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1954 11
1955 21
1956 16
1957 26
1958 16
1959 14
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1961 10
1962 18
1963 40
1964 47
1965 30
1966 52
1967 46
1968 69
1969 63
1970 69
1971 78
1972 106
1973 76
1974 96
1975 76
1976 60
1977 82
1978 89
1979 96
1980 79
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1982 66
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1987 89
1988 124
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1998 382
1999 373
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2008 927
2009 1075
2010 1173
2011 1359
2012 1455
2013 1691
2014 1928
2015 2035
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2024 2239
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Page 1
Definite Treatment Delay With Neoadjuvant Chemotherapy and Longitudinal Monitoring by Circulating Tumor DNA for Advanced Cervical Cancer During Pregnancy: A Case Series and Literature Review.
Zhang X, Yu H, Chen K, Ding B, Shen Y. Zhang X, et al. Cancer Rep (Hoboken). 2024 Nov;7(11):e70021. doi: 10.1002/cnr2.70021. Cancer Rep (Hoboken). 2024. PMID: 39506833 Free article. Review.
CONCLUSION: In pregnant women with advanced cervical cancer, longitudinal ctDNA monitoring might be able to evaluate maternal response to NACT and confirm if delivery delay to optimize fetal outcome would compacting the maternal outcomes or not. Cervical cancer may not tra …
CONCLUSION: In pregnant women with advanced cervical cancer, longitudinal ctDNA monitoring might be able to evaluate maternal response to NA …
Outcomes of peripartum cardiomyopathy in North Africa: insights from a single-center observational study in Tunisia.
Hammami R, Abdelhedi O, Khanfir F, Shahlaq RSO, Gargouri R, Abid L, Elleuch S, Oueslati MB, Amor HI, Derbel M, Dammak A, Safi F, Chaabene K. Hammami R, et al. BMC Pregnancy Childbirth. 2024 Nov 6;24(1):722. doi: 10.1186/s12884-024-06911-3. BMC Pregnancy Childbirth. 2024. PMID: 39506714 Free article.
Prematurity occurred in 36% of newborns, and intrauterine fetal death occurred in one pregnancy. The median follow-up was 24 months [6-144 months]. ...
Prematurity occurred in 36% of newborns, and intrauterine fetal death occurred in one pregnancy. The median follow-up was 24 months [ …
Determinants of retroplacental hematoma at the Maradi mother and child health center, Niger: a case‒control study.
Ali Z, Issoufou Harouna B, Idé Amadou H, Sayo Djibo A. Ali Z, et al. BMC Pregnancy Childbirth. 2024 Nov 6;24(1):724. doi: 10.1186/s12884-024-06927-9. BMC Pregnancy Childbirth. 2024. PMID: 39506659 Free article.
INTRODUCTION: Retroplacental hematoma is a paroxysmal accident that threatens maternal and fetal prognosis. It is a major emergency in obstetric pathology. The objective of this study was to identify the factors associated with retroplacental hematomas at the Maradi Mother …
INTRODUCTION: Retroplacental hematoma is a paroxysmal accident that threatens maternal and fetal prognosis. It is a major emergency i …
Lysosomal enzyme binding to the cation-independent mannose 6-phosphate receptor is regulated allosterically by insulin-like growth factor 2.
Bohnsack RN, Misra SK, Liu J, Ishihara-Aoki M, Pereckas M, Aoki K, Ren G, Sharp JS, Dahms NM. Bohnsack RN, et al. Sci Rep. 2024 Nov 6;14(1):26875. doi: 10.1038/s41598-024-75300-9. Sci Rep. 2024. PMID: 39505925 Free article.
The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically significant in the treatment of patients with lysosomal storage diseases because it functions in the biogenesis of lysosomes by transporting mannose 6-phosphate (M6P)-containing lysosomal enzymes to …
The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically significant in the treatment of patients with lysosomal storage …
Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease.
Yang JP, Toughiri R, Gounder AP, Scheibe D, Petrus M, Fink SJ, Vallee S, Kenniston J, Papaioannou N, Langston S, Gavva NR, Horman SR. Yang JP, et al. PLoS One. 2024 Nov 6;19(11):e0307049. doi: 10.1371/journal.pone.0307049. eCollection 2024. PLoS One. 2024. PMID: 39504332 Free article.
Induction of fetal hemoglobin (HbF) has been shown to be a viable therapeutic approach to treating sickle cell disease and potentially other beta-hemoglobinopathies. ...
Induction of fetal hemoglobin (HbF) has been shown to be a viable therapeutic approach to treating sickle cell disease and potentiall …
Genome-Wide, Non-Invasive Prenatal Testing for rare chromosomal abnormalities: A systematic review and meta-analysis of diagnostic test accuracy.
Konya M, Czimbalmos A, Loczi L, Koi T, Turan C, Nagy R, Acs N, Hegyi P, Varbiro S, Gal A. Konya M, et al. PLoS One. 2024 Nov 5;19(11):e0308008. doi: 10.1371/journal.pone.0308008. eCollection 2024. PLoS One. 2024. PMID: 39499701 Free PMC article.
One was a confirmed methodology, where only cases validated by genetic testing were considered true positives with a definite diagnosis, and the other was an extended methodology, where, in addition to cases confirmed by genetic testing, intrauterine fetal death and termin …
One was a confirmed methodology, where only cases validated by genetic testing were considered true positives with a definite diagnosis, and …
Tailoring neoadjuvant chemotherapy for a pregnant patient diagnosed with IB2 squamous cervical carcinoma.
Babkova A, Robova H, Malikova H, Drozenova J, Pichlik T, Halaska MJ, Rob L. Babkova A, et al. Gynecol Oncol Rep. 2024 Oct 16;56:101532. doi: 10.1016/j.gore.2024.101532. eCollection 2024 Dec. Gynecol Oncol Rep. 2024. PMID: 39498418 Free PMC article.
The chemotherapy agents used during treatment are known for their fetal adverse effects. The aim of the therapy is to attain full-term pregnancy while minimizing fetal toxicity and decreasing tumor size. ...
The chemotherapy agents used during treatment are known for their fetal adverse effects. The aim of the therapy is to attain f …
Development and validation of an ultrasound-based estimated fetal weight reference for Chinese twin pregnancy: a retrospective cohort study.
Yang J, Yu H, Zhao Y, Cheng Z, Du Y, Yuan P, Zhang A, Liu Y, Gong X, Yu Y, Li Y, You X, Huang N, Zhang Y, Sun X, Qi H, Li HT, Wei Y. Yang J, et al. BMC Pregnancy Childbirth. 2024 Nov 4;24(1):718. doi: 10.1186/s12884-024-06924-y. BMC Pregnancy Childbirth. 2024. PMID: 39497086 Free PMC article.
BACKGROUND: Fetal growth monitoring is important for twin pregnancies. However, there has been no clinically validated tool for monitoring fetal growth of twin pregnancies in China. ...The establishment of chorionicity-specific growth chart could reduce overdiagnosi …
BACKGROUND: Fetal growth monitoring is important for twin pregnancies. However, there has been no clinically validated tool for monit …
Rescue of a spontaneous subcapsular hepatic hematoma associated with HELLP syndrome: A case report.
Yan C, Jia Z, Liu Y, Zhou W, Zhou H. Yan C, et al. Medicine (Baltimore). 2024 Nov 1;103(44):e40285. doi: 10.1097/MD.0000000000040285. Medicine (Baltimore). 2024. PMID: 39496048 Free PMC article.
PATIENT CONCERNS: A 34-year-old woman, who underwent a cesarean section due to suspected fetal distress, developed SSHH accompanied by the potential risk of rupture and deteriorated serology within the first 24 hours after delivery. ...
PATIENT CONCERNS: A 34-year-old woman, who underwent a cesarean section due to suspected fetal distress, developed SSHH accompanied b …
Catheter ablation in a monochorionic diamniotic twin pregnancy: A case report and literature review.
Jia Y, Liao H, Hu Q, Liu H, Zeng Z, Yu H. Jia Y, et al. Medicine (Baltimore). 2024 Nov 1;103(44):e40443. doi: 10.1097/MD.0000000000040443. Medicine (Baltimore). 2024. PMID: 39495973 Free PMC article. Review.
It might be efficiently controlled through optimal treatment by a multidisciplinary team, which would effectively minimize arrhythmia risk events during pregnancy and improve maternal-fetal outcomes. Based on the patient's individual situation, radiofrequency ablation may …
It might be efficiently controlled through optimal treatment by a multidisciplinary team, which would effectively minimize arrhythmia risk e …
CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections.
Rollman TB, Berkebile ZW, Hicks DM, Hatfield JS, Chauhan P, Pravetoni M, Schleiss MR, Milligan GN, Morgan TK, Bierle CJ. Rollman TB, et al. PLoS Pathog. 2024 Nov 4;20(11):e1012515. doi: 10.1371/journal.ppat.1012515. Online ahead of print. PLoS Pathog. 2024. PMID: 39495799 Free article.
Maternal T cells likely play a critical role in preventing infection at the maternal-fetal interface and limiting spread across the placenta, but concerns exist that immune responses to infection may also cause placental dysfunction and adverse pregnancy outcomes. ...
Maternal T cells likely play a critical role in preventing infection at the maternal-fetal interface and limiting spread across the p …
Effects of Ursodeoxycholic Acid Treatment for Intrahepatic Cholestasis of Pregnancy on Maternal and Fetal Outcomes.
Iqbal M, Muhammad Z, Akhter N, Shams Alam S. Iqbal M, et al. Cureus. 2024 Oct 3;16(10):e70800. doi: 10.7759/cureus.70800. eCollection 2024 Oct. Cureus. 2024. PMID: 39493201 Free PMC article.
OBJECTIVE: The objective of this study is to investigate the impact of UDCA therapy on maternal and fetal outcomes in women with ICP. MATERIALS AND METHODS: This was a prospective observational study of 123 pregnant women with ICP, aged between 20 and 45 years who w …
OBJECTIVE: The objective of this study is to investigate the impact of UDCA therapy on maternal and fetal outcomes in women wi …
Fever in Pregnancy: A Rare Case of Listeria-Induced Chorioamnionitis.
Alhomsi S, Sawallha L, Hakmi M, Al Ibrahim A, Khayoun H, Henna N. Alhomsi S, et al. Cureus. 2024 Oct 2;16(10):e70670. doi: 10.7759/cureus.70670. eCollection 2024 Oct. Cureus. 2024. PMID: 39493188 Free PMC article.
A 27-year-old pregnant woman at 27 weeks and 3 days of gestation was admitted with a history of fever for 6 days and decreased fetal movement. Administration of broad-spectrum antibiotics initially did not improve her condition. ...
A 27-year-old pregnant woman at 27 weeks and 3 days of gestation was admitted with a history of fever for 6 days and decreased fetal
Human iPSC-derived neural stem cells displaying radial glia signature exhibit long-term safety in mice.
Luciani M, Garsia C, Beretta S, Cifola I, Peano C, Merelli I, Petiti L, Miccio A, Meneghini V, Gritti A. Luciani M, et al. Nat Commun. 2024 Nov 1;15(1):9433. doi: 10.1038/s41467-024-53613-7. Nat Commun. 2024. PMID: 39487141 Free PMC article.
In this study, we demonstrate that hiPSC-NSCs adopt a radial glia-associated signature, sharing key epigenetic and transcriptional characteristics with human fetal neural stem cells (hfNSCs) while exhibiting divergent profiles from glioblastoma stem cells. ...
In this study, we demonstrate that hiPSC-NSCs adopt a radial glia-associated signature, sharing key epigenetic and transcriptional character …
Modeling Glioma Intratumoral Heterogeneity with Primary Human Neural Stem and Progenitor Cells.
Gao D, Liu DD, Eastman AE, Womack NL, Ohene-Gambill BF, Baez M, Weissman IL. Gao D, et al. bioRxiv [Preprint]. 2024 Oct 22:2024.10.20.619254. doi: 10.1101/2024.10.20.619254. bioRxiv. 2024. PMID: 39484434 Free PMC article. Preprint.
Glioblastoma multiforme (GBM) is a deadly form of glioma notable for its significant intratumoral heterogeneity, which is believed to drive therapy resistance. GBM has been observed to mimic a neural stem cell hierarchy reminiscent of normal brain development. ...Here, we …
Glioblastoma multiforme (GBM) is a deadly form of glioma notable for its significant intratumoral heterogeneity, which is believed to drive …
Oral sildenafil versus bosentan for treatment of persistent pulmonary hypertension of the newborn: a randomized controlled trial.
Kallimath A, Deshpande S, Singh P, Garegrat R, Lakshminrusimha S, Maheshwari R, Suryawanshi P. Kallimath A, et al. BMC Pediatr. 2024 Nov 1;24(1):698. doi: 10.1186/s12887-024-05107-0. BMC Pediatr. 2024. PMID: 39487423 Free PMC article. Clinical Trial.
There is a need for research on low-cost alternative therapies for management of persistent pulmonary hypertension of the newborn (PPHN). We aimed to compare oral sildenafil and bosentan as monotherapy in the treatment of neonates with PPHN. ...
There is a need for research on low-cost alternative therapies for management of persistent pulmonary hypertension of the newborn (PP …
The clinical experience of fetoscopic repair of myelomeningocele in Taiwan: The dilemma in prenatal decision-making and first successful case.
Feng M, Chen PC, Lin GR, Lin TY, Hsieh TT, Shaw SW. Feng M, et al. Taiwan J Obstet Gynecol. 2024 Nov;63(6):904-908. doi: 10.1016/j.tjog.2024.07.018. Taiwan J Obstet Gynecol. 2024. PMID: 39482001 Free article.
Exposure of the lesion to amniotic fluid exacerbates neurological outcomes, while fetal surgery for MMC repair, now a routine practice, improves postnatal outcomes. However, Asian women and their families often find it difficult to accept prenatal defects, leading nearly a …
Exposure of the lesion to amniotic fluid exacerbates neurological outcomes, while fetal surgery for MMC repair, now a routine practic …
Retrospective evaluation of obstetric processes in patients with Familial Mediterranean Fever's disease: The three years experience of a tertiary rheumatology clinic.
Deniz R, Deniz F, Ekmen ŞA, Sevinç-Özgür D, Akkuzu G, Karaalioğlu B, Yıldırım F, İnce B, Kalkan K, Özköse GG, Bes C. Deniz R, et al. Taiwan J Obstet Gynecol. 2024 Nov;63(6):900-903. doi: 10.1016/j.tjog.2024.09.008. Taiwan J Obstet Gynecol. 2024. PMID: 39482000 Free article.
In this study, we aimed to investigate the relation between FMF and pregnancy on both maternal and fetal aspects. MATERIAL AND METHODS: In this retrospective, single-center, descriptive study we analysed total of 95 pregnancies of 40 FMF patients. ...The most important obs …
In this study, we aimed to investigate the relation between FMF and pregnancy on both maternal and fetal aspects. MATERIAL AND METHOD …
The risks of emergency C-section, infant health conditions and postpartum complications in Taiwanese primiparous women with gestational diabetes mellitus: A propensity matched cohort study.
Chiu HY, Chen HH, Wang CW, Lu H, Wu CH, Yang CC, Lee SL, Cheng-Yen Lai J. Chiu HY, et al. Taiwan J Obstet Gynecol. 2024 Nov;63(6):880-886. doi: 10.1016/j.tjog.2024.01.039. Taiwan J Obstet Gynecol. 2024. PMID: 39481996 Free article.
Women in the GDM group were more likely to undergo emergency C-section for fetal distress, uterine atony, obstructed labor, delayed delivery, failed induction of labor, and umbilical cord prolapse. ...CONCLUSION: The present study suggests that GDM is associated with incre …
Women in the GDM group were more likely to undergo emergency C-section for fetal distress, uterine atony, obstructed labor, delayed d …
Myocardial infarction in rats was alleviated by MSCs derived from the maternal segment of the human umbilical cord.
Sun S, Wang L, Tang Q, Yi J, Yu X, Cao Y, Jiang L, Liu J. Sun S, et al. Front Cell Dev Biol. 2024 Oct 16;12:1469541. doi: 10.3389/fcell.2024.1469541. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 39479514 Free PMC article.
