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Tau is essential to beta -amyloid-induced neurotoxicity.
Rapoport M, Dawson HN, Binder LI, Vitek MP, Ferreira A. Rapoport M, et al. Among authors: ferreira a. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6364-9. doi: 10.1073/pnas.092136199. Epub 2002 Apr 16. Proc Natl Acad Sci U S A. 2002. PMID: 11959919 Free PMC article.
Aβ toxicity in primary cultured neurons.
Ferreira A, Sinjoanu RC, Nicholson A, Kleinschmidt S. Ferreira A, et al. Methods Mol Biol. 2011;670:141-53. doi: 10.1007/978-1-60761-744-0_11. Methods Mol Biol. 2011. PMID: 20967589
Methods related to studying tau fragmentation.
Ferreira A, Afreen S. Ferreira A, et al. Methods Cell Biol. 2017;141:245-258. doi: 10.1016/bs.mcb.2017.06.004. Epub 2017 Jul 6. Methods Cell Biol. 2017. PMID: 28882305
The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons.
Sinjoanu RC, Kleinschmidt S, Bitner RS, Brioni JD, Moeller A, Ferreira A. Sinjoanu RC, et al. Among authors: ferreira a. Neurochem Int. 2008 Sep;53(3-4):79-88. doi: 10.1016/j.neuint.2008.06.003. Epub 2008 Jun 12. Neurochem Int. 2008. PMID: 18590784 Free PMC article.
J. Biol. Chem. 280, 31746-31753; Park, S.Y., Ferreira, A., 2005. The generation of a 17kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration. ...J. Biol. Chem. 281, 28079-28089, Kelly, B.L., Ferreira
J. Biol. Chem. 280, 31746-31753; Park, S.Y., Ferreira, A., 2005. The generation of a 17kDa neurotoxic fragment: an alte …
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