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The NAD metabolome--a key determinant of cancer cell biology.
Chiarugi A, Dölle C, Felici R, Ziegler M. Chiarugi A, et al. Nat Rev Cancer. 2012 Nov;12(11):741-52. doi: 10.1038/nrc3340. Epub 2012 Sep 28. Nat Rev Cancer. 2012. PMID: 23018234 Review.
Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes.
Pittelli M, Cavone L, Lapucci A, Oteri C, Felici R, Niccolai E, Amedei A, Chiarugi A. Pittelli M, et al. Immunol Cell Biol. 2014 Feb;92(2):191-9. doi: 10.1038/icb.2013.85. Epub 2013 Nov 26. Immunol Cell Biol. 2014. PMID: 24275857
Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis.
Pittelli M, Felici R, Pitozzi V, Giovannelli L, Bigagli E, Cialdai F, Romano G, Moroni F, Chiarugi A. Pittelli M, et al. Mol Pharmacol. 2011 Dec;80(6):1136-46. doi: 10.1124/mol.111.073916. Epub 2011 Sep 14. Mol Pharmacol. 2011. PMID: 21917911
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia.
Muzzi M, Blasi F, Masi A, Coppi E, Traini C, Felici R, Pittelli M, Cavone L, Pugliese AM, Moroni F, Chiarugi A. Muzzi M, et al. J Cereb Blood Flow Metab. 2013 Feb;33(2):183-90. doi: 10.1038/jcbfm.2012.157. Epub 2012 Oct 24. J Cereb Blood Flow Metab. 2013. PMID: 23093068 Free PMC article.
Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation.
Rapizzi E, Ercolino T, Fucci R, Zampetti B, Felici R, Guasti D, Morandi A, Giannoni E, Giaché V, Bani D, Chiarugi A, Mannelli M. Rapizzi E, et al. Horm Cancer. 2014 Jun;5(3):174-84. doi: 10.1007/s12672-014-0172-3. Epub 2014 Mar 5. Horm Cancer. 2014. PMID: 24595825
PARP inhibition delays progression of mitochondrial encephalopathy in mice.
Felici R, Cavone L, Lapucci A, Guasti D, Bani D, Chiarugi A. Felici R, et al. Neurotherapeutics. 2014 Jul;11(3):651-64. doi: 10.1007/s13311-014-0285-y. Neurotherapeutics. 2014. PMID: 24935635 Free PMC article.
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice.
Lapucci A, Cavone L, Buonvicino D, Felici R, Gerace E, Zwergel C, Valente S, Mai A, Chiarugi A. Lapucci A, et al. Among authors: felici r. Neurosci Lett. 2017 Aug 24;656:120-125. doi: 10.1016/j.neulet.2017.07.033. Epub 2017 Jul 19. Neurosci Lett. 2017. PMID: 28732762
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