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A novel I221L substitution in neuraminidase confers high-level resistance to oseltamivir in influenza B viruses.
Escuret V, Collins PJ, Casalegno JS, Vachieri SG, Cattle N, Ferraris O, Sabatier M, Frobert E, Caro V, Skehel JJ, Gamblin S, Valla F, Valette M, Ottmann M, McCauley JW, Daniels RS, Lina B. Escuret V, et al. Among authors: ferraris o. J Infect Dis. 2014 Oct 15;210(8):1260-9. doi: 10.1093/infdis/jiu244. Epub 2014 May 3. J Infect Dis. 2014. PMID: 24795482 Free PMC article.
Measurement of enzymatic activity and specificity of human and avian influenza neuraminidases from whole virus by glycoarray and MALDI-TOF mass spectrometry.
Pourceau G, Chevolot Y, Goudot A, Giroux F, Meyer A, Moulés V, Lina B, Cecioni S, Vidal S, Yu H, Chen X, Ferraris O, Praly JP, Souteyrand E, Vasseur JJ, Morvan F. Pourceau G, et al. Among authors: ferraris o. Chembiochem. 2011 Sep 5;12(13):2071-80. doi: 10.1002/cbic.201100128. Epub 2011 Jul 7. Chembiochem. 2011. PMID: 21739555
H1N1 influenza A virus neuraminidase modulates infectivity in mice.
Ferraris O, Escuret V, Bouscambert M, Casalegno JS, Jacquot F, Raoul H, Caro V, Valette M, Lina B, Ottmann M. Ferraris O, et al. Antiviral Res. 2012 Mar;93(3):374-80. doi: 10.1016/j.antiviral.2012.01.008. Epub 2012 Feb 1. Antiviral Res. 2012. PMID: 22321413
Rescue of a H3N2 influenza virus containing a deficient neuraminidase protein by a hemagglutinin with a low receptor-binding affinity.
Richard M, Erny A, Caré B, Traversier A, Barthélémy M, Hay A, Lin YP, Ferraris O, Lina B. Richard M, et al. Among authors: ferraris o. PLoS One. 2012;7(5):e33880. doi: 10.1371/journal.pone.0033880. Epub 2012 May 1. PLoS One. 2012. PMID: 22563453 Free PMC article.
Influenza viruses possess at their surface two glycoproteins, the hemagglutinin and the neuraminidase, of which the antagonistic functions have to be well balanced for the virus to grow efficiently. Ferraris et al. isolated in 2003-2004 viruses lacking both a NA gene and p …
Influenza viruses possess at their surface two glycoproteins, the hemagglutinin and the neuraminidase, of which the antagonistic functions h …
Combinatorial effect of two framework mutations (E119V and I222L) in the neuraminidase active site of H3N2 influenza virus on resistance to oseltamivir.
Richard M, Ferraris O, Erny A, Barthélémy M, Traversier A, Sabatier M, Hay A, Lin YP, Russell RJ, Lina B. Richard M, et al. Among authors: ferraris o. Antimicrob Agents Chemother. 2011 Jun;55(6):2942-52. doi: 10.1128/AAC.01699-10. Epub 2011 Mar 21. Antimicrob Agents Chemother. 2011. PMID: 21422222 Free PMC article.
Impact on antiviral resistance of E119V, I222L and R292K substitutions in influenza A viruses bearing a group 2 neuraminidase (N2, N3, N6, N7 and N9).
Gaymard A, Charles-Dufant A, Sabatier M, Cortay JC, Frobert E, Picard C, Casalegno JS, Rosa-Calatrava M, Ferraris O, Valette M, Ottmann M, Lina B, Escuret V. Gaymard A, et al. Among authors: ferraris o. J Antimicrob Chemother. 2016 Nov;71(11):3036-3045. doi: 10.1093/jac/dkw275. Epub 2016 Jul 17. J Antimicrob Chemother. 2016. PMID: 27432605
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