METHODS: MSCs were isolated from 3 cm-long segments of the maternal, middle and fetal segments of the UC (maternal-MSCs, middle-MSCs and fetal-MSCs, respectively). RNA-seq was used to analyze and compare the transcriptomes. ...The therapeutic effects of MSCs derived …
METHODS: MSCs were isolated from 3 cm-long segments of the maternal, middle and fetal segments of the UC (maternal-MSCs, middle-MSCs …
Implementing telemedicine for the care of women with gestational diabetes mellitus in a rural hospital: an observational retrospective study.
Tancredi M, Chrusciel J, Zaouia S, Mergey V, Laplanche D, Sanchez S. Tancredi M, et al. BMC Health Serv Res. 2024 Oct 30;24(1):1316. doi: 10.1186/s12913-024-11726-1. BMC Health Serv Res. 2024. PMID: 39478623 Free PMC article.
Telemedicine is increasingly used for the follow-up of chronic diseases. The objective of this study was to evaluate if implementing a telemedicine solution for GDM could decrease the frequency of large for gestational age (LGA) newborns in a rural hospital. ...
Telemedicine is increasingly used for the follow-up of chronic diseases. The objective of this study was to evaluate if implementing …
Morphometric Development of Medial Surface of Cerebrum in Fetal Cadavers.
Sanli OC, Ozturk K, Dursun A, Kastamoni Y, Albay S. Sanli OC, et al. Turk Neurosurg. 2023 Dec 1. doi: 10.5137/1019-5149.JTN.44965-23.4. Online ahead of print. Turk Neurosurg. 2023. PMID: 39474948 Free article.
AIM: To investigate the morphometric and morphological development of the medial surface of the cerebrum in 40 fetal cadavers without external anomalies and pathologies between the gestational ages of 22 and 40 weeks. ...Knowledge of morphological differences in the cortex …
AIM: To investigate the morphometric and morphological development of the medial surface of the cerebrum in 40 fetal cadavers without …
Conversion therapy in advanced perihilar cholangiocarcinoma based on patient-derived organoids: A case report.
He YG, Zhang LY, Li J, Wang Z, Zhao CY, Zheng L, Huang XB. He YG, et al. World J Gastrointest Oncol. 2024 Oct 15;16(10):4274-4280. doi: 10.4251/wjgo.v16.i10.4274. World J Gastrointest Oncol. 2024. PMID: 39473955 Free PMC article.
Transarterial chemoembolization with nab-paclitaxel was used in combination with toripalimab and lenvatinib, but the levels of tumor markers including alpha fetal protein, carcinoembryonic antigen, carbohydrate antigen 15-3 and cancer antigen 125 were still raised. ...CONC …
Transarterial chemoembolization with nab-paclitaxel was used in combination with toripalimab and lenvatinib, but the levels of tumor markers …
Primary Biliary Cholangitis and Chronic Arterial Hypertension in Pregnancy.
Santos MO, Marques I, Barata C, Almeida MC. Santos MO, et al. Cureus. 2024 Sep 29;16(9):e70453. doi: 10.7759/cureus.70453. eCollection 2024 Sep. Cureus. 2024. PMID: 39473673 Free PMC article.
This case report presents a woman with a history of adverse obstetric outcomes: two pregnancies complicated by preeclampsia, resulting in a medical termination in the first and fetal demise in the second. Prior to a subsequent pregnancy, she underwent investigations for hy …
This case report presents a woman with a history of adverse obstetric outcomes: two pregnancies complicated by preeclampsia, resulting in a …
Impact of Vitamin D deficiency on immunological and metabolic responses in women with recurrent pregnancy loss: focus on VDBP/HLA-G1/CTLA-4/ENTPD1/adenosine-fetal-maternal conflict crosstalk.
Al Balawi AN, Alblwi NAN, Soliman R, El-Far AH, Hassan MG, El-Sewedy T, Ameen F, Ismail NF, Elmetwalli A. Al Balawi AN, et al. BMC Pregnancy Childbirth. 2024 Oct 29;24(1):709. doi: 10.1186/s12884-024-06914-0. BMC Pregnancy Childbirth. 2024. PMID: 39472874 Free PMC article.
This study aimed to provide insight into the immunological, genetic, and metabolic networks underlying RPL, placing a particular emphasis on the interactions between VDBP, HLA-G1, CTLA-4, ENTPD1, and adenosine-fetal-maternal conflict crosstalk. METHODS: A retrospective stu …
This study aimed to provide insight into the immunological, genetic, and metabolic networks underlying RPL, placing a particular emphasis on …
Reverse epidemiology of obesity paradox: Fact or fiction?
Kishore BK. Kishore BK. Physiol Rep. 2024 Nov;12(21):e70107. doi: 10.14814/phy2.70107. Physiol Rep. 2024. PMID: 39472276 Free PMC article. Review.
This apparently runs counter to the epidemiology of obesity, which may increase the risk for non-communicable diseases (NCDs). The scientific community is split on obesity paradox, with some supporting it, while others call it BMI paradox. ...Hence, this review presents le …
This apparently runs counter to the epidemiology of obesity, which may increase the risk for non-communicable diseases (NCDs). The sc …
Efficacy and safety of thalidomide in patients with β-thalassemia intermedia and major.
Ju W, Din G, Huang J, Zheng M, Wang X, Liu L, Wang L, Xuan S, Xiao W, Chen A. Ju W, et al. Medicine (Baltimore). 2024 Oct 25;103(43):e40328. doi: 10.1097/MD.0000000000040328. Medicine (Baltimore). 2024. PMID: 39470504 Free PMC article.

The increase in Hb levels was primarily attributed to fetal hemoglobin (HbF). After 1 month of treatment, the HbF percentage increased from a baseline of 34.04 27.58% to 56.25 28.40% (P < .001). ...Two homozygous patients who failed thalidomide treatment achieved Hb lev

The increase in Hb levels was primarily attributed to fetal hemoglobin (HbF). After 1 month of treatment, the HbF percentage increase …
Trends in maternal body mass index, macrosomia and caesarean section in first-time mothers during the pandemic: a multicentre retrospective cohort study of 12 Melbourne public hospitals.
Goldsack AJ, Marzan MB, Rolnik DL, Lindquist AC, Said JM, Palmer KR, Sheehan PM, Potenza S, Pritchard N, Whitehead CL, Ford J, Mol BW, Walker SP, Hui L. Goldsack AJ, et al. BMC Pregnancy Childbirth. 2024 Oct 28;24(1):706. doi: 10.1186/s12884-024-06908-y. BMC Pregnancy Childbirth. 2024. PMID: 39468519 Free PMC article.
Reference values of normal fetal ductus venosus Doppler flow measurements at 11-14 weeks of gestation.
Li S, Wu H, Zhu L, Li Q, Dong X. Li S, et al. PLoS One. 2024 Oct 28;19(10):e0312874. doi: 10.1371/journal.pone.0312874. eCollection 2024. PLoS One. 2024. PMID: 39466738 Free PMC article.
OBJECTIVES: To establish the reference range of normal fetal ductus venosus pulsatility index (DV PI) and ductus venosus (DV) blood flow velocity at 11-14 weeks of gestation. ...All fetuses were followed up for pregnancy outcome using the following inclusion criteria: Sing …
OBJECTIVES: To establish the reference range of normal fetal ductus venosus pulsatility index (DV PI) and ductus venosus (DV) blood f …
Pregnancy-associated triple-negative breast cancer: A case report and literature review.
Bao W, Ma X, Xue Y, Zou X, Guo Y. Bao W, et al. Medicine (Baltimore). 2024 Oct 11;103(41):e40059. doi: 10.1097/MD.0000000000040059. Medicine (Baltimore). 2024. PMID: 39465823 Free PMC article. Review.
Improving the rate of early diagnosis and using standardized and individualized comprehensive treatment plans will minimize fetal damage and improve survival and quality of life for patients....
Improving the rate of early diagnosis and using standardized and individualized comprehensive treatment plans will minimize fetal dam …
Clinical application of myofascial therapy in the treatment of postpartum pain-related functional disorders: A review.
Zhang J, Pang T, Yao J, Li A, Dong L, Wang Y, Wang Y. Zhang J, et al. Medicine (Baltimore). 2024 Oct 4;103(40):e39869. doi: 10.1097/MD.0000000000039869. Medicine (Baltimore). 2024. PMID: 39465751 Free PMC article. Review.
During pregnancy, fetal growth could lead to changes in human biomechanics. If postpartum recovery was not properly managed, it could be exacerbated, resulting in myofascial system disorders and various functional impairments. ...The mechanism of myofascial therapy
During pregnancy, fetal growth could lead to changes in human biomechanics. If postpartum recovery was not properly managed, it could …
Spontaneously Corrected Hypoplastic Left Heart: A Case Report and Exceptional Opportunity to Discuss Etiology with Novel Therapeutic Vision.
Shahidi M. Shahidi M. Arch Iran Med. 2024 Sep 1;27(9):527-529. doi: 10.34172/aim.31185. Epub 2024 Sep 1. Arch Iran Med. 2024. PMID: 39465528 Free PMC article.
Hypoplastic left heart syndrome (HLHS) is a relatively prevalent fetal echocardiography finding in complex congenital heart diseases. Current studies indicate that intrinsic and extrinsic mechanisms could be involved in the development of left heart hypoplasia. ...
Hypoplastic left heart syndrome (HLHS) is a relatively prevalent fetal echocardiography finding in complex congenital heart diseas
Efficacy of Tenofovir Disoproxil Fumarate in Preventing Vertical Transmission of Hepatitis B in Mothers with Chronic Hepatitis B: An Evidence-Based Case Report.
Felim RR, Hasan I, Nelwan EJ. Felim RR, et al. Acta Med Indones. 2024 Jul;56(3):411-418. Acta Med Indones. 2024. PMID: 39463105 Free article. Review.
The inclusion criteria used were pregnant women with chronic hepatitis B and using TDF antiviral as a transmission prevention therapy with the study design used in the form of a meta-analysis, systematic review, randomized or nonrandomized controlled trial. ...In addition, …
The inclusion criteria used were pregnant women with chronic hepatitis B and using TDF antiviral as a transmission prevention therapy
Optimal Strategies for Screening Common Birth Defects in Children of Low- and Middle-Income Countries: A Systematic Review.
Zaki U, Qazi SH, Shamim U, Fatima S, Das JK, Bhutta ZA. Zaki U, et al. Neonatology. 2024 Oct 25:1-21. doi: 10.1159/000541697. Online ahead of print. Neonatology. 2024. PMID: 39462499 Free article.
INTRODUCTION: Congenital anomalies are one of the major causes of the global burden of diseases, and low- and middle-income countries (LMICs) are disproportionately affected. ...The most common screening techniques both prenatal and postnatal included antenatal ultrasound, …
INTRODUCTION: Congenital anomalies are one of the major causes of the global burden of diseases, and low- and middle-income countries …
Tranexamic acid for postpartum bleeding: a systematic review and individual patient data meta-analysis of randomised controlled trials.
Ker K, Sentilhes L, Shakur-Still H, Madar H, Deneux-Tharaux C, Saade G, Pacheco LD, Ageron FX, Mansukhani R, Balogun E, Brenner A, Prowse D, Arribas M, Ahmadzia H, Chaudhri R, Olayemi O, Roberts I; Anti-fibrinolytics Trialists Collaborators Obstetric Group. Ker K, et al. Lancet. 2024 Oct 26;404(10463):1657-1667. doi: 10.1016/S0140-6736(24)02102-0. Lancet. 2024. PMID: 39461793 Free article.
Impact of Infections During Pregnancy on Transplacental Antibody Transfer.
Coler C, King-Nakaoka E, Every E, Chima S, Vong A, Del Rosario B, VanAbel R, Adams Waldorf KM. Coler C, et al. Vaccines (Basel). 2024 Oct 21;12(10):1199. doi: 10.3390/vaccines12101199. Vaccines (Basel). 2024. PMID: 39460363 Free PMC article. Review.
Vaccination in pregnancy is important to protect the mother and fetus from infectious diseases. The transfer of maternal antibodies across the placenta during pregnancy can continue to protect the neonate for several months after birth while the neonatal adaptive immune sy …
Vaccination in pregnancy is important to protect the mother and fetus from infectious diseases. The transfer of maternal antibodies a …
A Lipid Nanoparticle-Formulated Self-Amplifying RNA Rift Valley Fever Vaccine Induces a Robust Humoral Immune Response in Mice.
Kitandwe PK, Rogers P, Hu K, Nayebare O, Blakney AK, McKay PF, Kaleebu P, Shattock RJ. Kitandwe PK, et al. Vaccines (Basel). 2024 Sep 24;12(10):1088. doi: 10.3390/vaccines12101088. Vaccines (Basel). 2024. PMID: 39460255 Free PMC article.
Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that causes high fetal and neonatal mortality rates in ruminants and sometimes severe to fatal complications like encephalitis and hemorrhagic fever in humans. ...
Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that causes high fetal and neonatal mortality rates in ruminants and somet …
Intrauterine Fetal Demise, Spontaneous Abortion and Congenital Cytomegalovirus: A Systematic Review of the Incidence and Histopathologic Features.
Pesch MH, Mowers J, Huynh A, Schleiss MR. Pesch MH, et al. Viruses. 2024 Sep 30;16(10):1552. doi: 10.3390/v16101552. Viruses. 2024. PMID: 39459885 Free PMC article. Review.
The objective was to review the existing literature reporting on spontaneous abortion (SA) and intrauterine fetal demise (IUFD) associated with cytomegalovirus (CMV) infection. A review using standardized terminology such as 'intrauterine fetal death', 'congenital c …
The objective was to review the existing literature reporting on spontaneous abortion (SA) and intrauterine fetal demise (IUFD) assoc …
Maternal and Fetal Outcome of COVID-19 Infection among Pregnant Women.
Khalil EM, Madney YM, Hassan M, Fahmy AM, Alshammari SO, Alshammari QA, Abou-Taleb HA, Taha AA, Elgendy MO, Ali HAA. Khalil EM, et al. Medicina (Kaunas). 2024 Oct 12;60(10):1676. doi: 10.3390/medicina60101676. Medicina (Kaunas). 2024. PMID: 39459463 Free PMC article.

The number of maternal deaths in the third trimester was higher than in the first and second trimesters (16 (24.2%) vs. no deaths and 16 (24.2%) vs. 1 (4%) deaths, respectively, at p < 0.05). In terms of fetal outcomes, a good fetal condition was more likely if t

The number of maternal deaths in the third trimester was higher than in the first and second trimesters (16 (24.2%) vs. no deaths and 16 (24 …
Exploring the Father's Role in Determining Neonatal Birth Weight: A Narrative Review.
Libretti A, Savasta F, Nicosia A, Corsini C, De Pedrini A, Leo L, Laganà AS, Troìa L, Dellino M, Tinelli R, Sorrentino F, Remorgida V. Libretti A, et al. Medicina (Kaunas). 2024 Oct 10;60(10):1661. doi: 10.3390/medicina60101661. Medicina (Kaunas). 2024. PMID: 39459447 Free PMC article. Review.
It can also indicate future health challenges like asthma, cognitive impairment, and chronic diseases such as hypertension and diabetes. Nineteen publications were found through a thorough search of the Medline, PubMed, and Scopus databases, which provide insights into how …
It can also indicate future health challenges like asthma, cognitive impairment, and chronic diseases such as hypertension and diabet …
Fetal Teratomas: Advances in Diagnosis and Management.
Abiad M, Zargarzadeh N, Javinani A, Krispin E, Shamshirsaz AA. Abiad M, et al. J Clin Med. 2024 Oct 19;13(20):6245. doi: 10.3390/jcm13206245. J Clin Med. 2024. PMID: 39458194 Free PMC article. Review.
