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Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia.
Ferrand-Drake M, Zhu C, Gidö G, Hansen AJ, Karlsson JO, Bahr BA, Zamzami N, Kroemer G, Chan PH, Wieloch T, Blomgren K. Ferrand-Drake M, et al. J Neurochem. 2003 Jun;85(6):1431-42. doi: 10.1046/j.1471-4159.2003.01794.x. J Neurochem. 2003. PMID: 12787063 Free article.
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