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Crystal structure of dihydroorotate dehydrogenase from Leishmania major.
Cordeiro AT, Feliciano PR, Pinheiro MP, Nonato MC. Cordeiro AT, et al. Among authors: feliciano pr. Biochimie. 2012 Aug;94(8):1739-48. doi: 10.1016/j.biochi.2012.04.003. Epub 2012 Apr 21. Biochimie. 2012. PMID: 22542640 Free article.
Fumarate hydratase isoforms of Leishmania major: subcellular localization, structural and kinetic properties.
Feliciano PR, Gupta S, Dyszy F, Dias-Baruffi M, Costa-Filho AJ, Michels PA, Nonato MC. Feliciano PR, et al. Int J Biol Macromol. 2012 Jul-Aug;51(1-2):25-31. doi: 10.1016/j.ijbiomac.2012.04.025. Epub 2012 May 5. Int J Biol Macromol. 2012. PMID: 22569531 Free article.
Crystallization and preliminary X-ray diffraction analysis of Leishmania major dihydroorotate dehydrogenase.
Cordeiro AT, Feliciano PR, Nonato MC. Cordeiro AT, et al. Among authors: feliciano pr. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt 10):1049-51. doi: 10.1107/S1744309106038966. Epub 2006 Sep 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17012810 Free PMC article.
Cloning, expression, purification, and characterization of Leishmania major dihydroorotate dehydrogenase.
Feliciano PR, Cordeiro AT, Costa-Filho AJ, Nonato MC. Feliciano PR, et al. Protein Expr Purif. 2006 Jul;48(1):98-103. doi: 10.1016/j.pep.2006.02.010. Epub 2006 Mar 10. Protein Expr Purif. 2006. PMID: 16600626
Crystal structure of an Fe-S cluster-containing fumarate hydratase enzyme from Leishmania major reveals a unique protein fold.
Feliciano PR, Drennan CL, Nonato MC. Feliciano PR, et al. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9804-9. doi: 10.1073/pnas.1605031113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528683 Free PMC article.
Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
Feliciano PR, Drennan CL, Nonato MC. Feliciano PR, et al. ACS Chem Biol. 2019 Feb 15;14(2):266-275. doi: 10.1021/acschembio.8b00972. Epub 2019 Jan 24. ACS Chem Biol. 2019. PMID: 30645090 Free PMC article.
Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.
Azeredo LFSP, Coutinho JP, Jabor VAP, Feliciano PR, Nonato MC, Kaiser CR, Menezes CMS, Hammes ASO, Caffarena ER, Hoelz LVB, de Souza NB, Pereira GAN, Cerávolo IP, Krettli AU, Boechat N. Azeredo LFSP, et al. Among authors: feliciano pr. Eur J Med Chem. 2017 Jan 27;126:72-83. doi: 10.1016/j.ejmech.2016.09.073. Epub 2016 Sep 30. Eur J Med Chem. 2017. PMID: 27744189
Crystal structure and molecular dynamics studies of L-amino acid oxidase from Bothrops atrox.
Feliciano PR, Rustiguel JK, Soares RO, Sampaio SV, Cristina Nonato M. Feliciano PR, et al. Toxicon. 2017 Mar 15;128:50-59. doi: 10.1016/j.toxicon.2017.01.017. Epub 2017 Jan 27. Toxicon. 2017. PMID: 28137621
A rational protocol for the successful crystallization of L-amino-acid oxidase from Bothrops atrox.
Alves RM, Feliciano PR, Sampaio SV, Nonato MC. Alves RM, et al. Among authors: feliciano pr. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Apr 1;67(Pt 4):475-8. doi: 10.1107/S1744309111003770. Epub 2011 Mar 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21505245 Free PMC article.
The dihydroorotate dehydrogenases: Past and present.
Reis RAG, Calil FA, Feliciano PR, Pinheiro MP, Nonato MC. Reis RAG, et al. Among authors: feliciano pr. Arch Biochem Biophys. 2017 Oct 15;632:175-191. doi: 10.1016/j.abb.2017.06.019. Epub 2017 Jun 27. Arch Biochem Biophys. 2017. PMID: 28666740 Review.
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