Fetal teratomas, though rare, represent a significant proportion of tumors arising during fetal development. ...Interventions such as ex-utero intrapartum treatment (EXIT) procedures and minimally invasive alternatives have emerged as critical tools to improve neona
Fetal teratomas, though rare, represent a significant proportion of tumors arising during fetal development. ...Interventions
Diagnosis, Management and Outcome of Truncus Arteriosus Communis Diagnosed during Fetal Life-Cohort Study and Systematic Literature Review.
Wittek A, Plöger R, Walter A, Strizek B, Geipel A, Gembruch U, Neubauer R, Recker F. Wittek A, et al. J Clin Med. 2024 Oct 15;13(20):6143. doi: 10.3390/jcm13206143. J Clin Med. 2024. PMID: 39458093 Free PMC article.
This defect, constituting approximately 1-4% of congenital heart diseases, poses significant challenges in prenatal diagnosis, management, and postnatal outcomes. ...The review included studies that especially described the use of fetal echocardiography, the course …
This defect, constituting approximately 1-4% of congenital heart diseases, poses significant challenges in prenatal diagnosis, manage …
Vitamin D Receptor-Interplay in COVID-19-Negative, -Infected, and -Vaccinated Women during Pregnancy.
Condac C, Lozneanu L, Matasariu DR, Ursache A, Bujor IE, Niță ME, Boiculese VL, Sava M, Țăroi P, Bîrluțiu V. Condac C, et al. J Clin Med. 2024 Oct 15;13(20):6140. doi: 10.3390/jcm13206140. J Clin Med. 2024. PMID: 39458089 Free PMC article.
Background: The trophoblast is a significant source of vitamin D synthesis during pregnancy, with the literature suggesting its role in fetal growth. We aim to underline a possible mechanism that would explain negative fetal outcomes in COVID-19-positive mothers by …
Background: The trophoblast is a significant source of vitamin D synthesis during pregnancy, with the literature suggesting its role in f
Lysteria Monocytogenes Infection during Monochorionic Twin Pregnancy: Case Report and Review of the Literature.
Roero S, Peila C, Arduino S, Deantoni S, Coscia A, Revelli A. Roero S, et al. J Clin Med. 2024 Oct 11;13(20):6061. doi: 10.3390/jcm13206061. J Clin Med. 2024. PMID: 39458011 Free PMC article. Review.
Infected women usually display aspecific and mild symptoms, and rarely develop the severe forms of the disease (such as neurolisteriosis). On the contrary, fetal and neonatal listeriosis can lead to complications such as fetal loss, preterm birth, neonatal sepsis, a …
Infected women usually display aspecific and mild symptoms, and rarely develop the severe forms of the disease (such as neurolisteriosis). O …
Phosphodiesterase Inhibitors in Fetal Growth Restriction: Do Not Forget to Consider Fetal Sex and Subcellular Compartmentation.
Peyter AC, Baud D, Tolsa JF. Peyter AC, et al. Biomedicines. 2024 Oct 14;12(10):2329. doi: 10.3390/biomedicines12102329. Biomedicines. 2024. PMID: 39457641 Free PMC article.
Fetal growth restriction (FGR) is a common complication of pregnancy, associated with major perinatal mortality and morbidity, and with an increased risk to develop cardiometabolic diseases later in life. There is currently no effective approach to prevent or treat
Fetal growth restriction (FGR) is a common complication of pregnancy, associated with major perinatal mortality and morbidity, and wi
Dyslipidemia in Pregnancy: A Systematic Review of Molecular Alterations and Clinical Implications.
Preda A, Preda SD, Mota M, Iliescu DG, Zorila LG, Comanescu AC, Mitrea A, Clenciu D, Mota E, Vladu IM. Preda A, et al. Biomedicines. 2024 Oct 3;12(10):2252. doi: 10.3390/biomedicines12102252. Biomedicines. 2024. PMID: 39457565 Free PMC article. Review.
BACKGROUND: Dyslipidemia in pregnancy presents unique clinical challenges due to its effects on maternal and fetal health. This systematic review hypothesizes that molecular alterations in lipid metabolism during pregnancy contribute to adverse pregnancy outcomes and seeks …
BACKGROUND: Dyslipidemia in pregnancy presents unique clinical challenges due to its effects on maternal and fetal health. This syste …
Non-Invasive Prenatal Screening from a Genetic Counseling Prospective: Pre and Post-Genetic Counseling Regarding Rare Chromosomal Abnormalities and Incidental Finding.
Matteo DM, Lorenzo C, Raffaele P, Carmelo P. Matteo DM, et al. Genes (Basel). 2024 Oct 21;15(10):1349. doi: 10.3390/genes15101349. Genes (Basel). 2024. PMID: 39457473 Free PMC article. Review.
BACKGROUND: Arising in the late 1990s, when a promising role in prenatal diagnostics was first delineated for circulating fetal DNA, non-invasive prenatal tests (NIPTs) have been increasingly used with more frequency and popularity. These exams have been used as a prenatal …
BACKGROUND: Arising in the late 1990s, when a promising role in prenatal diagnostics was first delineated for circulating fetal DNA, …
Risk Factors and Outcomes Associated with Pneumothorax in Very Preterm Infants.
Nogueroles Blanco C, Herranz-Barbero A, Velilla-Aparicio M, Balcells-Esponera C, Teresa-Palacio M, Alsina Casanova M, Carrasco Carrasco C, Borràs-Novell C, Rodríguez-Miguélez JM, Salvia-Roigés MD, Aldecoa-Bilbao V. Nogueroles Blanco C, et al. Children (Basel). 2024 Sep 27;11(10):1179. doi: 10.3390/children11101179. Children (Basel). 2024. PMID: 39457144 Free PMC article.
BACKGROUND/OBJECTIVES: Pneumothorax can be a major complication of neonatal lung diseases. We aim to delineate trends and describe the main outcomes related to pneumothorax in very preterm infants (VPI). ...
BACKGROUND/OBJECTIVES: Pneumothorax can be a major complication of neonatal lung diseases. We aim to delineate trends and describe th …
Dietary Regulation of Lipid Metabolism in Gestational Diabetes Mellitus: Implications for Fetal Macrosomia.
Frankevich N, Chagovets V, Tokareva A, Starodubtseva N, Limonova E, Sukhikh G, Frankevich V. Frankevich N, et al. Int J Mol Sci. 2024 Oct 19;25(20):11248. doi: 10.3390/ijms252011248. Int J Mol Sci. 2024. PMID: 39457029 Free PMC article.
The primary therapeutic approach for managing hyperglycemia today is diet therapy. Lipids are not only a source of nutrients but also play a role in initiating adipocyte differentiation in the fetus, which may explain the development of fetal macrosomia and future m …
The primary therapeutic approach for managing hyperglycemia today is diet therapy. Lipids are not only a source of nutrients but also …
Impaired Endothelium-Dependent Vasodilation and Increased Levels of Soluble Fms-like Tyrosine Kinase-1 Induced by Reduced Uterine Perfusion Pressure in Pregnant Rats: Evidence of Protective Effects with Sodium Nitrite Treatment in Preeclampsia.
Da Silva MLS, Gomes SEB, Martins LZ, Rodrigues SD, Toghi CJ, Dias-Junior CA. Da Silva MLS, et al. Int J Mol Sci. 2024 Oct 15;25(20):11051. doi: 10.3390/ijms252011051. Int J Mol Sci. 2024. PMID: 39456834 Free PMC article.
Pregnant rats submitted to the placental ischemia received saline (RUPP group) or sodium nitrite (RUPP + Na-Nitrite group). Blood pressure, placental and fetal weights, and the number of pups were recorded. Plasma levels of NO metabolites and sFlt-1 were also determined. V …
Pregnant rats submitted to the placental ischemia received saline (RUPP group) or sodium nitrite (RUPP + Na-Nitrite group). Blood pressure, …
The Role of Xanthine Oxidase in Pregnancy Complications: A Systematic Review.
Annesi L, Tossetta G, Borghi C, Piani F. Annesi L, et al. Antioxidants (Basel). 2024 Oct 14;13(10):1234. doi: 10.3390/antiox13101234. Antioxidants (Basel). 2024. PMID: 39456486 Free PMC article. Review.
We conducted systematic searches in the PubMed and Web of Science databases to identify all human studies investigating XO in pregnancy diseases up to June 2024. A total of 195 references have been identified and 14 studies were included. ...Overall, all the included studi …
We conducted systematic searches in the PubMed and Web of Science databases to identify all human studies investigating XO in pregnancy d
The Biological Effect of Enriching the Plasma Content in Platelet-Rich Plasma: An In Vitro Study.
Anitua E, Zalduendo M, Prado R, Troya M, Tierno R, de la Fuente M, Alkhraisat MH. Anitua E, et al. Biomolecules. 2024 Oct 18;14(10):1328. doi: 10.3390/biom14101328. Biomolecules. 2024. PMID: 39456261 Free PMC article.
In addition, these blood derivates have been successfully included in cell therapy as fetal bovine serum substitutes, due to the real need to avoid the risk of host immunologic reactions and the animal disease transmission associated with reagents from animal origin …
In addition, these blood derivates have been successfully included in cell therapy as fetal bovine serum substitutes, due to t …
Role of Gonadal Steroid Hormones in the Eye: Therapeutic Implications.
Valero-Ochando J, Cantó A, López-Pedrajas R, Almansa I, Miranda M. Valero-Ochando J, et al. Biomolecules. 2024 Oct 7;14(10):1262. doi: 10.3390/biom14101262. Biomolecules. 2024. PMID: 39456195 Free PMC article. Review.
Gonadal steroid hormones are critical regulatory substances involved in various developmental and physiological processes from fetal development through adulthood. These hormones, derived from cholesterol, are synthesized primarily by the gonads, adrenal cortex, and placen …
Gonadal steroid hormones are critical regulatory substances involved in various developmental and physiological processes from fetal
Prenatal exposure to per- and polyfluoroalkyl substances, fetoplacental hemodynamics, and fetal growth.
Knox B, Güil-Oumrait N, Basagaña X, Cserbik D, Dadvand P, Foraster M, Galmes T, Gascon M, Dolores Gómez-Roig M, Gómez-Herrera L, Småstuen Haug L, Llurba E, Márquez S, Rivas I, Sunyer J, Thomsen C, Julia Zanini M, Bustamante M, Vrijheid M. Knox B, et al. Environ Int. 2024 Oct 20;193:109090. doi: 10.1016/j.envint.2024.109090. Online ahead of print. Environ Int. 2024. PMID: 39454342 Free article.
Twenty-three PFAS were measured at 32 weeks of pregnancy in maternal plasma, of which 13 were present above detectable levels. Fetal growth was measured by ultrasound, as estimated fetal weight at 32 and 37 weeks of gestation, and weight at birth. ...RESULTS: Single …
Twenty-three PFAS were measured at 32 weeks of pregnancy in maternal plasma, of which 13 were present above detectable levels. Fetal
Steps Toward Decreasing Maternal Alcohol Consumption in Israel: Nationwide Trends During a Decade.
Senecky Y, Zrubavel Yaaron N, Chodick G, Berger A, Hen-Herbst L, Fund IB, Massalha M, Matot R, Ganelin-Cohen E. Senecky Y, et al. Public Health Rep. 2024 Oct 25:333549241289035. doi: 10.1177/00333549241289035. Online ahead of print. Public Health Rep. 2024. PMID: 39454030 Free article.
OBJECTIVES: Prenatal alcohol exposure poses a substantial risk to fetal development. Efforts were made in 2011-2020 to increase public awareness of and prevent alcohol consumption during pregnancy. ...
OBJECTIVES: Prenatal alcohol exposure poses a substantial risk to fetal development. Efforts were made in 2011-2020 to increase publi …
The effect of histological and subclinical chorioamnionitis and funisitis on breathing effort in premature infants at birth: a retrospective cohort study.
Panneflek TJR, Dekker J, Kuypers KLAM, van der Meeren LE, Polglase GR, Hooper SB, van den Akker T, Pas ABT. Panneflek TJR, et al. Eur J Pediatr. 2024 Dec;183(12):5497-5507. doi: 10.1007/s00431-024-05815-w. Epub 2024 Oct 25. Eur J Pediatr. 2024. PMID: 39453483 Free PMC article.
Antenatal inflammation in the form of chorioamnionitis (fetal membranes; HCA) and funisitis (umbilical vessels; FUN) is a major risk factor for preterm birth. ...WHAT IS KNOWN: Acute antenatal inflammation, in the form of chorioamnionitis (fetal membranes) and funis …
Antenatal inflammation in the form of chorioamnionitis (fetal membranes; HCA) and funisitis (umbilical vessels; FUN) is a major risk …
Transplacental Transfer of Oxytocin and Its Impact on Neonatal Cord Blood and In Vitro Retinal Cell Activity.
Adegboro CO, Luo W, Kabra M, McAdams RM, York NW, Wijenayake RI, Suchla KM, Pillers DM, Pattnaik BR. Adegboro CO, et al. Cells. 2024 Oct 19;13(20):1735. doi: 10.3390/cells13201735. Cells. 2024. PMID: 39451253 Free PMC article.
The development of fetal organs can be impacted by systemic changes in maternal circulation, with the placenta playing a pivotal role in maintaining pregnancy homeostasis and nutrient exchange. ...Human fetal RPE (hfRPE) cells treated with OXT (10 M) were assessed f …
The development of fetal organs can be impacted by systemic changes in maternal circulation, with the placenta playing a pivotal role …
Multi-Organ Phenotypes of Offspring Born Following Hypertensive Disorders of Pregnancy: A Systematic Review.
Sattwika PD, Schuermans A, Cutler HR, Alkhodari M, Anggraeni VY, Nurdiati DS, Lapidaire W, Leeson P, Lewandowski AJ. Sattwika PD, et al. J Am Heart Assoc. 2024 Nov 5;13(21):e033617. doi: 10.1161/JAHA.123.033617. Epub 2024 Oct 25. J Am Heart Assoc. 2024. PMID: 39450722 Free article.
BACKGROUND: Hypertensive pregnancies are associated with an increased risk of cardiovascular and neurological diseases in the offspring during later life. However, less is known about the potential impact on multi-organ phenotypes in offspring before disease symptoms occur …
BACKGROUND: Hypertensive pregnancies are associated with an increased risk of cardiovascular and neurological diseases in the offspri …
Upregulation of miR-6747-3p affects red blood cell lineage development and induces fetal hemoglobin expression by targeting BCL11A in beta-thalassemia.
Lv A, Chen M, Zhang S, Zhao W, Li J, Lin S, Zheng Y, Lin N, Xu L, Huang H. Lv A, et al. Mol Med Rep. 2025 Jan;31(1):7. doi: 10.3892/mmr.2024.13372. Epub 2024 Oct 25. Mol Med Rep. 2025. PMID: 39450557 Free PMC article.
Numerous miRNAs, including miR-6747-3p, are aberrantly expressed in beta-thalassemia major (beta-TM), but there are no reports on the mechanism of miR-6747-3p in regulating red blood cell lineage development and fetal hemoglobin (HbF) expression. In the present study, RT-q …
Numerous miRNAs, including miR-6747-3p, are aberrantly expressed in beta-thalassemia major (beta-TM), but there are no reports on the mechan …
Foramen Ovale Pulsatility Index as an Early Affected Doppler Study among Abnormal Growth Fetuses: A Recent Insight for Practice Based on a Prospective Study.
Faraji A, Gharibpour F, Namazi N, Shakiba AM, Kasraeian M, Asadi N, Vafaei H, Zare M, Bazrafshan K, Oveisi Z. Faraji A, et al. Iran J Med Sci. 2024 Oct 1;49(10):632-642. doi: 10.30476/ijms.2024.100177.3231. eCollection 2024 Oct. Iran J Med Sci. 2024. PMID: 39449775 Free PMC article.
BACKGROUND: Routine Doppler study is a common tool for early diagnosis of Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA) patients. It aimed to determine the role of the Foramen Ovale Pulsatility Index (FOPI) study beside routine Doppler study among pati …
BACKGROUND: Routine Doppler study is a common tool for early diagnosis of Fetal Growth Restriction (FGR) and Small for Gestational Ag …
Changes in the expression profile of serum lncRNAs in pregnant women with high hepatitis B viral load during antiviral and non-antiviral treatment.
