 2001. PMID: 11727934 Review.
Hypoxia, HIF-1, and the pathophysiology of common human diseases.
Semenza GL, Agani F, Feldser D, Iyer N, Kotch L, Laughner E, Yu A. Semenza GL, et al. Adv Exp Med Biol. 2000;475:123-30. doi: 10.1007/0-306-46825-5_12. Adv Exp Med Biol. 2000. PMID: 10849654 Review.
Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.
Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, Semenza GL. Feldser D, et al. Cancer Res. 1999 Aug 15;59(16):3915-8. Cancer Res. 1999. PMID: 10463582
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. Zhong H, et al. Cancer Res. 2000 Mar 15;60(6):1541-5. Cancer Res. 2000. PMID: 10749120
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