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Beyond indigestion: emerging roles for lysosome-based signaling in human disease.
Ferguson SM. Ferguson SM. Curr Opin Cell Biol. 2015 Aug;35:59-68. doi: 10.1016/ Epub 2015 May 15. Curr Opin Cell Biol. 2015. PMID: 25950843 Free PMC article. Review.
Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits.
Ferguson SM, Raimondi A, Paradise S, Shen H, Mesaki K, Ferguson A, Destaing O, Ko G, Takasaki J, Cremona O, O' Toole E, De Camilli P. Ferguson SM, et al. Dev Cell. 2009 Dec;17(6):811-22. doi: 10.1016/j.devcel.2009.11.005. Dev Cell. 2009. PMID: 20059951 Free PMC article.
Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin.
Shen H, Ferguson SM, Dephoure N, Park R, Yang Y, Volpicelli-Daley L, Gygi S, Schlessinger J, De Camilli P. Shen H, et al. Mol Biol Cell. 2011 Feb 15;22(4):493-502. doi: 10.1091/mbc.E10-07-0637. Epub 2010 Dec 17. Mol Biol Cell. 2011. PMID: 21169560 Free PMC article.
Dynamin, a membrane-remodelling GTPase.
Ferguson SM, De Camilli P. Ferguson SM, et al. Nat Rev Mol Cell Biol. 2012 Jan 11;13(2):75-88. doi: 10.1038/nrm3266. Nat Rev Mol Cell Biol. 2012. PMID: 22233676 Free PMC article. Review.
Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane.
Sousa LP, Lax I, Shen H, Ferguson SM, De Camilli P, Schlessinger J. Sousa LP, et al. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4419-24. doi: 10.1073/pnas.1200164109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371560 Free PMC article.
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.
Roczniak-Ferguson A, Petit CS, Froehlich F, Qian S, Ky J, Angarola B, Walther TC, Ferguson SM. Roczniak-Ferguson A, et al. Sci Signal. 2012 Jun 12;5(228):ra42. doi: 10.1126/scisignal.2002790. Sci Signal. 2012. PMID: 22692423 Free PMC article.
Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors.
Park RJ, Shen H, Liu L, Liu X, Ferguson SM, De Camilli P. Park RJ, et al. J Cell Sci. 2013 Nov 15;126(Pt 22):5305-12. doi: 10.1242/jcs.138578. Epub 2013 Sep 17. J Cell Sci. 2013. PMID: 24046449 Free PMC article.
Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis.
Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC. Lee MY, et al. Development. 2014 Apr;141(7):1465-72. doi: 10.1242/dev.104539. Epub 2014 Mar 5. Development. 2014. PMID: 24598168 Free PMC article.
Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling.
Willinger T, Ferguson SM, Pereira JP, De Camilli P, Flavell RA. Willinger T, et al. J Exp Med. 2014 Apr 7;211(4):685-700. doi: 10.1084/jem.20131343. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638168 Free PMC article.
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