Wang C, Liang X, Jia Z, Huang Y, Chen H, Wei H, Huang Y, Huang X, Fang X. Wang C, et al. BMC Pregnancy Childbirth. 2024 Oct 24;24(1):696. doi: 10.1186/s12884-024-06907-z. BMC Pregnancy Childbirth. 2024. PMID: 39449132 Free PMC article.
This study may provide a basis for preventing potential adverse effects of antiviral treatment on maternal and fetal health....
This study may provide a basis for preventing potential adverse effects of antiviral treatment on maternal and fetal health....
Optimizing lipid nanoparticles for fetal gene delivery in vitro, ex vivo, and aided with machine learning.
Abostait A, Abdelkarim M, Bao Z, Miyake Y, Tse WH, Di Ciano-Oliveir C, Buerki-Thurnherr T, Allen C, Keijzer R, Labouta HI. Abostait A, et al. J Control Release. 2024 Oct 27;376:678-700. doi: 10.1016/j.jconrel.2024.10.047. Online ahead of print. J Control Release. 2024. PMID: 39447842 Free article.
There is a clinical need to develop lipid nanoparticles (LNPs) to deliver congenital therapies to the fetus during pregnancy. The aim of these therapies is to restore normal fetal development and prevent irreversible conditions after birth. ...Finally, we ass …
There is a clinical need to develop lipid nanoparticles (LNPs) to deliver congenital therapies to the fetus during pregnancy. The aim …
Impact of Antiphospholipid Syndrome on Reproductive Outcomes: Current Insights and Management Approaches.
He L, Sims C. He L, et al. Semin Reprod Med. 2024 Oct 24. doi: 10.1055/s-0044-1790225. Online ahead of print. Semin Reprod Med. 2024. PMID: 39447614 Free article.
Similar to other autoimmune diseases, stable or quiescent disease and planning with a rheumatologist and obstetrician prior to conception are vital components of a successful pregnancy. ...While APS is a relatively rare condition, the effects this disease can have on mater …
Similar to other autoimmune diseases, stable or quiescent disease and planning with a rheumatologist and obstetrician prior to concep …
Gestational organophosphate pesticide exposure and childhood cardiovascular outcomes.
Stevens DR, Blaauwendraad SM, Bommarito PA, van den Dries M, Trasande L, Spaan S, Pronk A, Tiemeier H, Gaillard R, Jaddoe VWV, Ferguson KK. Stevens DR, et al. Environ Int. 2024 Oct 19;193:109082. doi: 10.1016/j.envint.2024.109082. Online ahead of print. Environ Int. 2024. PMID: 39447473 Free article.
Exposure to organophosphate pesticides during pregnancy impairs fetal development, but the potential long-term effects of gestational organophosphate pesticide exposure are less well understood. ...
Exposure to organophosphate pesticides during pregnancy impairs fetal development, but the potential long-term effects of gestational …
Factors associated with COVID-19 infection in pregnant women: Focusing on maternal anxiety.
Jeong W, Kim B, Hong SH, Cho E, Kim SY, Moon JY. Jeong W, et al. PLoS One. 2024 Oct 24;19(10):e0312300. doi: 10.1371/journal.pone.0312300. eCollection 2024. PLoS One. 2024. PMID: 39446762 Free PMC article.
Maternal depression, and posttraumatic stress disorder were significantly higher in pregnant women with COVID-19 infection, while fetal attachment showed no significant difference. Pregnant women infected with COVID-19 during pregnancy were more likely to experience anxiet …
Maternal depression, and posttraumatic stress disorder were significantly higher in pregnant women with COVID-19 infection, while fetal
Kagami-Ogata Syndrome.
Ogata T, Kagami M. Ogata T, et al. 2024 Oct 24. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2024 Oct 24. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 39446997 Free Books & Documents. Review.
MANAGEMENT: Treatment of manifestations: Developmental and educational support; mechanical ventilation and oxygen therapy as needed after birth; tracheostomy as required; monitor and treat upper and lower respiratory tract infections; treatment of scoliosis per orthopedist …
MANAGEMENT: Treatment of manifestations: Developmental and educational support; mechanical ventilation and oxygen therapy as needed a …
Analysis of Caudal Regression Syndrome: A Case Report From Bulgaria.
Gyokova E, Hristova-Atanasova E, Yesilyer M. Gyokova E, et al. Cureus. 2024 Sep 23;16(9):e69985. doi: 10.7759/cureus.69985. eCollection 2024 Sep. Cureus. 2024. PMID: 39445236 Free PMC article.
A 19-year-old G1P0 woman presented for a fetal anomaly scan at 27+6 weeks of gestation due to suspected oligohydramnios. The patient reported a history of maternal diabetes type 1 on insulin for the past 10 years. ...
A 19-year-old G1P0 woman presented for a fetal anomaly scan at 27+6 weeks of gestation due to suspected oligohydramnios. The patient …
Development, Validation, and Diagnostic Accuracy of the Fetal Lack of Responsiveness Scale for Diagnosis of Severe Perinatal Hypoxia.
Franco LC, Buitrago SM, Arbelaez I, Pinto LF, Blanco D, Pizarro MC, Santamaria L, Trillos C. Franco LC, et al. J Pregnancy. 2024 Oct 16;2024:9779831. doi: 10.1155/2024/9779831. eCollection 2024. J Pregnancy. 2024. PMID: 39444638 Free PMC article.
Background: There are limitations to predicting perinatal asphyxia, as current tools rely almost entirely on fetal cardiotocography (CTG). The fetal lack of responsiveness scale (FLORS) is a new diagnostic alternative based on the physiological phenomena associated …
Background: There are limitations to predicting perinatal asphyxia, as current tools rely almost entirely on fetal cardiotocography ( …
Mode of delivery in chorioamnionitis: impact on neonatal and maternal outcomes.
Kay VR, Liang I, Twiss J, Morais M. Kay VR, et al. BMC Pregnancy Childbirth. 2024 Oct 23;24(1):693. doi: 10.1186/s12884-024-06877-2. BMC Pregnancy Childbirth. 2024. PMID: 39443880 Free PMC article.
When compared by indication, the rate of early onset neonatal sepsis was greater in the cesarean section for abnormal fetal surveillance group compared to vaginal delivery but not in the cesarean section for other reasons group. ...CONCLUSIONS: The rate of early onset neon …
When compared by indication, the rate of early onset neonatal sepsis was greater in the cesarean section for abnormal fetal surveilla …
Pregnancy and delivery after functional hemispherectomy for Rasmussen's encephalitis: a case report.
Jost E, Merz WM, Kupczyk PA, Tascón Padrón L, Weber EC, Bien CG, Kosian P. Jost E, et al. BMC Neurol. 2024 Oct 23;24(1):410. doi: 10.1186/s12883-024-03906-7. BMC Neurol. 2024. PMID: 39443860 Free PMC article.
BACKGROUND: Rasmussen's encephalitis (RE) is a rare neurologic disorder characterized by progressive seizures and unilateral cerebral atrophy with onset during childhood and unknown etiology. When medical therapy appears refractory, surgical disconnection of the affected h …
BACKGROUND: Rasmussen's encephalitis (RE) is a rare neurologic disorder characterized by progressive seizures and unilateral cerebral atroph …
Case Report-Severe Hyponatremia at Birth in a Premature Infant.
Al-Omari L, Stranberg A, Fuenmayor MF, Jain S. Al-Omari L, et al. J Mother Child. 2024 Oct 23;28(1):83-86. doi: 10.34763/jmotherandchild.20242801.d-24-00006. eCollection 2024 Feb 1. J Mother Child. 2024. PMID: 39442071 Free PMC article.
BACKGROUND: Given the role of the placenta in maintaining maternal-fetal equilibrium, changes in maternal sodium levels affect the fetus. Clinicians must also account for the direct impact of maternal conditions and medications on the neonate. ...We speculate that severe m …
BACKGROUND: Given the role of the placenta in maintaining maternal-fetal equilibrium, changes in maternal sodium levels affect the fe …
Senescent Syncytiotrophoblast Secretion During Early Onset Preeclampsia.
Nonn O, Debnath O, Valdes DS, Sallinger K, Secener AK, Fischer C, Tiesmeyer S, Nimo J, Kuenzer T, Ulrich J, Maxian T, Knöfler M, Karau P, Bartolomaeus H, Kroneis T, Frolova A, Neuper L, Haase N, Malt A, Müller-Bötticher N, Kräker K, Kedziora S, Forstner D, Eils R, Schmidt-Ullrich R, Haider S, Verlohren S, Stern C, Sugulle M, Jones S, Thilaganathan B, Kaitu'u-Lino TJ, Tong S, Huppertz B, El-Heliebi A, Staff AC, Coscia F, Müller DN, Dechend R, Gauster M, Ishaque N, Herse F. Nonn O, et al. Hypertension. 2024 Oct 23. doi: 10.1161/HYPERTENSIONAHA.124.23362. Online ahead of print. Hypertension. 2024. PMID: 39440423 Free article.
BACKGROUND: Preeclampsia is a severe hypertensive disorder in pregnancy that causes preterm delivery, maternal and fetal morbidity, mortality, and life-long sequelae. Understanding the pathogenesis of preeclampsia is a critical first step toward protecting mother and child …
BACKGROUND: Preeclampsia is a severe hypertensive disorder in pregnancy that causes preterm delivery, maternal and fetal morbidity, m …
Prolonged transcranial magnetic stimulation in a pregnant patient with treatment-resistant depression: a case report.
Jawish R, Smid M, Gordon A, Shangraw K, Mickey BJ. Jawish R, et al. J Med Case Rep. 2024 Oct 23;18(1):512. doi: 10.1186/s13256-024-04855-y. J Med Case Rep. 2024. PMID: 39438948 Free PMC article.
The patient had previously trialed psychotherapy, multiple antidepressants, and mood stabilizers and had achieved remission with lithium prior to pregnancy. Due to pregnancy and fetal safety concerns, the patient discontinued lithium and consequently suffered progressive w …
The patient had previously trialed psychotherapy, multiple antidepressants, and mood stabilizers and had achieved remission with lithium pri …
Single-cell multi-modal integrative analyses highlight functional dynamic gene regulatory networks directing human cardiac development.
Holman AR, Tran S, Destici E, Farah EN, Li T, Nelson AC, Engler AJ, Chi NC. Holman AR, et al. Cell Genom. 2024 Oct 16:100680. doi: 10.1016/j.xgen.2024.100680. Online ahead of print. Cell Genom. 2024. PMID: 39437788 Free article.
Illuminating the precise stepwise genetic programs directing cardiac development provides insights into the mechanisms of congenital heart disease and strategies for cardiac regenerative therapies. Here, we integrate in vitro and in vivo human single-cell multi-omic studie …
Illuminating the precise stepwise genetic programs directing cardiac development provides insights into the mechanisms of congenital heart d …
On placental and lactational transfer of IgG-based therapeutic proteins - Current understanding and knowledge gaps from a clinical pharmacology perspective.
Guinn D, Kratz K, Baisden K, Ridge S, McClymont S, Fletcher EP, Johnson T, Wang YM. Guinn D, et al. Clin Transl Sci. 2024 Oct;17(10):e70049. doi: 10.1111/cts.70049. Clin Transl Sci. 2024. PMID: 39436322 Free PMC article. Review.
We describe the known mechanisms of placental or lactational transfer of IgG-based therapeutic proteins and use clinical examples to highlight the potential for fetal or infant exposure during pregnancy and lactation. Placental transfer of IgG-based therapeutic proteins ma …
We describe the known mechanisms of placental or lactational transfer of IgG-based therapeutic proteins and use clinical examples to highlig …
Development of a humanized mouse model with functional human materno-fetal interface immunity.
Dong S, Fu C, Shu C, Xie M, Li Y, Zou J, Meng YZ, Xu P, Shan YH, Tian HM, He J, Yang YG, Hu Z. Dong S, et al. JCI Insight. 2024 Oct 22;9(20):e176527. doi: 10.1172/jci.insight.176527. JCI Insight. 2024. PMID: 39435662 Free PMC article.
Materno-fetal immunity possesses specialized characteristics to ensure pathogen clearance while maintaining tolerance to the semiallogeneic fetus. ...Collectively, these results demonstrate that the pregnant HIS mouse model permits the development of functional human mater …
Materno-fetal immunity possesses specialized characteristics to ensure pathogen clearance while maintaining tolerance to the semiallo …
Guillain-Barré syndrome in pregnancy: a case report and review of the literature.
Iliadi-Tulbure C, Cemortan M, Jubirca S, Cospormac V, Bubulici C, Vicol MM. Iliadi-Tulbure C, et al. AJOG Glob Rep. 2024 Sep 14;4(4):100396. doi: 10.1016/j.xagr.2024.100396. eCollection 2024 Nov. AJOG Glob Rep. 2024. PMID: 39434812 Free PMC article.
The paravertebral radicular type pains were difficult to manage with administered analgesic therapy, and there was a progression of the bulbar syndrome. Treatment with intravenous immunoglobulin was initiated. ...Guillain-Barre syndrome is a rare condition that occurs duri …
The paravertebral radicular type pains were difficult to manage with administered analgesic therapy, and there was a progression of t …
Unexplored topics in intrahepatic cholestasis of pregnancy: A review and bibliometric analysis.
Hu Q, Yu H. Hu Q, et al. Medicine (Baltimore). 2024 Oct 18;103(42):e39972. doi: 10.1097/MD.0000000000039972. Medicine (Baltimore). 2024. PMID: 39432639 Free PMC article. Review.
The Imperial College London ranked first with respect to publication output on ICP and betweenness centrality. The Journal of Maternal-Fetal & Neonatal Medicine was the journal with the highest plurality of papers. Authors such as Williamson, Beuers, Ulrich, and Shao w …
The Imperial College London ranked first with respect to publication output on ICP and betweenness centrality. The Journal of Maternal-Fe
Double umbilical artery converging into a single umbilical artery: A case report.
Yang C, Yang X, Qiu L, Liu Z. Yang C, et al. Medicine (Baltimore). 2024 Oct 18;103(42):e40199. doi: 10.1097/MD.0000000000040199. Medicine (Baltimore). 2024. PMID: 39432598 Free PMC article.
RATIONALE: The normal structure and Doppler parameters of the umbilical cord are closely related to many diseases, including fetal infection, chromosomal abnormalities, hypoxia, and growth and development restrictions. ...The patient underwent 2 ultrasound examinati …
RATIONALE: The normal structure and Doppler parameters of the umbilical cord are closely related to many diseases, including fetal
Intrapartum Ultrasound Guidance to Make Safer Any Obstetric Intervention: Fetal Head Rotation, Assisted Vaginal Birth, Breech Delivery of the Second Twin.
Dall'Asta A, Melito C, Ghi T. Dall'Asta A, et al. Clin Obstet Gynecol. 2024 Dec 1;67(4):730-738. doi: 10.1097/GRF.0000000000000891. Epub 2024 Oct 18. Clin Obstet Gynecol. 2024. PMID: 39431493 Free PMC article. Review.
Evidence from the literature supports the role of intrapartum US in predicting the outcome of labor in women diagnosed with slow progress during the first and second stage of labor, and randomized data have demonstrated that transabdominal US is far more accurate than digital exa …
Evidence from the literature supports the role of intrapartum US in predicting the outcome of labor in women diagnosed with slow progress du …
Exploring the role of endoplasmic reticulum stress in recurrent spontaneous abortion: Identification of diagnostic biomarkers and immune cell interactions.
Tang T, Fu J, Zhang C, Wang X, Cao H, Chen L. Tang T, et al. Heliyon. 2024 Oct 5;10(19):e38964. doi: 10.1016/j.heliyon.2024.e38964. eCollection 2024 Oct 15. Heliyon. 2024. PMID: 39430538 Free PMC article.
