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Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells.
Vomund AN, Zinselmeyer BH, Hughes J, Calderon B, Valderrama C, Ferris ST, Wan X, Kanekura K, Carrero JA, Urano F, Unanue ER. Vomund AN, et al. Among authors: Ferris ST. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5496-502. doi: 10.1073/pnas.1515954112. Epub 2015 Aug 31. Proc Natl Acad Sci U S A. 2015. PMID: 26324934 Free PMC article.
The pancreas anatomy conditions the origin and properties of resident macrophages.
Calderon B, Carrero JA, Ferris ST, Sojka DK, Moore L, Epelman S, Murphy KM, Yokoyama WM, Randolph GJ, Unanue ER. Calderon B, et al. Among authors: Ferris ST. J Exp Med. 2015 Sep 21;212(10):1497-512. doi: 10.1084/jem.20150496. Epub 2015 Sep 7. J Exp Med. 2015. PMID: 26347472 Free PMC article.
Notch2-dependent DC2s mediate splenic germinal center responses.
Briseño CG, Satpathy AT, Davidson JT 4th, Ferris ST, Durai V, Bagadia P, O'Connor KW, Theisen DJ, Murphy TL, Murphy KM. Briseño CG, et al. Among authors: Ferris ST. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10726-10731. doi: 10.1073/pnas.1809925115. Epub 2018 Oct 2. Proc Natl Acad Sci U S A. 2018. PMID: 30279176 Free PMC article.
Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice.
Carrero JA, McCarthy DP, Ferris ST, Wan X, Hu H, Zinselmeyer BH, Vomund AN, Unanue ER. Carrero JA, et al. Among authors: Ferris ST. Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10418-E10427. doi: 10.1073/pnas.1713543114. Epub 2017 Nov 13. Proc Natl Acad Sci U S A. 2017. PMID: 29133420 Free PMC article.
B cell antigen presentation is sufficient to drive neuroinflammation in an animal model of multiple sclerosis.
Parker Harp CR, Archambault AS, Sim J, Ferris ST, Mikesell RJ, Koni PA, Shimoda M, Linington C, Russell JH, Wu GF. Parker Harp CR, et al. Among authors: Ferris ST. J Immunol. 2015 Jun 1;194(11):5077-84. doi: 10.4049/jimmunol.1402236. Epub 2015 Apr 20. J Immunol. 2015. PMID: 25895531 Free PMC article.
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