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Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora.
Kim MC, Machado H, Jang KH, Trzoss L, Jensen PR, Fenical W. Kim MC, et al. J Am Chem Soc. 2018 Aug 29;140(34):10775-10784. doi: 10.1021/jacs.8b04848. Epub 2018 Aug 20. J Am Chem Soc. 2018. PMID: 30085661 Free PMC article.
Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality.
Amos GCA, Awakawa T, Tuttle RN, Letzel AC, Kim MC, Kudo Y, Fenical W, Moore BS, Jensen PR. Amos GCA, et al. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11121-E11130. doi: 10.1073/pnas.1714381115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229817 Free PMC article.
Two of a Kind--The Biosynthetic Pathways of Chlorotonil and Anthracimycin.
Jungmann K, Jansen R, Gerth K, Huch V, Krug D, Fenical W, Müller R. Jungmann K, et al. ACS Chem Biol. 2015 Nov 20;10(11):2480-90. doi: 10.1021/acschembio.5b00523. Epub 2015 Sep 8. ACS Chem Biol. 2015. PMID: 26348978
Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp.
Hassan HM, Degen D, Jang KH, Ebright RH, Fenical W. Hassan HM, et al. J Antibiot (Tokyo). 2015 Mar;68(3):206-9. doi: 10.1038/ja.2014.122. Epub 2014 Sep 17. J Antibiot (Tokyo). 2015. PMID: 25227504 Free PMC article. No abstract available.
Challenges and triumphs to genomics-based natural product discovery.
Jensen PR, Chavarria KL, Fenical W, Moore BS, Ziemert N. Jensen PR, et al. J Ind Microbiol Biotechnol. 2014 Feb;41(2):203-9. doi: 10.1007/s10295-013-1353-8. Epub 2013 Oct 9. J Ind Microbiol Biotechnol. 2014. PMID: 24104399 Free PMC article.
Nocarimidazoles A and B from a Marine-Derived Actinomycete of the Genus Nocardiopsis.
Leutou AS, Yang I, Kang H, Seo EK, Nam SJ, Fenical W. Leutou AS, et al. J Nat Prod. 2015 Nov 25;78(11):2846-9. doi: 10.1021/acs.jnatprod.5b00746. Epub 2015 Oct 16. J Nat Prod. 2015. PMID: 26474119
Previously Uncultured Marine Bacteria Linked to Novel Alkaloid Production.
Choi EJ, Nam SJ, Paul L, Beatty D, Kauffman CA, Jensen PR, Fenical W. Choi EJ, et al. Chem Biol. 2015 Sep 17;22(9):1270-9. doi: 10.1016/j.chembiol.2015.07.014. Epub 2015 Aug 20. Chem Biol. 2015. PMID: 26299672
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