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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.
Nemoto S, Fergusson MM, Finkel T. Nemoto S, et al. Among authors: fergusson mm. J Biol Chem. 2005 Apr 22;280(16):16456-60. doi: 10.1074/jbc.M501485200. Epub 2005 Feb 16. J Biol Chem. 2005. PMID: 15716268
Regulation of cellular oncosis by uncoupling protein 2.
Mills EM, Xu D, Fergusson MM, Combs CA, Xu Y, Finkel T. Mills EM, et al. Among authors: fergusson mm. J Biol Chem. 2002 Jul 26;277(30):27385-92. doi: 10.1074/jbc.M111860200. Epub 2002 May 14. J Biol Chem. 2002. PMID: 12011039
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.
Nemoto S, Fergusson MM, Finkel T. Nemoto S, et al. Among authors: fergusson mm. Science. 2004 Dec 17;306(5704):2105-8. doi: 10.1126/science.1101731. Science. 2004. PMID: 15604409
The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism.
Nemoto S, Combs CA, French S, Ahn BH, Fergusson MM, Balaban RS, Finkel T. Nemoto S, et al. Among authors: fergusson mm. J Biol Chem. 2006 Apr 14;281(15):10555-60. doi: 10.1074/jbc.M511626200. Epub 2006 Feb 14. J Biol Chem. 2006. PMID: 16481327
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T. Narayan N, et al. Among authors: fergusson mm. Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Nature. 2012. PMID: 23201684 Retracted.
Wnt signaling regulates hepatic metabolism.
Liu H, Fergusson MM, Wu JJ, Rovira II, Liu J, Gavrilova O, Lu T, Bao J, Han D, Sack MN, Finkel T. Liu H, et al. Among authors: fergusson mm. Sci Signal. 2011 Feb 1;4(158):ra6. doi: 10.1126/scisignal.2001249. Sci Signal. 2011. PMID: 21285411 Free PMC article.
Augmented Wnt signaling in a mammalian model of accelerated aging.
Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, Malide D, Rovira II, Schimel D, Kuo CJ, Gutkind JS, Hwang PM, Finkel T. Liu H, et al. Among authors: fergusson mm. Science. 2007 Aug 10;317(5839):803-6. doi: 10.1126/science.1143578. Science. 2007. PMID: 17690294
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
Pan X, Liu J, Nguyen T, Liu C, Sun J, Teng Y, Fergusson MM, Rovira II, Allen M, Springer DA, Aponte AM, Gucek M, Balaban RS, Murphy E, Finkel T. Pan X, et al. Among authors: fergusson mm. Nat Cell Biol. 2013 Dec;15(12):1464-72. doi: 10.1038/ncb2868. Epub 2013 Nov 10. Nat Cell Biol. 2013. PMID: 24212091 Free PMC article.
Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.
Quijano C, Cao L, Fergusson MM, Romero H, Liu J, Gutkind S, Rovira II, Mohney RP, Karoly ED, Finkel T. Quijano C, et al. Among authors: fergusson mm. Cell Cycle. 2012 Apr 1;11(7):1383-92. doi: 10.4161/cc.19800. Epub 2012 Apr 1. Cell Cycle. 2012. PMID: 22421146 Free PMC article.
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy.
Wu JJ, Quijano C, Chen E, Liu H, Cao L, Fergusson MM, Rovira II, Gutkind S, Daniels MP, Komatsu M, Finkel T. Wu JJ, et al. Among authors: fergusson mm. Aging (Albany NY). 2009 Apr 9;1(4):425-37. doi: 10.18632/aging.100038. Aging (Albany NY). 2009. PMID: 20157526 Free PMC article.
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