Dysregulated endoplasmic reticulum stress (ERS) is associated with recurrent spontaneous abortion (RSA) and is involved in the mechanisms that govern immune balance and vascular regulation at the maternal-fetal interface. The molecular intricacies of these mechanisms remai …
Dysregulated endoplasmic reticulum stress (ERS) is associated with recurrent spontaneous abortion (RSA) and is involved in the mechanisms th …
Establishment of lung cancer cell lines and tumorigenesis in mice from malignant pleural effusion in patients with lung cancer.
Kanaji N, Yokohira M, Inoue T, Watanabe N, Mizoguchi H, Komori Y, Kawada K, Kadowaki N. Kanaji N, et al. Transl Lung Cancer Res. 2024 Sep 30;13(9):2340-2351. doi: 10.21037/tlcr-24-143. Epub 2024 Sep 25. Transl Lung Cancer Res. 2024. PMID: 39430339 Free PMC article.
METHODS: Cells derived from 5 mL of MPE were cultured in several conditions, including 100% MPE supernatant and Roswell Park Memorial Institute-1640 supplemented with 10% fetal bovine serum (FBS) or 10% MPE supernatant. When steady cell growth was observed, fewer cells wer …
METHODS: Cells derived from 5 mL of MPE were cultured in several conditions, including 100% MPE supernatant and Roswell Park Memorial Instit …
detectCilia: An R Package for Automated Detection and Length Measurement of Primary Cilia.
Budde-Sagert K, Krueger S, Sehlke C, Lemcke H, Jonitz-Heincke A, David R, Bader R, Uhrmacher AM. Budde-Sagert K, et al. Bioinform Biol Insights. 2024 Oct 18;18:11779322241280431. doi: 10.1177/11779322241280431. eCollection 2024. Bioinform Biol Insights. 2024. PMID: 39430098 Free PMC article.
These media compositions include (1) insulin-transferrin-selenium (ITS); (2) ITS and dexamethasone (Dexa); (3) ITS, Dexa, insulin-like growth factor 1 (IGF-1), and transforming growth factor beta 1 (TGF-beta1); and (4) fetal bovine serum (FBS). RESULTS: The assessment of d …
These media compositions include (1) insulin-transferrin-selenium (ITS); (2) ITS and dexamethasone (Dexa); (3) ITS, Dexa, insulin-like growt …
Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice.
Gilley SP, Ruebel ML, Chintapalli SV, Wright CJ, Rozance PJ, Shankar K. Gilley SP, et al. Front Endocrinol (Lausanne). 2024 Oct 4;15:1423464. doi: 10.3389/fendo.2024.1423464. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39429739 Free PMC article.
BACKGROUND: Maternal undernutrition is the most common cause of fetal growth restriction (FGR) worldwide. FGR increases morbidity and mortality during infancy, as well as contributes to adult-onset diseases including obesity and type 2 diabetes. ...
BACKGROUND: Maternal undernutrition is the most common cause of fetal growth restriction (FGR) worldwide. FGR increases morbidity and …
Treatment of Galen Vein Arteriovenous Malformation with Gamma Knife Surgery.
Kuzucu P, Sözer A, Börcek AÖ. Kuzucu P, et al. Neurol India. 2024 Sep 1;72(5):1092-1094. doi: 10.4103/neurol-india.ni_954_22. Epub 2024 Oct 19. Neurol India. 2024. PMID: 39428789 Free article.
The vein of Galen arteriovenous malformation is a rare abnormality of the fetal cerebral vascular system. It is caused by the persistence of a cerebral arteriovenous fistula of the median prosencephalic vein. ...Gamma knife therapy, which is a more convenient and ef …
The vein of Galen arteriovenous malformation is a rare abnormality of the fetal cerebral vascular system. It is caused by the persist …
Maternal, Fetal, and Labour Outcomes of Dupilumab Use for Atopic Dermatitis During Pregnancy: A Systematic Review.
Chopra CR, Sharma M, Gill MS, Del Balso V, Sakka N, Abu-Hilal M. Chopra CR, et al. J Cutan Med Surg. 2024 Oct 20:12034754241290806. doi: 10.1177/12034754241290806. Online ahead of print. J Cutan Med Surg. 2024. PMID: 39428630 Free article. Review.
We conducted a systematic review to review and analyze maternal, fetal, and labour outcomes in patients receiving dupilumab for atopic dermatitis during pregnancy. ...The majority of births occurred at full term (82.5%), with a mean gestational age of 38.4 weeks. Fetal
We conducted a systematic review to review and analyze maternal, fetal, and labour outcomes in patients receiving dupilumab for atopi …
Gene expression profiles in placenta and their association with anesthesia, delivery mode and maternal diabetes.
Aljani B, Garbe AI, Sedlmeier EM, Lickert R, Rost F, Ziegler AG, Bonifacio E, Eugster A. Aljani B, et al. Placenta. 2024 Oct 15;158:126-135. doi: 10.1016/j.placenta.2024.10.008. Online ahead of print. Placenta. 2024. PMID: 39427562 Free article.
INTRODUCTION: Fetal development is dependent on placenta and affected by multiple factors including maternal diabetes. ...METHODS: Placental RNAseq transcriptome analyses were performed on maternally-derived decidua and fetal-derived villous tissue from pregnancies …
INTRODUCTION: Fetal development is dependent on placenta and affected by multiple factors including maternal diabetes. ...METHODS: Pl …
Carisoprodol Therapy and CYP2C19 Genotype.
Dean L, Kane M. Dean L, et al. 2017 Apr 4 [updated 2024 Oct 21]. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–. 2017 Apr 4 [updated 2024 Oct 21]. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–. PMID: 28520382 Free Books & Documents. Review.
Decades of clinical use have not identified a risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes associated with carisoprodol (1)....
Decades of clinical use have not identified a risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes a …
A novel frameshift deletion variant of ARSL associated with X-linked recessive chondrodysplasia punctata 1: a case report and literature review of prenatal, confirmed cases.
Zhou L, Peng Y, Chen J, Xi H, Wang S, Kang G, Tang W, Xie W. Zhou L, et al. BMC Med Genomics. 2024 Oct 18;17(1):253. doi: 10.1186/s12920-024-02029-9. BMC Med Genomics. 2024. PMID: 39425194 Free PMC article. Review.
CASE PRESENTATION: A G1P0 woman in her 30s with an unremarkable prenatal course presented in the second trimester. Maternal diseases, tobacco, alcohol, and drug history during pregnancy were denied. Obstetrical ultrasound examination revealed a flattened nose and a flatten …
CASE PRESENTATION: A G1P0 woman in her 30s with an unremarkable prenatal course presented in the second trimester. Maternal diseases, …
Toll-like receptors ligand immunomodulators for the treatment congenital diaphragmatic hernia.
Vallejo-Cremades M, Merino J, Carmona R, Córdoba L, Salvador B, Martínez L, Tovar JA, Llamas MÁ, Muñoz-Chápuli R, Fresno M. Vallejo-Cremades M, et al. Orphanet J Rare Dis. 2024 Oct 18;19(1):386. doi: 10.1186/s13023-024-03384-7. Orphanet J Rare Dis. 2024. PMID: 39425191 Free PMC article.
Unfortunately, there is no established therapy for CDH. Retinoic acid pathways are implicated in the ethology of CDH and macrophages are known to play a role in repairing organ damage. ...
Unfortunately, there is no established therapy for CDH. Retinoic acid pathways are implicated in the ethology of CDH and macrophages …
Safety of hepatitis E vaccine in pregnancy: an emulated target trial following a mass reactive vaccination campaign in Bentiu internally displaced persons camp, South Sudan.
Nesbitt RC, Azman AS, Asilaza VK, Edwards JK, Gitahi P, Nkemenang P, Duncker J, Haile M, Gakima P, Wamala JF, Loro FB, Biem D, Staderini N, Albela M, Rull M, Rumunu J, Ciglenecki I, Gignoux E. Nesbitt RC, et al. Lancet Glob Health. 2024 Nov;12(11):e1881-e1890. doi: 10.1016/S2214-109X(24)00321-8. Lancet Glob Health. 2024. PMID: 39424575 Free PMC article.
BACKGROUND: Epidemic forms of hepatitis E cause high mortality among pregnant people, with case fatality risks over 30% and adverse fetal outcomes. In 2022, the first mass reactive vaccination campaign against hepatitis E was conducted in South Sudan with the HEV239 vaccin …
BACKGROUND: Epidemic forms of hepatitis E cause high mortality among pregnant people, with case fatality risks over 30% and adverse fetal
Association of Prepregnancy Cardiometabolic Health With Hypertensive Disorders of Pregnancy Among Historically Underrepresented Groups in the United States.
Kwapong YA, Boyer T, Adebowale O, Ogunwole SM, Vaught AJ, Ndumele CE, Hays AG, Blumenthal RS, Michos ED, Selvin E, Coresh J, Minhas AS. Kwapong YA, et al. J Am Heart Assoc. 2024 Nov 5;13(21):e035526. doi: 10.1161/JAHA.124.035526. Epub 2024 Oct 18. J Am Heart Assoc. 2024. PMID: 39424428 Free article.
Modelling the maternal-fetal interface: An in vitro approach to investigate nutrient and drug transport across the human placenta.
Fuenzalida B, Basler V, Koechli N, Yi N, Staud F, Albrecht C. Fuenzalida B, et al. J Cell Mol Med. 2024 Oct;28(20):e70151. doi: 10.1111/jcmm.70151. J Cell Mol Med. 2024. PMID: 39422159 Free PMC article.
The placenta plays a critical role in maternal-fetal nutrient transport and fetal protection against drugs. Creating physiological in vitro models to study these processes is crucial, but technically challenging. ...It represents a powerful tool to study nutrient an …
The placenta plays a critical role in maternal-fetal nutrient transport and fetal protection against drugs. Creating physiolog …
Understanding external carotid artery collateralisation after cerebral revascularisation in moyamoya disease: insights from quantitative analysis.
Li W, Zhao M, Liu X, Wang P, Zhu H, Zhang Q, Zhu C, Zhang Q, Ye X, Zhao J, Zhang Y. Li W, et al. Stroke Vasc Neurol. 2024 Oct 17:svn-2024-003336. doi: 10.1136/svn-2024-003336. Online ahead of print. Stroke Vasc Neurol. 2024. PMID: 39419607 Free article.
However, no significant correlation was observed between the intracranial ARV and the modified Rankin Scale scores. Patients with fetal-type posterior cerebral arteries exhibited greater intracranial ARV compared with those without (p=0.003). ...
However, no significant correlation was observed between the intracranial ARV and the modified Rankin Scale scores. Patients with fetal
Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation.
Diemer EW, Tuhkanen J, Sammallahti S, Heinonen K, Neumann A, Robinson SL, Suderman M, Jin J, Page CM, Fore R, Rifas-Shiman SL, Oken E, Perron P, Bouchard L, Hivert MF, Räikköne K, Lahti J, Yeung EH, Guan W, Mumford SL, Magnus MC, Håberg S, Nystad W, Parr CL, London SJ, Felix JF, Tiemeier H. Diemer EW, et al. Epigenetics. 2024 Dec;19(1):2413815. doi: 10.1080/15592294.2024.2413815. Epub 2024 Oct 17. Epigenetics. 2024. PMID: 39418282 Free PMC article.
Associations between maternal vitamin D and offspring DNA methylation, adjusted for fetal sex, maternal smoking, maternal age, maternal pre-pregnancy or early pregnancy BMI, maternal education, gestational age at measurement of 25(OH)D, parity, and cell type composition, w …
Associations between maternal vitamin D and offspring DNA methylation, adjusted for fetal sex, maternal smoking, maternal age, matern …
The evolving hematopoietic niche during development.
Sánchez-Lanzas R, Jiménez-Pompa A, Ganuza M. Sánchez-Lanzas R, et al. Front Mol Biosci. 2024 Oct 2;11:1488199. doi: 10.3389/fmolb.2024.1488199. eCollection 2024. Front Mol Biosci. 2024. PMID: 39417006 Free PMC article. Review.
HSCs undergo a complex journey first migrating to the fetal liver (FL) and from there to the fetal bone marrow (FBM), where they mostly remain during adult life. ...Developing a comprehensive picture on these processes is critical to understand the earliest origins …
HSCs undergo a complex journey first migrating to the fetal liver (FL) and from there to the fetal bone marrow (FBM), where th …
Prenatal Vitamin D Deficiency and Maternal and Fetal Health Outcomes.
Tsenkova-Toncheva L, Hristova-Atanasova E, Iskrov G, Stefanov R. Tsenkova-Toncheva L, et al. Cureus. 2024 Sep 16;16(9):e69508. doi: 10.7759/cureus.69508. eCollection 2024 Sep. Cureus. 2024. PMID: 39416583 Free PMC article. Review.
We analyzed the association between prenatal VDD and maternal and fetal health outcomes by reviewing studies conducted in Europe. The literature was searched for articles published in the last 10 years focusing on preeclampsia, gestational diabetes mellitus, preterm birth, …
We analyzed the association between prenatal VDD and maternal and fetal health outcomes by reviewing studies conducted in Europe. The …
Targeted management of coexistent severe thrombophilias-A case report of a successful pregnancy despite paroxysmal nocturnal hemoglobinuria and hereditary protein C deficiency.
Dereme J, Goodyer M, Baud D, Alberio L, Grandoni F, Gavillet M. Dereme J, et al. EJHaem. 2024 Jul 11;5(5):1048-1052. doi: 10.1002/jha2.972. eCollection 2024 Oct. EJHaem. 2024. PMID: 39415927 Free PMC article.
The pregnancy progressed without thrombotic complications or breakthrough hemolysis, and the patient delivered a healthy newborn at 36 WG after induction of labor due to restricted fetal growth. To the best of our knowledge, this is the first reported case of a positive pr …
The pregnancy progressed without thrombotic complications or breakthrough hemolysis, and the patient delivered a healthy newborn at 36 WG af …
Maternal e-cigarette exposure alters DNA methylome, site-specific CpG and CH methylation, and transcriptomic signatures in the neonatal brain.
Walayat A, Hosseini M, Nepal C, Li Y, Chen W, Chen Z, Huang X, Shao XM, Zhang L, Wang C, Xiao D. Walayat A, et al. Sci Rep. 2024 Oct 16;14(1):24263. doi: 10.1038/s41598-024-75986-x. Sci Rep. 2024. PMID: 39414906 Free PMC article.
Maternal use of e-cigarette (e-cig) aerosols poses significant risks to fetal brain development, potentially increasing susceptibility to neurodevelopmental disorders in later life. ...This study aimed to understand the effects of fetal e-cig exposure on DNA methylo …
Maternal use of e-cigarette (e-cig) aerosols poses significant risks to fetal brain development, potentially increasing susceptibilit …
Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease.
Lessard S, Rimmelé P, Ling H, Moran K, Vieira B, Lin YD, Rajani GM, Hong V, Reik A, Boismenu R, Hsu B, Chen M, Cockroft BM, Uchida N, Tisdale J, Alavi A, Krishnamurti L, Abedi M, Galeon I, Reiner D, Wang L, Ramezi A, Rendo P, Walters MC, Levasseur D, Peters R, Harris T, Hicks A. Lessard S, et al. Sci Rep. 2024 Oct 16;14(1):24298. doi: 10.1038/s41598-024-74716-7. Sci Rep. 2024. PMID: 39414860 Free PMC article. Clinical Trial.
BIVV003 is a gene-edited autologous cell therapy in clinical development for the potential treatment of sickle cell disease (SCD). ...Our data suggest BIVV003 represents a compelling and novel cell therapy for the potential treatment of SCD....
BIVV003 is a gene-edited autologous cell therapy in clinical development for the potential treatment of sickle cell disease (SCD). .. …
Internet-Based Abnormal Chromosomal Diagnosis During Pregnancy Using a Noninvasive Innovative Approach to Detecting Chromosomal Abnormalities in the Fetus: Scoping Review.
Oyovwi MOS, Ohwin EP, Rotu RA, Olowe TG. Oyovwi MOS, et al. JMIR Bioinform Biotechnol. 2024 Oct 16;5:e58439. doi: 10.2196/58439. JMIR Bioinform Biotechnol. 2024. PMID: 39412876 Free PMC article. Review.
