Feng JY - Search Results

1

Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication.

Murakami E, Feng JY, Lee H, Hanes J, Johnson KA, Anderson KS. Murakami E, et al. Among authors: feng jy. J Biol Chem. 2003 Sep 19;278(38):36403-9. doi: 10.1074/jbc.M306236200. Epub 2003 Jul 10. J Biol Chem. 2003. PMID: 12857740 Free article.

2

Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma.

Ray AS, Feng JY, Murakami E, Chu CK, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: feng jy. Antivir Chem Chemother. 2007;18(1):25-33. doi: 10.1177/095632020701800103. Antivir Chem Chemother. 2007. PMID: 17354649 Free article.

3

Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase.

Feng JY, Anderson KS. Feng JY, et al. Biochemistry. 1999 Jan 5;38(1):55-63. doi: 10.1021/bi982340r. Biochemistry. 1999. PMID: 9890882

4

Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase.

Feng JY, Anderson KS. Feng JY, et al. Biochemistry. 1999 Jul 20;38(29):9440-8. doi: 10.1021/bi990709m. Biochemistry. 1999. PMID: 10413520

5

Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs.

Feng JY, Johnson AA, Johnson KA, Anderson KS. Feng JY, et al. J Biol Chem. 2001 Jun 29;276(26):23832-7. doi: 10.1074/jbc.M101156200. Epub 2001 Apr 27. J Biol Chem. 2001. PMID: 11328813 Free article.

6

Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.

Jeffrey JL, Feng JY, Qi CC, Anderson KS, Furman PA. Jeffrey JL, et al. Among authors: feng jy. J Biol Chem. 2003 May 23;278(21):18971-9. doi: 10.1074/jbc.M210113200. Epub 2003 Mar 21. J Biol Chem. 2003. PMID: 12651859 Free article.

7

Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase.

Feng JY, Murakami E, Zorca SM, Johnson AA, Johnson KA, Schinazi RF, Furman PA, Anderson KS. Feng JY, et al. Antimicrob Agents Chemother. 2004 Apr;48(4):1300-6. doi: 10.1128/AAC.48.4.1300-1306.2004. Antimicrob Agents Chemother. 2004. PMID: 15047533 Free PMC article.

8

Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP.

Feng JY, Shi J, Schinazi RF, Anderson KS. Feng JY, et al. FASEB J. 1999 Sep;13(12):1511-7. doi: 10.1096/fasebj.13.12.1511. FASEB J. 1999. PMID: 10463941

9

Bifunctional inhibition of HIV-1 reverse transcriptase: a first step in designing a bifunctional triphosphate.

Piao D, Basavapathruni A, Iyidogan P, Dai G, Hinz W, Ray AS, Murakami E, Feng JY, You F, Dutschman GE, Austin DJ, Parker KA, Anderson KS. Piao D, et al. Among authors: feng jy. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1511-8. doi: 10.1016/j.bmcl.2012.12.015. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23380374 Free PMC article.

10

Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase.

Appleby TC, Perry JK, Murakami E, Barauskas O, Feng J, Cho A, Fox D 3rd, Wetmore DR, McGrath ME, Ray AS, Sofia MJ, Swaminathan S, Edwards TE. Appleby TC, et al. Science. 2015 Feb 13;347(6223):771-5. doi: 10.1126/science.1259210. Science. 2015. PMID: 25678663

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