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Coordinate activation of human platelet protease-activated receptor-1 and -4 in response to subnanomolar alpha-thrombin.
Ofosu FA, Dewar L, Craven SJ, Song Y, Cedrone A, Freedman J, Fenton JW 2nd. Ofosu FA, et al. Among authors: fenton jw 2nd. J Biol Chem. 2008 Oct 3;283(40):26886-93. doi: 10.1074/jbc.M802237200. Epub 2008 Aug 5. J Biol Chem. 2008. PMID: 18682394 Free article.
Impact of simvastatin on hemostatic and fibrinolytic regulators in Type 2 diabetes mellitus.
Ludwig S, Dharmalingam S, Erickson-Nesmith S, Ren S, Zhu F, Ma GM, Zhao R, Fenton JW 2nd, Ofosu FA, Velthuis HT, van Mierlo G, Shen GX. Ludwig S, et al. Among authors: fenton jw 2nd. Diabetes Res Clin Pract. 2005 Nov;70(2):110-8. doi: 10.1016/j.diabres.2005.03.025. Diabetes Res Clin Pract. 2005. PMID: 16188573 Clinical Trial.
Statins and thrombin.
Fenton JW 2nd, Brezniak DV, Ofosu FA, Shen GX, Jacobson JR, Garcia JG. Fenton JW 2nd, et al. Curr Drug Targets Cardiovasc Haematol Disord. 2005 Apr;5(2):115-20. doi: 10.2174/1568006043586189. Curr Drug Targets Cardiovasc Haematol Disord. 2005. PMID: 15853752 Review.
Statin drugs and dietary isoprenoids downregulate protein prenylation in signal transduction and are antithrombotic and prothrombolytic agents.
Fenton JW 2nd, Jeske WP, Catalfamo JL, Brezniak DV, Moon DG, Shen GX. Fenton JW 2nd, et al. Biochemistry (Mosc). 2002 Jan;67(1):85-91. doi: 10.1023/a:1013956215394. Biochemistry (Mosc). 2002. PMID: 11841343 Free article. Review.
Depletion of protein kinase Cepsilon in normal and scleroderma lung fibroblasts has opposite effects on tenascin expression.
Tourkina E, Hoffman S, Fenton JW 2nd, Lipsitz S, Silver RM, Ludwicka-Bradley A. Tourkina E, et al. Among authors: fenton jw 2nd. Arthritis Rheum. 2001 Jun;44(6):1370-81. doi: 10.1002/1529-0131(200106)44:6<1370::AID-ART230>3.0.CO;2-2. Arthritis Rheum. 2001. PMID: 11407697 Free article.
Statin drugs and dietary isoprenoids as antithrombotic agents.
Fenton JW 2nd, Shen GX, Minnear FL, Brezniak DV, Jeske WP, Walenga JM, Bognacki JJ, Ofosu FA, Hassouna HI. Fenton JW 2nd, et al. Hematol Oncol Clin North Am. 2000 Apr;14(2):483-90, xi. doi: 10.1016/s0889-8588(05)70147-7. Hematol Oncol Clin North Am. 2000. PMID: 10806569 Review.
Hirulog-1 reduces expression of platelet-derived growth factor in neointima of rat carotid artery induced by balloon catheter injury.
Xue M, Fenton JW 2nd, Shen GX. Xue M, et al. Among authors: fenton jw 2nd. J Vasc Res. 2000 Mar-Apr;37(2):82-92. doi: 10.1159/000025719. J Vasc Res. 2000. PMID: 10754393
Statins induce hypothrombotic states?
Fenton JW 2nd, Shen GX, Minnear FL, Brezniak DV, Walenga JM, Bognacki JJ, Ofosu FA. Fenton JW 2nd, et al. Clin Appl Thromb Hemost. 2000 Jan;6(1):18-21. doi: 10.1177/107602960000600103. Clin Appl Thromb Hemost. 2000. PMID: 10726044 Free article. Review. No abstract available.
Thrombin upregulates interleukin-8 in lung fibroblasts via cleavage of proteolytically activated receptor-I and protein kinase C-gamma activation.
Ludwicka-Bradley A, Tourkina E, Suzuki S, Tyson E, Bonner M, Fenton JW 2nd, Hoffman S, Silver RM. Ludwicka-Bradley A, et al. Among authors: fenton jw 2nd. Am J Respir Cell Mol Biol. 2000 Feb;22(2):235-43. doi: 10.1165/ajrcmb.22.2.3642. Am J Respir Cell Mol Biol. 2000. PMID: 10657945
Role of thrombin receptor in breast cancer invasiveness.
Henrikson KP, Salazar SL, Fenton JW 2nd, Pentecost BT. Henrikson KP, et al. Among authors: fenton jw 2nd. Br J Cancer. 1999 Feb;79(3-4):401-6. doi: 10.1038/sj.bjc.6690063. Br J Cancer. 1999. PMID: 10027305 Free PMC article.
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