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Influenza vaccine based on AS03-adjuvanted chimeric HA induces long-lived stalk-specific plasma cells in bone marrow and lymph nodes of nonhuman primates.
Akhtar A, Styles TM, Gu C, León AN, Tharp GK, Stokdyk K, Abbad A, Hirst C, Strohmeier S, Neumann G, Richey ST, Ferguson JA, Mala U, Ahmed H, Han J, Carreño JM, Davis CW, Antia R, Palese P, Ward AB, Kawaoka Y, Krammer F, Ahmed R, Amara RR. Akhtar A, et al. Among authors: ferguson ja. Nat Immunol. 2025 Nov;26(11):2045-2058. doi: 10.1038/s41590-025-02309-1. Epub 2025 Oct 15. Nat Immunol. 2025. PMID: 41094203 Free PMC article.
Flipping hemagglutinin on its head.
Ferguson JA, Han J, Ward AB. Ferguson JA, et al. Nat Chem Biol. 2024 Aug;20(8):944-945. doi: 10.1038/s41589-024-01545-0. Nat Chem Biol. 2024. PMID: 38321208 No abstract available.
Broadly inhibitory antibodies to severe malaria virulence proteins.
Reyes RA, Raghavan SSR, Hurlburt NK, Introini V, Bol S, Kana IH, Jensen RW, Martinez-Scholze E, Gestal-Mato M, López-Gutiérrez B, Sanz S, Bancells C, Fernández-Quintero ML, Loeffler JR, Ferguson JA, Lee WH, Martin GM, Theander TG, Lusingu JPA, Minja DTR, Ssewanyana I, Feeney ME, Greenhouse B, Ward AB, Bernabeu M, Pancera M, Turner L, Bunnik EM, Lavstsen T. Reyes RA, et al. Among authors: ferguson ja. Nature. 2024 Dec;636(8041):182-189. doi: 10.1038/s41586-024-08220-3. Epub 2024 Nov 20. Nature. 2024. PMID: 39567685 Free PMC article.
Isolation of genetically diverse influenza antibodies highlights the role of IG germline gene variation and informs the design of population-comprehensive vaccine strategies.
Fischer AA, Corcoran M, Brouwer PJM, Chernyshev M, Gillespie RA, Nicoletto A, Loeffler JR, Ferguson JA, Rodriguez AJ, Narang S, van Gils MJ, Castro Dopico X, Kanekiyo M, Ward AB, Han J, Karlsson Hedestam GB. Fischer AA, et al. Among authors: ferguson ja. bioRxiv [Preprint]. 2025 Jul 7:2025.07.04.663145. doi: 10.1101/2025.07.04.663145. bioRxiv. 2025. PMID: 40747420 Free PMC article. Preprint.
Structural basis of broad protection against influenza virus by human antibodies targeting the neuraminidase active site via a recurring motif in CDR H3.
Jo G, Yamayoshi S, Ma KM, Swanson O, Torres JL, Ferguson JA, Fernández-Quintero ML, Huang J, Copps J, Rodriguez AJ, Steichen JM, Kawaoka Y, Han J, Ward AB. Jo G, et al. Among authors: ferguson ja. Nat Commun. 2025 Aug 1;16(1):7067. doi: 10.1038/s41467-025-62174-2. Nat Commun. 2025. PMID: 40750588 Free PMC article.
185 results