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99 results
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The ATR barrier to replication-born DNA damage.
López-Contreras AJ, Fernandez-Capetillo O. López-Contreras AJ, et al. DNA Repair (Amst). 2010 Dec 10;9(12):1249-55. doi: 10.1016/j.dnarep.2010.09.012. Epub 2010 Oct 30. DNA Repair (Amst). 2010. PMID: 21036674 Free PMC article. Review.
Late-replicating CNVs as a source of new genes.
Juan D, Rico D, Marques-Bonet T, Fernández-Capetillo O, Valencia A. Juan D, et al. Biol Open. 2013 Dec 15;2(12):1402-11. doi: 10.1242/bio.20136924. Biol Open. 2013. PMID: 24285712 Free PMC article.
Global chromatin compaction limits the strength of the DNA damage response.
Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, Cuadrado M, Yang SM, Blasco MA, Skoultchi AI, Fernandez-Capetillo O. Murga M, et al. J Cell Biol. 2007 Sep 24;178(7):1101-8. doi: 10.1083/jcb.200704140. J Cell Biol. 2007. PMID: 17893239 Free PMC article.
INK4a/ARF limits the expansion of cells suffering from replication stress.
Monasor A, Murga M, Lopez-Contreras AJ, Navas C, Gomez G, Pisano DG, Fernandez-Capetillo O. Monasor A, et al. Cell Cycle. 2013 Jun 15;12(12):1948-54. doi: 10.4161/cc.25017. Epub 2013 May 15. Cell Cycle. 2013. PMID: 23676215 Free PMC article.
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.
Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, Nussenzweig A. Difilippantonio S, et al. Nat Cell Biol. 2005 Jul;7(7):675-85. doi: 10.1038/ncb1270. Epub 2005 Jun 19. Nat Cell Biol. 2005. PMID: 15965469
H2AX: the histone guardian of the genome.
Fernandez-Capetillo O, Lee A, Nussenzweig M, Nussenzweig A. Fernandez-Capetillo O, et al. DNA Repair (Amst). 2004 Aug-Sep;3(8-9):959-67. doi: 10.1016/j.dnarep.2004.03.024. DNA Repair (Amst). 2004. PMID: 15279782 Review.
Phosphorylation of histone H2B at DNA double-strand breaks.
Fernandez-Capetillo O, Allis CD, Nussenzweig A. Fernandez-Capetillo O, et al. J Exp Med. 2004 Jun 21;199(12):1671-7. doi: 10.1084/jem.20032247. Epub 2004 Jun 14. J Exp Med. 2004. PMID: 15197225 Free PMC article.
Focusing on foci: H2AX and the recruitment of DNA-damage response factors.
Fernandez-Capetillo O, Celeste A, Nussenzweig A. Fernandez-Capetillo O, et al. Cell Cycle. 2003 Sep-Oct;2(5):426-7. Cell Cycle. 2003. PMID: 12963833 Review. No abstract available.
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. Fernandez-Capetillo O, et al. Nat Cell Biol. 2002 Dec;4(12):993-7. doi: 10.1038/ncb884. Nat Cell Biol. 2002. PMID: 12447390
CGK733 does not inhibit ATM or ATR kinase activity in H460 human lung cancer cells.
Choi S, Toledo LI, Fernandez-Capetillo O, Bakkenist CJ. Choi S, et al. DNA Repair (Amst). 2011 Oct 10;10(10):1000-1; author reply 1002. doi: 10.1016/j.dnarep.2011.07.013. Epub 2011 Aug 23. DNA Repair (Amst). 2011. PMID: 21865098 Free PMC article. No abstract available.
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