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Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells.
Versantvoort CH, Broxterman HJ, Lankelma J, Feller N, Pinedo HM. Versantvoort CH, et al. Biochem Pharmacol. 1994 Sep 15;48(6):1129-36. doi: 10.1016/0006-2952(94)90149-x. Biochem Pharmacol. 1994. PMID: 7945406
Function of the ABC transporters, P-glycoprotein, multidrug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia.
van der Pol MA, Broxterman HJ, Pater JM, Feller N, van der Maas M, Weijers GW, Scheffer GL, Allen JD, Scheper RJ, van Loevezijn A, Ossenkoppele GJ, Schuurhuis GJ. van der Pol MA, et al. Haematologica. 2003 Feb;88(2):134-47. Haematologica. 2003. PMID: 12604403
Overall, no consistent changes were observed at follow-up [during chemotherapy (n=20), MRD (n=37), relapse (n=26))] in forty-five patients, the mean activities (as percentages of values at diagnosis) were 97% (Pgp), 103% (MRP) and 102% (BCRP). ...
Overall, no consistent changes were observed at follow-up [during chemotherapy (n=20), MRD (n=37), relapse (n=26))] in …
Functional characterization of minimal residual disease for P-glycoprotein and multidrug resistance protein activity in acute myeloid leukemia.
van der Pol MA, Pater JM, Feller N, Westra AH, van Stijn A, Ossenkoppele GJ, Broxterman HJ, Schuurhuis GJ. van der Pol MA, et al. Leukemia. 2001 Oct;15(10):1554-63. doi: 10.1038/sj.leu.2402245. Leukemia. 2001. PMID: 11587213
In addition, no significant differences were found when comparing fresh and cryopreserved de novo AML for LAP expression (n = 43), Pgp (n = 30) and MRP (n = 24) function and for MRD samples for simultaneous LAP expression and Pgp/MRP activity (n = 10). …
In addition, no significant differences were found when comparing fresh and cryopreserved de novo AML for LAP expression (n = 43), Pg …
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts.
Jansen WJ, Pinedo HM, van der Wilt CL, Feller N, Bamberger U, Boven E. Jansen WJ, et al. Eur J Cancer. 1995 Dec;31A(13-14):2313-9. doi: 10.1016/0959-8049(95)00440-8. Eur J Cancer. 1995. PMID: 8652262
Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity.
Broxterman HJ, Sonneveld P, Feller N, Ossenkoppele GJ, Währer DC, Eekman CA, Schoester M, Lankelma J, Pinedo HM, Löwenberg B, Schuurhuis GJ. Broxterman HJ, et al. Blood. 1996 Jun 1;87(11):4809-16. Blood. 1996. PMID: 8639853
The correlation between the DNR/PSC833 and R123/PSC833 test was r = .86 (N = 51). The modulation of drug accumulation by 8 micromol/L verapamil was the some as the PSC833 effect for DNR (117%, N = 21), but was higher for vincristine in every single case (161% v 121% …
The correlation between the DNR/PSC833 and R123/PSC833 test was r = .86 (N = 51). The modulation of drug accumulation by 8 micromol/L …
Cortisol is transported by the multidrug resistance gene product P-glycoprotein.
van Kalken CK, Broxterman HJ, Pinedo HM, Feller N, Dekker H, Lankelma J, Giaccone G. van Kalken CK, et al. Br J Cancer. 1993 Feb;67(2):284-9. doi: 10.1038/bjc.1993.54. Br J Cancer. 1993. PMID: 8094292 Free PMC article.
Correlation between functional and molecular analysis of mdr1 P-glycoprotein in human solid-tumor xenografts.
Broxterman HJ, Feller N, Kuiper CM, Boven E, Versantvoort CH, Teerlink T, Pinedo HM, Lankelma J. Broxterman HJ, et al. Int J Cancer. 1995 Jun 9;61(6):880-6. doi: 10.1002/ijc.2910610622. Int J Cancer. 1995. PMID: 7790125
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