METHODS: A thorough review of existing literature and research on chromosomal abnormalities and noninvasive approaches to prenatal diagnosis and therapy was conducted. Electronic databases such as PubMed, Google Scholar, ScienceDirect, CENTRAL, CINAHL, Embase, OVID MEDLINE …
METHODS: A thorough review of existing literature and research on chromosomal abnormalities and noninvasive approaches to prenatal diagnosis …
Emergency Care Use During Pregnancy and Severe Maternal Morbidity.
Declercq ER, Liu CL, Cabral HJ, Amutah-Onukagha N, Diop H, Mehta PK. Declercq ER, et al. JAMA Netw Open. 2024 Oct 1;7(10):e2439939. doi: 10.1001/jamanetworkopen.2024.39939. JAMA Netw Open. 2024. PMID: 39412800 Free article.
Pregnant individuals experiencing births or fetal deaths during the study period were included. Data analysis was conducted from June 2022 to September 2024. ...The algorithm includes 20 conditions or procedures (excluding transfusion) identified through International Clas …
Pregnant individuals experiencing births or fetal deaths during the study period were included. Data analysis was conducted from June …
Prevalence of intestinal parasitic infections among the pregnant women in South and South East Asian countries: A systematic review and meta-analysis.
Garg S, Garg A, Ravishankar N, Garg V. Garg S, et al. Trop Parasitol. 2024 Jul-Dec;14(2):71-83. doi: 10.4103/tp.tp_7_23. Epub 2024 Sep 3. Trop Parasitol. 2024. PMID: 39411674 Free PMC article. Review.
Despite posing a potential threat to maternal and fetal health, there is limited data available on the actual burden of IPI among pregnant women. ...Considering the high burden of IPI in pregnant women as estimated in our review and the already established impact of IPI in …
Despite posing a potential threat to maternal and fetal health, there is limited data available on the actual burden of IPI among pre …
An improved high-resolution method for quantitative separation of empty and filled AAV8 capsids by strong anion exchange HPLC.
Schrecke S, McManus K, Moshfegh C, Stone J, Nguyen TU, Rivas G, Muhamed I, Mitchell DAJ. Schrecke S, et al. Front Bioeng Biotechnol. 2024 Oct 1;12:1436857. doi: 10.3389/fbioe.2024.1436857. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 39411057 Free PMC article.
Cell and gene therapy (CGT) is a field of therapeutic medicine that aims to treat, prevent, and cure diseases using engineered cells (stem cells, immune cells, and differentiated adult or fetal cells), vectors [Adeno Associated Virus (AAV), Adeno Virus (AV), …
Cell and gene therapy (CGT) is a field of therapeutic medicine that aims to treat, prevent, and cure diseases using engineered …
Impact of the 2023 ACR/EULAR Classification Criteria in Women with Primary Antiphospholipid Syndrome during Pregnancy.
Martínez-Taboada VM, Gómez AM, Del Barrio-Longarela S, Merino A, Comins-Boo A, López-Hoyos M, Riancho-Zarrabeitia L, Gálvez R, Hernández JL. Martínez-Taboada VM, et al. Diagnostics (Basel). 2024 Sep 28;14(19):2162. doi: 10.3390/diagnostics14192162. Diagnostics (Basel). 2024. PMID: 39410566 Free PMC article.
Methods: Retrospective cohort study of 93 consecutive pregnant women attending the Autoimmune Diseases Pregnancy Clinic, a multidisciplinary unit of a tertiary care teaching hospital, between 2005 and 2023. ...Women diagnosed with rheumatic autoimmune diseases other …
Methods: Retrospective cohort study of 93 consecutive pregnant women attending the Autoimmune Diseases Pregnancy Clinic, a multidisci …
Comparative Analysis of Serum and Serum-Free Medium Cultured Mesenchymal Stromal Cells for Cartilage Repair.
Kang M, Yang Y, Zhang H, Zhang Y, Wu Y, Denslin V, Othman RB, Yang Z, Han J. Kang M, et al. Int J Mol Sci. 2024 Oct 2;25(19):10627. doi: 10.3390/ijms251910627. Int J Mol Sci. 2024. PMID: 39408956 Free PMC article.
Mesenchymal stromal cells (MSCs) are promising candidates for cartilage repair therapy due to their self-renewal, chondrogenic, and immunomodulatory capacities. It is widely recognized that a shift from fetal bovine serum (FBS)-containing medium toward a fully chemi …
Mesenchymal stromal cells (MSCs) are promising candidates for cartilage repair therapy due to their self-renewal, chondrogenic, and i …
Normalization of Fetal Cerebral and Hepatic Iron by Parental Iron Therapy to Pregnant Rats with Systemic Iron Deficiency without Anemia.
Burkhart A, Johnsen KB, Skjørringe T, Nielsen AH, Routhe LJ, Hertz S, Møller LB, Thomsen LL, Moos T. Burkhart A, et al. Nutrients. 2024 Sep 27;16(19):3264. doi: 10.3390/nu16193264. Nutrients. 2024. PMID: 39408231 Free PMC article.
CONCLUSIONS: In conclusion, administering FDI subcutaneously to ID pregnant rats on E0 normalizes fetal cerebral and hepatic Fe. When applied at later gestational ages, supplementation with additional Fe to the offspring is needed to normalize cerebral and hepatic Fe....
CONCLUSIONS: In conclusion, administering FDI subcutaneously to ID pregnant rats on E0 normalizes fetal cerebral and hepatic Fe. When …
Does Insulin Treatment Affect Umbilical Artery Doppler Indices in Pregnancies Complicated by Gestational Diabetes?
Troìa L, Ferrari S, Dotta A, Giacomini S, Mainolfi E, Spissu F, Tivano A, Libretti A, Surico D, Remorgida V. Troìa L, et al. Healthcare (Basel). 2024 Oct 3;12(19):1972. doi: 10.3390/healthcare12191972. Healthcare (Basel). 2024. PMID: 39408152 Free PMC article.
The impact of increased maternal blood glucose on fetoplacental hemodynamics is not fully elucidated, especially in patients with uncontrolled GDM necessitating insulin therapy. The objective of this study was to assess the impact of insulin therapy on the umbilical …
The impact of increased maternal blood glucose on fetoplacental hemodynamics is not fully elucidated, especially in patients with uncontroll …
Estetrol Inhibits the Prostate Cancer Tumor Stimulators FSH and IGF-1.
Coelingh Bennink HJT, Roos EPM, van Moorselaar RJA, van Melick HHE, Somford DM, Roeleveld TA, de Haan TD, Reisman Y, Schultz IJ, Krijgh J, Debruyne FMJ. Coelingh Bennink HJT, et al. J Clin Med. 2024 Oct 8;13(19):5996. doi: 10.3390/jcm13195996. J Clin Med. 2024. PMID: 39408055 Free PMC article.
Background: The co-treatment of androgen deprivation therapy (ADT) for advanced prostate cancer (PCa) with the fetal estrogen estetrol (E4) may further inhibit endocrine PCa tumor stimulators. ...
Background: The co-treatment of androgen deprivation therapy (ADT) for advanced prostate cancer (PCa) with the fetal estrogen …
Conservative treatment of cesarean scar pregnancy with the combination of methotrexate and mifepristone: A systematic review.
Stabile G, Vona L, Carlucci S, Zullo F, Laganà AS, Etrusco A, Restaino S, Nappi L. Stabile G, et al. Womens Health (Lond). 2024 Jan-Dec;20:17455057241290424. doi: 10.1177/17455057241290424. Womens Health (Lond). 2024. PMID: 39407415 Free PMC article. Review.
OBJECTIVE: The purpose of this study was to evaluate the safety, the risks and effectiveness of medical therapy with methotrexate and mifepristone to better understand its role in CSP therapy. ...Unrecognized CSP has the potential to cause both fetal and mate …
OBJECTIVE: The purpose of this study was to evaluate the safety, the risks and effectiveness of medical therapy with methotrexate and …
Prenatal alcohol exposure and associations with physical size, dysmorphology and neurodevelopment: a systematic review and meta-analysis.
Akison LK, Hayes N, Vanderpeet C, Logan J, Munn Z, Middleton P, Moritz KM, Reid N; Australian FASD Guidelines Development Group, on behalf of the Australian FASD Guidelines Consortium. Akison LK, et al. BMC Med. 2024 Oct 15;22(1):467. doi: 10.1186/s12916-024-03656-w. BMC Med. 2024. PMID: 39407296 Free PMC article.
BACKGROUND: Fetal alcohol spectrum disorder (FASD) is a significant public health concern, yet there is no internationally agreed set of diagnostic criteria or summary of underlying evidence to inform diagnostic decision-making. ...
BACKGROUND: Fetal alcohol spectrum disorder (FASD) is a significant public health concern, yet there is no internationally agreed set …
Effects of the COVID-19 pandemic on maternal-fetal outcomes in a nonepidemic designated hospital: a retrospective study and clinical experience summary.
Gao J, Xiao Z, Li C, Yao Y, Chen L, Xu J, Cheng W. Gao J, et al. BMC Infect Dis. 2024 Oct 15;24(1):1165. doi: 10.1186/s12879-024-09728-9. BMC Infect Dis. 2024. PMID: 39407166 Free PMC article.
OBJECTIVE: To assess the changes in maternal-fetal outcomes in a nonepidemic designated hospital during the COVID-19 pandemic. METHODS: This retrospective cohort study was conducted between January 1, 2019, and December 31, 2021 on pregnant patients. ...
OBJECTIVE: To assess the changes in maternal-fetal outcomes in a nonepidemic designated hospital during the COVID-19 pandemic. METHOD …
Cardiovascular health of women 10 to 20 years after placenta-related pregnancy diseases considering the possible effect of pentaerythrityl tetranitrate treatment during pregnancy on long-term maternal cardiovascular health (PAVA study).
Lößner C, Multhaup A, Bäz L, Lehmann T, Heimann Y, Schleußner E, Franz M, Groten T. Lößner C, et al. PLoS One. 2024 Oct 15;19(10):e0309177. doi: 10.1371/journal.pone.0309177. eCollection 2024. PLoS One. 2024. PMID: 39405308 Free PMC article.
BACKGROUND: Women developing preeclampsia (PE) or fetal growth restriction (FGR) during pregnancy are at higher risk for cardiovascular diseases (CVD) later in life. ...
BACKGROUND: Women developing preeclampsia (PE) or fetal growth restriction (FGR) during pregnancy are at higher risk for cardiovascul …
Fetal meconium peritonitis after maternal hepatitis B: a case report and review of the literature.
Zhang L, Gao B. Zhang L, et al. J Int Med Res. 2024 Oct;52(10):3000605241283633. doi: 10.1177/03000605241283633. J Int Med Res. 2024. PMID: 39403803 Free PMC article. Review.
At 21(+5) weeks, fetal ascites, echogenic bowel, and intra-abdominal calcifications were observed by abdominal ultrasound. ...Close surveillance may allow an early diagnosis of FMP and prevent fetal mortality....
At 21(+5) weeks, fetal ascites, echogenic bowel, and intra-abdominal calcifications were observed by abdominal ultrasound. ...Close s …
Zinc and chitosan-enhanced beta-tricalcium phosphate from calcined fetal bovine bone for mandible reconstruction.
Zhou J, Ma R, Shi W, Lei S, Zhang X, Jiang N, Lin Y, Li Z, Nie M. Zhou J, et al. Front Bioeng Biotechnol. 2024 Sep 27;12:1355493. doi: 10.3389/fbioe.2024.1355493. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 39403673 Free PMC article.
METHODS: In this study, we developed a novel beta-TCP-based scaffold, CFBB, by calcining fetal bovine cancellous bone. To enhance its properties, we modified CFBB with Chitosan (CS) and Zinc (Zn), creating three additional scaffold materials: CFBB/CS, CFBB/Zn(2+), and CFBB …
METHODS: In this study, we developed a novel beta-TCP-based scaffold, CFBB, by calcining fetal bovine cancellous bone. To enhance its …
Regulation of glucose metabolism: Effects on oocyte, preimplantation embryo, assisted reproductive technology and embryonic stem cell.
Xiong YY, Zhu HY, Shi RJ, Wu YF, Fan Y, Jin L. Xiong YY, et al. Heliyon. 2024 Sep 28;10(19):e38551. doi: 10.1016/j.heliyon.2024.e38551. eCollection 2024 Oct 15. Heliyon. 2024. PMID: 39403464 Free PMC article. Review.
Moreover, the interrelationships among glucose metabolism, female reproduction-related diseases and assisted reproductive technologies are focused. In addition, we review a number of analytical methodologies with the intention to integrate a multi-tiered strategy that enco …
Moreover, the interrelationships among glucose metabolism, female reproduction-related diseases and assisted reproductive technologie …
Optimization of culture conditions for HBV-specific T cell expansion in vitro from chronically infected patients.
Wang L, Chen H, Yang Y, Huang Y, Chen W, Mu D. Wang L, et al. BMC Biotechnol. 2024 Oct 14;24(1):80. doi: 10.1186/s12896-024-00908-8. BMC Biotechnol. 2024. PMID: 39402512 Free PMC article.
Concerning amplification efficiency, 4 10(5) cells stimulation was superior to 2 10(6) cells stimulation, AIM-V medium outperformed 1640 medium, and fetal bovine serum (FBS) exceeded human AB serum under comparable conditions. As expected, this procedure is also suitable f …
Concerning amplification efficiency, 4 10(5) cells stimulation was superior to 2 10(6) cells stimulation, AIM-V medium outperformed 1640 med …
Haplotypes analysis reveals the genetic basis of type I CD36 deficiency.
Xia W, Chen D, Li X, Liu J, Xu X, Ye X, Deng J, Ding H, Ren H, Chen Y, Liang H, Lai X, Fu Y. Xia W, et al. Sci Rep. 2024 Oct 14;14(1):23977. doi: 10.1038/s41598-024-74917-0. Sci Rep. 2024. PMID: 39402159 Free PMC article.
We analyzed the CD36 gene sequences in platelet donors and patients with PTR (platelet transfusion refractoriness) and FNAIT (fetal and neonatal alloimmune thrombocytopenia), conducting a detailed haplotype analysis associated with type I CD36 deficiency and FNAIT....
We analyzed the CD36 gene sequences in platelet donors and patients with PTR (platelet transfusion refractoriness) and FNAIT (fetal a …
Comparison of fetal growth patterns from Western India with Intergrowth-21st.
Kinare A, Joshi P, Dangat K, Gupte S, Tipnis M, Singh G, Randhir K, Madiwale S, Pisal H, Wagh G, Lalwani S, Joshi S, Fall C, Sachdev HS. Kinare A, et al. PLoS One. 2024 Oct 14;19(10):e0310710. doi: 10.1371/journal.pone.0310710. eCollection 2024. PLoS One. 2024. PMID: 39401220 Free PMC article.
OBJECTIVE: To generate longitudinal fetal growth data in an Indian population and compare it with Intergrowth-21st. MATERIAL AND METHODS: Fetal biometry data was collected in a prospective longitudinal observational study (REVAMP: Research Exploring Various Aspects …
OBJECTIVE: To generate longitudinal fetal growth data in an Indian population and compare it with Intergrowth-21st. MATERIAL AND METH …
Causal effects of specific gut microbiota on spinal stenosis diseases: a two-sample mendelian randomization study.
Luo K, Zeng W, Li Q, Zhang Y, Liu S, Liu X, Liu S. Luo K, et al. Front Genet. 2024 Sep 26;15:1400847. doi: 10.3389/fgene.2024.1400847. eCollection 2024. Front Genet. 2024. PMID: 39399222 Free PMC article.
BACKGROUND: Although recent observational studies and clinical trials have indicated a strong association between the gut microbiota and spinal stenosis diseases, the causal relationship between them remains unclear. METHODS: Based on large-scale genome-wide association st …
BACKGROUND: Although recent observational studies and clinical trials have indicated a strong association between the gut microbiota and spi …
Critical Threshold of Average Weekly Weight Gain in Overweight Pregnant Women During the Second and Third Trimesters: A Strategy to Prevent Macrosomia.
