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Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.
Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM. Fernández-Del-Río L, et al. Free Radic Biol Med. 2017 Sep;110:176-187. doi: 10.1016/j.freeradbiomed.2017.06.006. Epub 2017 Jun 9. Free Radic Biol Med. 2017. PMID: 28603085 Free PMC article.
Mitochondrial ultrastructure and markers of dynamics in hepatocytes from aged, calorie restricted mice fed with different dietary fats.
Khraiwesh H, López-Domínguez JA, Fernández del Río L, Gutierrez-Casado E, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, Burón MI, Villalba JM, González-Reyes JA. Khraiwesh H, et al. Exp Gerontol. 2014 Aug;56:77-88. doi: 10.1016/j.exger.2014.03.023. Epub 2014 Apr 4. Exp Gerontol. 2014. PMID: 24704714 Free PMC article.
Olive Oil and the Hallmarks of Aging.
Fernández del Río L, Gutiérrez-Casado E, Varela-López A, Villalba JM. Fernández del Río L, et al. Molecules. 2016 Jan 29;21(2):163. doi: 10.3390/molecules21020163. Molecules. 2016. PMID: 26840281 Free PMC article. Review.
Ubiquinol Effects on Antiphospholipid Syndrome Prothrombotic Profile: A Randomized, Placebo-Controlled Trial.
Pérez-Sánchez C, Aguirre MÁ, Ruiz-Limón P, Ábalos-Aguilera MC, Jiménez-Gómez Y, Arias-de la Rosa I, Rodriguez-Ariza A, Fernández-Del Río L, González-Reyes JA, Segui P, Collantes-Estévez E, Barbarroja N, Velasco F, Sciascia S, Cecchi I, Cuadrado MJ, Villalba JM, López-Pedrera C. Pérez-Sánchez C, et al. Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1923-1932. doi: 10.1161/ATVBAHA.117.309225. Epub 2017 Jul 6. Arterioscler Thromb Vasc Biol. 2017. PMID: 28684614 Free article. Clinical Trial.
Coenzyme Q10 deficiencies: pathways in yeast and humans.
Awad AM, Bradley MC, Fernández-Del-Río L, Nag A, Tsui HS, Clarke CF. Awad AM, et al. Essays Biochem. 2018 Jul 20;62(3):361-376. doi: 10.1042/EBC20170106. Print 2018 Jul 20. Essays Biochem. 2018. PMID: 29980630 Free PMC article. Review.
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment.
Widmeier E, Yu S, Nag A, Chung YW, Nakayama M, Fernández-Del-Río L, Hugo H, Schapiro D, Buerger F, Choi WI, Helmstädter M, Kim JW, Ryu JH, Lee MG, Clarke CF, Hildebrandt F, Gee HY. Widmeier E, et al. Among authors: fernandez del rio l. J Am Soc Nephrol. 2020 Jun;31(6):1191-1211. doi: 10.1681/ASN.2019070756. Epub 2020 May 7. J Am Soc Nephrol. 2020. PMID: 32381600 Free PMC article.
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