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4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
Pizzimenti S, Menegatti E, Berardi D, Toaldo C, Pettazzoni P, Minelli R, Giglioni B, Cerbone A, Dianzani MU, Ferretti C, Barrera G. Pizzimenti S, et al. Among authors: ferretti c. J Nutr Biochem. 2010 Sep;21(9):818-26. doi: 10.1016/j.jnutbio.2009.06.005. Epub 2009 Sep 3. J Nutr Biochem. 2010. PMID: 19733043
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.
Toaldo C, Pizzimenti S, Cerbone A, Pettazzoni P, Menegatti E, Daniela B, Minelli R, Giglioni B, Dianzani MU, Ferretti C, Barrera G. Toaldo C, et al. Among authors: ferretti c. J Cell Mol Med. 2010 Jun;14(6A):1347-57. doi: 10.1111/j.1582-4934.2009.00966.x. Epub 2009 Nov 13. J Cell Mol Med. 2010. PMID: 19912441 Free PMC article.
Role of 4-hydroxynonenal-protein adducts in human diseases.
Barrera G, Pizzimenti S, Ciamporcero ES, Daga M, Ullio C, Arcaro A, Cetrangolo GP, Ferretti C, Dianzani C, Lepore A, Gentile F. Barrera G, et al. Among authors: ferretti c. Antioxid Redox Signal. 2015 Jun 20;22(18):1681-702. doi: 10.1089/ars.2014.6166. Epub 2015 Jan 20. Antioxid Redox Signal. 2015. PMID: 25365742 Free article. Review.
517 results