Wang Y, Wang Z, Sun Y, Yang L, Ma L, Li J, Zhang S, Yang X. Wang Y, et al. Diabetes Metab Syndr Obes. 2024 Oct 9;17:3683-3695. doi: 10.2147/DMSO.S470863. eCollection 2024. Diabetes Metab Syndr Obes. 2024. PMID: 39398387 Free PMC article.
The results of this study highlight the importance of weight management in women in the second and third trimesters, especially those who are overweight, and reasonable control of weight gain will contribute to maternal and fetal health....
The results of this study highlight the importance of weight management in women in the second and third trimesters, especially those who ar …
Term Breech Presentation and Timing of Delivery.
Leybovitz-Haleluya N, Saban A, Yariv A, Hershkovitz R. Leybovitz-Haleluya N, et al. Isr Med Assoc J. 2024 Oct;26(9):555-559. Isr Med Assoc J. 2024. PMID: 39397500 Free article.
OBJECTIVES: To study the influence of gestational age at the time of CD in breech presentation on maternal and fetal complications. METHODS: We conducted a retrospective study including term singleton CDs of breech presentation between February 2020 and January 2022 at a t …
OBJECTIVES: To study the influence of gestational age at the time of CD in breech presentation on maternal and fetal complications. M …
Cardiovascular Diseases During Pregnancy.
Taçoy G, Karçaaltıncaba D, Türkoğlu S. Taçoy G, et al. Turk Kardiyol Dern Ars. 2024 Oct;52(7):536-540. doi: 10.5543/tkda.2024.06228. Turk Kardiyol Dern Ars. 2024. PMID: 39397412 Free article. English.
Pregnancy-associated hemodynamic changes may cause severe complications in patients with cardiovascular diseases. It may also reveal previously undiagnosed conditions or worsen existing ones. To prevent maternal and fetal complications during pregnancy, a thorough e …
Pregnancy-associated hemodynamic changes may cause severe complications in patients with cardiovascular diseases. It may also reveal …
A national study on maternal vomiting during pregnancy in Iran: prevalence, determinants, adverse birth outcomes, and the trend.
Afrashte S, Hajipour M, Darbandi M, Dianatinasab M, Rezaeian S. Afrashte S, et al. BMC Pregnancy Childbirth. 2024 Oct 12;24(1):667. doi: 10.1186/s12884-024-06880-7. BMC Pregnancy Childbirth. 2024. PMID: 39395974 Free PMC article.
This complication is associated with many adverse health outcomes during pregnancy and negatively affect maternal and fetal health. Given the importance of pregnancy period, nutrition education and increase the awareness of pregnant women towards NVP, especially pre-pregna …
This complication is associated with many adverse health outcomes during pregnancy and negatively affect maternal and fetal health. G …
Disappearance of Antiphospholipid Antibodies after anti-CD19 CAR T-Cell Therapy of B-Cell Lymphoma in a Patient with Systemic Lupus Erythematosus and Antiphospholipid Syndrome.
Friedberg E, Wohlfarth P, Schiefer AI, Skrabs C, Pickl WF, Worel N, Staber P, Jäger U, Ay C. Friedberg E, et al. J Thromb Haemost. 2024 Oct 9:S1538-7836(24)00572-5. doi: 10.1016/j.jtha.2024.09.024. Online ahead of print. J Thromb Haemost. 2024. PMID: 39393780 Free article.
Antiphospholipid syndrome is an autoimmune disorder characterized by the development of spontaneous venous, arterial, or microvascular thrombosis and/or pregnancy-related complications (e.g. miscarriages, fetal loss) in the presence of persistent antiphospholipid antibodie …
Antiphospholipid syndrome is an autoimmune disorder characterized by the development of spontaneous venous, arterial, or microvascular throm …
Calcium and Phosphate Metabolism and Related Disorders During Pregnancy and Lactation.
Kovacs CS. Kovacs CS. 2024 Oct 12. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2024 Oct 12. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905396 Free Books & Documents. Review.
Specific adaptations are invoked within each time period to meet the fetal, neonatal, and maternal calcium requirements. During pregnancy, intestinal calcium and phosphate absorption more than double, and this appears to be the main adaptation to meet the fetal dema …
Specific adaptations are invoked within each time period to meet the fetal, neonatal, and maternal calcium requirements. During pregn …
Third-Trimester Cardiovascular Function and Risk of Hypertensive Disorders of Pregnancy.
Lihme F, Basit S, Persson LG, Larsen MO, Lauridsen KH, Lykke JA, Andersen AS, Thorsen-Meyer A, Pihl K, Melbye M, Wohlfahrt J, Boyd HA. Lihme F, et al. J Am Heart Assoc. 2024 Oct 15;13(20):e032673. doi: 10.1161/JAHA.123.032673. Epub 2024 Oct 11. J Am Heart Assoc. 2024. PMID: 39392169 Free article.
BACKGROUND: Whether cardiovascular dysfunction is associated with preeclampsia in women without fetal growth restriction (FGR) is unclear. Our objective was to investigate associations between third-trimester cardiac output (CO) and systemic vascular resistance and risk of …
BACKGROUND: Whether cardiovascular dysfunction is associated with preeclampsia in women without fetal growth restriction (FGR) is unc …
Effect of Music Therapy on Anxiety in Pregnancy: A Systematic Review of Randomized Controlled Trials.
Shafqat N, Agrawal A, Pushpalatha K, Singh B, Verma R, Podder L, Das S, Sutar RF. Shafqat N, et al. Cureus. 2024 Sep 10;16(9):e69066. doi: 10.7759/cureus.69066. eCollection 2024 Sep. Cureus. 2024. PMID: 39391386 Free PMC article. Review.
Pregnancy can heighten anxiety levels, impacting both maternal and fetal well-being. This systematic review synthesizes evidence from 33 randomized controlled trials exploring the effects of music therapy on anxiety in pregnant women. ...The findings consistently de …
Pregnancy can heighten anxiety levels, impacting both maternal and fetal well-being. This systematic review synthesizes evidence from …
Bovine aortic arch: a potential indicator that may not serve in prenatal diagnosis - a study based on fetal anatomy, genetics, and postnatal clinical outcomes.
Liu Y, Gao C, Zhou Y, Zhao S, Shuai X, Zhao E, Chen F, Zhang C. Liu Y, et al. BMC Pregnancy Childbirth. 2024 Oct 10;24(1):658. doi: 10.1186/s12884-024-06852-x. BMC Pregnancy Childbirth. 2024. PMID: 39390395 Free PMC article.
METHODS: A retrospective analysis was conducted on 216 fetuses diagnosed with bovine aortic arch through prenatal ultrasound screening at the First Affiliated Hospital of Anhui Medical University and the No.901 Hospital of the Joint Service of the People's Liberation Army from Ja …
METHODS: A retrospective analysis was conducted on 216 fetuses diagnosed with bovine aortic arch through prenatal ultrasound screening at th …
Transplacental SARS-CoV-2 protein ORF8 binds to complement C1q to trigger fetal inflammation.
Azamor T, Familiar-Macedo D, Salem GM, Onwubueke C, Melano I, Bian L, Vasconcelos Z, Nielsen-Saines K, Wu X, Jung JU, Lin F, Goje O, Chien E, Gordon S, Foster CB, Aly H, Farrell RM, Chen W, Foo SS. Azamor T, et al. EMBO J. 2024 Oct 10. doi: 10.1038/s44318-024-00260-9. Online ahead of print. EMBO J. 2024. PMID: 39390219 Free article.
While ~26% of fetal tissues were positive for SARS-CoV-2 RNA, more than 60% of fetal tissues contained SARS-CoV-2 ORF8 proteins, suggesting transplacental transfer of this viral accessory protein. ...In conclusion, an ORF8-C1q-dependent complement activation pathway …
While ~26% of fetal tissues were positive for SARS-CoV-2 RNA, more than 60% of fetal tissues contained SARS-CoV-2 ORF8 protein …
Utilizing non-invasive prenatal test sequencing data for human genetic investigation.
Liu S, Liu Y, Gu Y, Lin X, Zhu H, Liu H, Xu Z, Cheng S, Lan X, Li L, Huang M, Li H, Nielsen R, Davies RW, Albrechtsen A, Chen GB, Qiu X, Jin X, Huang S. Liu S, et al. Cell Genom. 2024 Oct 9;4(10):100669. doi: 10.1016/j.xgen.2024.100669. Cell Genom. 2024. PMID: 39389018 Free article.
Non-invasive prenatal testing (NIPT) employs ultra-low-pass sequencing of maternal plasma cell-free DNA to detect fetal trisomy. Its global adoption has established NIPT as a large human genetic resource for exploring genetic variations and their associations with phenotyp …
Non-invasive prenatal testing (NIPT) employs ultra-low-pass sequencing of maternal plasma cell-free DNA to detect fetal trisomy. Its …
Genetic analyses of 104 phenotypes in 20,900 Chinese pregnant women reveal pregnancy-specific discoveries.
Xiao H, Li L, Yang M, Zhang X, Zhou J, Zeng J, Zhou Y, Lan X, Liu J, Lin Y, Zhong Y, Zhang X, Wang L, Cao Z, Liu P, Mei H, Cai M, Cai X, Tao Y, Zhu Y, Yu C, Hu L, Wang Y, Huang Y, Su F, Gao Y, Zhou R, Xu X, Yang H, Wang J, Zhu H, Zhou A, Jin X. Xiao H, et al. Cell Genom. 2024 Oct 9;4(10):100633. doi: 10.1016/j.xgen.2024.100633. Cell Genom. 2024. PMID: 39389017 Free article.
Monitoring biochemical phenotypes during pregnancy is vital for maternal and fetal health, allowing early detection and management of pregnancy-related conditions to ensure safety for both. ...The partitioning heritability underscored the significant roles of fetal
Monitoring biochemical phenotypes during pregnancy is vital for maternal and fetal health, allowing early detection and management of …
Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese maternities.
Zhu H, Xiao H, Li L, Yang M, Lin Y, Zhou J, Zhang X, Zhou Y, Lan X, Liu J, Zeng J, Wang L, Zhong Y, Qian X, Cao Z, Liu P, Mei H, Cai M, Cai X, Tang Z, Hu L, Zhou R, Xu X, Yang H, Wang J, Jin X, Zhou A. Zhu H, et al. Cell Genom. 2024 Oct 9;4(10):100631. doi: 10.1016/j.xgen.2024.100631. Cell Genom. 2024. PMID: 39389014 Free article.
Glycemic traits are critical indicators of maternal and fetal health during pregnancy. We performed genetic analysis for five glycemic traits in 14,744 Chinese pregnant women. ...
Glycemic traits are critical indicators of maternal and fetal health during pregnancy. We performed genetic analysis for five glycemi …
Highly efficient generation of self-renewing trophoblast from human pluripotent stem cells.
Slamecka J, Ryu S, Tristan CA, Chu PH, Weber C, Deng T, Gedik Y, Ormanoglu P, Voss TC, Simeonov A, Singeç I. Slamecka J, et al. iScience. 2024 Sep 3;27(10):110874. doi: 10.1016/j.isci.2024.110874. eCollection 2024 Oct 18. iScience. 2024. PMID: 39386760 Free PMC article.
However, lineage specification into trophectoderm (TE) and trophoblast (TB) differentiation remains poorly understood, and access to well-characterized placental cells for biomedical research is limited, largely depending on fetal tissues or cancer cell lines. Here, we dev …
However, lineage specification into trophectoderm (TE) and trophoblast (TB) differentiation remains poorly understood, and access to well-ch …
Impact of genomic background and developmental state on signaling pathways and response to therapy in glioblastoma patient-derived cells.
Berezovsky A, Nuga O, Datta I, Bergman K, Sabedot T, Gurdziel K, Irtenkauf S, Hasselbach L, Meng Y, Mueller C, Petricoin EF, Brown S, Purandare N, Aras S, Mikkelsen T, Poisson L, Noushmehr H, Ruden D, deCarvalho AC. Berezovsky A, et al. bioRxiv [Preprint]. 2024 Sep 23:2024.03.14.585115. doi: 10.1101/2024.03.14.585115. bioRxiv. 2024. PMID: 39386580 Free PMC article. Preprint.
In this study, we employed targeted proteomics to assess the response of a genomically-diverse panel of GBM patient-derived cancer stem cells (CSCs) to astrocytic differentiation, growth factor withdrawal and traditional high fetal bovine serum culture. Our findings reveal …
In this study, we employed targeted proteomics to assess the response of a genomically-diverse panel of GBM patient-derived cancer stem cell …
SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids.
Kumar D, Karvas RM, Jones BR, McColl ER, Diveley E, Sukanta J, Surendra S, Kelly JC, Theunissen TW, Mysorekar IU. Kumar D, et al. bioRxiv [Preprint]. 2024 Sep 25:2024.09.25.614931. doi: 10.1101/2024.09.25.614931. bioRxiv. 2024. PMID: 39386577 Free PMC article. Preprint.
We and others have previously shown that SARS-CoV-2 can colonize maternal and fetal placental cells, yet the specific mechanisms remain unclear. In this study, we investigate ORF3a, a key accessory protein of SARS-CoV-2 that exhibits continuous mutations. ...
We and others have previously shown that SARS-CoV-2 can colonize maternal and fetal placental cells, yet the specific mechanisms rema …
The Human Neural Cell Atlas of Zika Infection in developing human brain tissue: viral pathogenesis, innate immunity, and lineage reprogramming.
Stokes C, Whitmore LS, Moreno D, Malhotra K, Tisoncik-Go J, Tran E, Wren N, Glass I; Birth Defects Research Laboratory (BDRL); Young JE, Gale M Jr. Stokes C, et al. bioRxiv [Preprint]. 2024 Sep 29:2024.09.27.615512. doi: 10.1101/2024.09.27.615512. bioRxiv. 2024. PMID: 39386476 Free PMC article. Preprint.
Zika virus (ZIKV) infection during pregnancy can lead to fetal brain infection and developmental anomalies collectively known as congenital Zika syndrome (CZS). To define the molecular features underlying CZS in a relevant human cell model, we evaluated ZIKV infection and …
Zika virus (ZIKV) infection during pregnancy can lead to fetal brain infection and developmental anomalies collectively known as cong …
The effect of intrauterine growth restriction on the developing pancreatic immune system.
Golden TN, Garifallou JP, Conine CC, Simmons RA. Golden TN, et al. bioRxiv [Preprint]. 2024 Sep 23:2024.09.19.613902. doi: 10.1101/2024.09.19.613902. bioRxiv. 2024. PMID: 39386426 Free PMC article. Preprint.
Immune cells also play a role in pathology and are implicated in diseases such as diabetes induced by intrauterine growth restriction (IUGR). We hypothesized that the resident immune system is established during neonatal development and disrupted by IUGR. ...
Immune cells also play a role in pathology and are implicated in diseases such as diabetes induced by intrauterine growth restriction …
Treatments for cesarean scar pregnancy: a systematic review and meta-analysis.
Alameddine S, Lucidi A, Jurkovic D, Timor Tritsch I, Coutinho CM, Ranucci L, Buca D, Khalil A, Jauniaux E, Mappa I, D'Antonio F. Alameddine S, et al. J Matern Fetal Neonatal Med. 2024 Dec;37(1):2327569. doi: 10.1080/14767058.2024.2327569. Epub 2024 Oct 9. J Matern Fetal Neonatal Med. 2024. PMID: 39385517 Free article. Review.
Genetic modifications of EGLN1 reactivate HbF production in β0-thalassemia/HbE.
Jan-Ngam V, Boontha S, Tubsuwan A, Wongpalee SP, Fanhchaksai K, Tantiworawit A, Charoenkwan P, Khamphikham P. Jan-Ngam V, et al. Heliyon. 2024 Sep 18;10(18):e38020. doi: 10.1016/j.heliyon.2024.e38020. eCollection 2024 Sep 30. Heliyon. 2024. PMID: 39381253 Free PMC article.
Reactivation of fetal hemoglobin (HbF, alpha(2)gamma(2)) potentially alleviates clinical presentation in beta-thalassemia. ...Our findings introduce an additional mechanism for HbF regulation in beta-thalassemia and propose that targeting the canonical oxygen-sensing pathw …
Reactivation of fetal hemoglobin (HbF, alpha(2)gamma(2)) potentially alleviates clinical presentation in beta-thalassemia. ...Our fin …
Syphilis and pregnancy.
Duarte G, Melli PPDS, Miranda AE, Milanez HMBPM, Menezes ML, Travassos AG, Kreitchmann R. Duarte G, et al. Rev Bras Ginecol Obstet. 2024 Sep 23;46:e-FPS09. doi: 10.61622/rbgo/2024FPS09. eCollection 2024. Rev Bras Ginecol Obstet. 2024. PMID: 39380581 Free PMC article.
Although transforming the recording of syphilis and congenital syphilis into notifiable diseases improved the records and has made it possible to measure the occurrence of these diseases and create solutions, no effects on reducing their frequency have been reached …
Although transforming the recording of syphilis and congenital syphilis into notifiable diseases improved the records and has made it …
Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects.
Jiang X, Lian X, Wei K, Zhang J, Yu K, Li H, Ma H, Cai Y, Pang L. Jiang X, et al. Stem Cell Res Ther. 2024 Oct 8;15(1):354. doi: 10.1186/s13287-024-03961-4. Stem Cell Res Ther. 2024. PMID: 39380099 Free PMC article. Review.
Acute coronary syndromes, such as myocardial infarction (MI), lack effective therapies beyond heart transplantation, which is often hindered by donor scarcity and postoperative complications. ...However, hiPSC-derived cardiomyocytes (hiPSC-cardiomyocytes) exhibit fetal
Acute coronary syndromes, such as myocardial infarction (MI), lack effective therapies beyond heart transplantation, which is often h …
International expert consensus statement on physiological interpretation of cardiotocograph (CTG): First revision (2024).
Chandraharan E, Pereira S, Ghi T, Gracia Perez-Bonfils A, Fieni S, Jia YJ, Griffiths K, Sukumaran S, Ingram C, Reeves K, Bolten M, Loser K, Carreras E, Suy A, Garcia-Ruiz I, Galli L, Zaima A. Chandraharan E, et al. Eur J Obstet Gynecol Reprod Biol. 2024 Nov;302:346-355. doi: 10.1016/j.ejogrb.2024.09.034. Epub 2024 Oct 2. Eur J Obstet Gynecol Reprod Biol. 2024. PMID: 39378709 Free article.
This guideline ensured a paradigm shift from classifying CTG by arbitrarily grouping certain features of the fetal heart rate into different "categories", and then, randomly combining them to arrive at an overall classification of CTG traces into "Normal, Suspicious and Pa …
This guideline ensured a paradigm shift from classifying CTG by arbitrarily grouping certain features of the fetal heart rate into di …
A new ex vivo model system to analyze factors affecting the integrity of fetal membranes in fetoscopic surgery.
Robmann S, Hopf R, Giampietro C, Moser L, Dolder A, Sanz Cortes M, Ehrbar M, Ochsenbein N, Deprest J, Mazza E. Robmann S, et al. J Mech Behav Biomed Mater. 2024 Oct 1;160:106764. doi: 10.1016/j.jmbbm.2024.106764. Online ahead of print. J Mech Behav Biomed Mater. 2024. PMID: 39378672 Free article.
Change in fetal membranes stiffness is quantified during the phase mimicking surgery through measurement of membranes' strain in response to cyclic overpressure. ...This new model is a versatile platform for analyzing the mechanical, histological, and biological implicatio …
Change in fetal membranes stiffness is quantified during the phase mimicking surgery through measurement of membranes' strain in resp …
Substance Use During Pregnancy.
Desiron M, Saad C, Tecco JM, Kadji C. Desiron M, et al. Psychiatr Danub. 2024 Sep;36(Suppl 2):241-249. Psychiatr Danub. 2024. PMID: 39378478 Free article. Review.
These symptoms can, however, be intense and constitute real psychiatric syndromes, particularly when the woman presents vulnerability factors. While fetal exposure to alcohol and other drugs is one of the leading preventable causes of developmental delay and birth defects …
These symptoms can, however, be intense and constitute real psychiatric syndromes, particularly when the woman presents vulnerability factor …
A case series of chorioangiomas in placentas with clinical indication for histological examination.
Nardi E, Silvano A, Castiglione F, Olivo E, Abati I, Massi D, Seravalli V, Di Tommaso M. Nardi E, et al. Pathologica. 2024 Aug;116(4):258-266. doi: 10.32074/1591-951X-1003. Pathologica. 2024. PMID: 39377509 Free PMC article.
Large chorioangiomas, measuring more than 4-5 cm in diameter, can usually be detected prenatally by gray-scale or color Doppler sonography, and may be associated with maternal or fetal complications, such as preeclampsia, maternal mirror syndrome, preterm delivery, nonimmu …
Large chorioangiomas, measuring more than 4-5 cm in diameter, can usually be detected prenatally by gray-scale or color Doppler sonography, …
Maternal diet during pregnancy and adaptive changes in the maternal and fetal pancreas have implications for future metabolic health.
Hill DJ, Hill TG. Hill DJ, et al. Front Endocrinol (Lausanne). 2024 Sep 23;15:1456629. doi: 10.3389/fendo.2024.1456629. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39377073 Free PMC article. Review.
Fetal and neonatal development is a critical period for the establishment of the future metabolic health and disease risk of an individual. Both maternal undernutrition and overnutrition can result in abnormal fetal organ development resulting in inappropriate birth
Fetal and neonatal development is a critical period for the establishment of the future metabolic health and disease risk of an indiv
Delta neutrophil index (DNI) as a potential biomarker for fetal growth restriction: insights from maternal hematological changes and neonatal outcomes.
Tonyali NV, Sarsmaz K, Bayraktar B, Kahraman NC, Sucu ST, Aktemur G, Cakir BT, Seyhanli Z, Karabay G, Cakir A, Ustun Y. Tonyali NV, et al. BMC Pregnancy Childbirth. 2024 Oct 7;24(1):655. doi: 10.1186/s12884-024-06853-w. BMC Pregnancy Childbirth. 2024. PMID: 39375632 Free PMC article.
BACKGROUND: This study investigates the role of Delta Neutrophil Index (DNI), an inflammation marker, in late-onset fetal growth restriction (LO-FGR) and its prediction of composite adverse neonatal outcomes. METHODS: A retrospective study was conducted on 684 pregnant wom …
BACKGROUND: This study investigates the role of Delta Neutrophil Index (DNI), an inflammation marker, in late-onset fetal growth rest …
Upper Esophageal Fetal Rhabdomyoma: A Case Series of 4 Children and Review of Literature.
Liu Z, Meng Y, Li Y, Zhang X, Liu Q, Sun N, Ji T, Li X, Liu Y, Wang S, Ni X. Liu Z, et al. Ear Nose Throat J. 2024 Oct 7:1455613241286495. doi: 10.1177/01455613241286495. Online ahead of print. Ear Nose Throat J. 2024. PMID: 39374098 Free article. Review.
Objective: The aims of the present study were to provide objective evidence for identifying fetal rhabdomyoma (RM) in the upper esophagus of children, enhance clinical understanding of the diagnosis and treatment of this condition, and optimize the treatment strategy for …
Objective: The aims of the present study were to provide objective evidence for identifying fetal rhabdomyoma (RM) in the upper esoph …
Rescue Cervical Cerclage for Previable Birth Prevention: A Comprehensive Review of Indications, Techniques, and Outcomes.
Ughade PA, Shrivastava D, Chaudhari K. Ughade PA, et al. Cureus. 2024 Sep 4;16(9):e68619. doi: 10.7759/cureus.68619. eCollection 2024 Sep. Cureus. 2024. PMID: 39371694 Free PMC article. Review.
Key aspects evaluated include the criteria for intervention, various surgical techniques employed, and the associated maternal and fetal outcomes. Comparative analysis was also performed with other preventive measures, such as progesterone therapy and bed rest. ...
Key aspects evaluated include the criteria for intervention, various surgical techniques employed, and the associated maternal and fetal
Mechanism of collagen type IV regulation by focal adhesion kinase during retained fetal membranes in dairy cows.
Luo C, Chang J, Yao W, Qian W, Bai Y, Fu S, Xia C. Luo C, et al. Sci Rep. 2024 Oct 6;14(1):23250. doi: 10.1038/s41598-024-74947-8. Sci Rep. 2024. PMID: 39370419 Free PMC article.
Retained fetal membranes (RFM) is an important reproductive disease in dairy cows, caused by maternal and fetal placental tissue adhesion. The main collagen in maternal and fetal placenta tissues is collagen type IV (COL-IV) and its breakdown is the key to pl …
Retained fetal membranes (RFM) is an important reproductive disease in dairy cows, caused by maternal and fetal placental tiss …
Epidemiological and Clinical Characteristics of Women Living with HIV in Korea.
Ahn SM, Lee YS, Han M, Lee JA, Seong JE, Baek YJ, Hyun J, Kim JH, Ahn JY, Oh DH, Jeong SJ, Baek JH, Ku NS, Choi HK, Park Y, Chin B, Kim YK, Yeom JS, Choi YH, Choi JY. Ahn SM, et al. Infect Chemother. 2024 Sep;56(3):369-377. doi: 10.3947/ic.2024.0057. Infect Chemother. 2024. PMID: 39370122 Free PMC article.
Among the participants, 334 (77.7%) were Korean, 27 (6.1%) were Southeast Asian, and 19 (4.3%) were African. Antiretroviral therapy was initiated by 404 WLWH (91.2%). We observed 118 pregnancies in WLWH following their HIV diagnosis, resulting in 78 live births (66.1%), 18 …
Among the participants, 334 (77.7%) were Korean, 27 (6.1%) were Southeast Asian, and 19 (4.3%) were African. Antiretroviral therapy w …
The role of glypican-3 in hepatocellular carcinoma: Insights into diagnosis and therapeutic potential.
Devan AR, Nair B, Pradeep GK, Alexander R, Vinod BS, Nath LR, Calina D, Sharifi-Rad J. Devan AR, et al. Eur J Med Res. 2024 Oct 5;29(1):490. doi: 10.1186/s40001-024-02073-2. Eur J Med Res. 2024. PMID: 39369212 Free PMC article. Review.
Glypican-3 (GPC-3) is predominantly found in the placenta and fetal liver, with limited expression in adult tissues. Its re-expression in hepatocellular carcinoma (HCC) and secretion into the serum highlights its potential as a diagnostic marker. ...Ongoing investigations, …
Glypican-3 (GPC-3) is predominantly found in the placenta and fetal liver, with limited expression in adult tissues. Its re-expressio …
Evaluating T1-weighted MRI techniques for fetal gastrointestinal diagnostics: A comparative study.
Zeng Y, Zhang R, Wang Q, He J, Yu D, Tao G, Xin J, Xue L, Zhao M. Zeng Y, et al. Magn Reson Imaging. 2024 Dec;114:110242. doi: 10.1016/j.mri.2024.110242. Epub 2024 Oct 3. Magn Reson Imaging. 2024. PMID: 39368522 Free article.
PURPOSE: In clinical practice, fetal gastrointestinal magnetic resonance imaging (MRI) encounters significant challenges. ...Among these participants, 22 were suspected of having fetal gastrointestinal anomalies based on ultrasound findings, while the remaining 45 w …
PURPOSE: In clinical practice, fetal gastrointestinal magnetic resonance imaging (MRI) encounters significant challenges. ...Among th …
Impact of SARS-CoV-2 infection and vaccination on cesarean section outcomes: a retrospective analysis.
Yeniocak AS, Tercan C, Dagdeviren E, Arabaci O, Arabaci EEG. Yeniocak AS, et al. Ann Saudi Med. 2024 Sep-Oct;44(5):306-318. doi: 10.5144/0256-4947.2024.306. Epub 2024 Oct 3. Ann Saudi Med. 2024. PMID: 39368119 Free PMC article.
BACKGROUND: Pregnant individuals have faced unique challenges during the COVID-19 pandemic, necessitating a closer examination of maternal and fetal health outcomes. OBJECTIVES: Investigate the morbidity and mortality associated with SARS-CoV-2 infection among pregnant ind …
BACKGROUND: Pregnant individuals have faced unique challenges during the COVID-19 pandemic, necessitating a closer examination of maternal a …
Pregnant woman with severe subaortic stenosis successfully treated with open-heart surgery resection: A case report.
Fernandes AL, Pomerantzeff PMA, Dinato FJ, Pardi MM, Jatene FB. Fernandes AL, et al. Int J Surg Case Rep. 2024 Nov;124:110395. doi: 10.1016/j.ijscr.2024.110395. Epub 2024 Sep 30. Int J Surg Case Rep. 2024. PMID: 39366114 Free PMC article.
PRESENTATION OF CASE: A 34-year-old primigravida at gestational week 19, was admitted to the emergency department with a highly symptomatic severe SubAS refractory to medical treatment. Obstetric evaluation showed normal fetal development. The patient was treated with hear …
PRESENTATION OF CASE: A 34-year-old primigravida at gestational week 19, was admitted to the emergency department with a highly symptomatic …
Schistosoma japonicum infection-mediated downregulation of lncRNA Malat1 contributes to schistosomiasis hepatic fibrosis by the Malat1/miR-96/Smad7 pathway.
Jiang P, Ye S, Fan X, Tian Y, Zhang D, Pan W. Jiang P, et al. Parasit Vectors. 2024 Oct 3;17(1):413. doi: 10.1186/s13071-024-06499-9. Parasit Vectors. 2024. PMID: 39363237 Free PMC article.
Primary HSCs were isolated from infected mice using collagenase digestion and density-gradient centrifugation, cultured in DMEM with 10% fetal bovine serum. Dual-luciferase reporter assays, nuclear cytoplasm fractionation and RIP assays were employed to assess the relation …
Primary HSCs were isolated from infected mice using collagenase digestion and density-gradient centrifugation, cultured in DMEM with 10% …
An integrative single-cell atlas for exploring the cellular and temporal specificity of genes related to neurological disorders during human brain development.
Kim S, Lee J, Koh IG, Ji J, Kim HJ, Kim E, Park J, Park JE, An JY. Kim S, et al. Exp Mol Med. 2024 Oct;56(10):2271-2282. doi: 10.1038/s12276-024-01328-6. Epub 2024 Oct 3. Exp Mol Med. 2024. PMID: 39363111 Free article.
Furthermore, we explored the regulatory mechanisms involved in early brain development, revealing enriched patterns of fetal cell types associated with neuronal disorders indicative of the prenatal stage's influence on disease determination. ...
Furthermore, we explored the regulatory mechanisms involved in early brain development, revealing enriched patterns of fetal cell typ …
Network modeling links kidney developmental programs and the cancer type-specificity of VHL mutations.
Dong X, Zhang D, Zhang X, Liu Y, Liu Y. Dong X, et al. NPJ Syst Biol Appl. 2024 Oct 3;10(1):114. doi: 10.1038/s41540-024-00445-2. NPJ Syst Biol Appl. 2024. PMID: 39362887 Free PMC article.
Therefore, we designed a computational analysis framework by combining single-cell gene expression profiles during fetal organ development, latent factor discovery, and information theory-based differential network analysis to systematically identify transcription factors …
Therefore, we designed a computational analysis framework by combining single-cell gene expression profiles during fetal organ develo …
"An update on the approach to treatment of Sjogren's Disease in pregnancy".
Cue LV, Rosenn B. Cue LV, et al. J Matern Fetal Neonatal Med. 2024 Dec;37(1):2411583. doi: 10.1080/14767058.2024.2411583. Epub 2024 Oct 3. J Matern Fetal Neonatal Med. 2024. PMID: 39362796 Free article. Review.
Attention to detail and familiarity with the most recent research and guidelines in this field are required to achieve optimal maternal and fetal outcomes. Such complications include pregnancy induced hypertension, fetal growth restriction, thromboembolic events, an …
Attention to detail and familiarity with the most recent research and guidelines in this field are required to achieve optimal maternal and …
Cellular uptake of CPX-351 by scavenger receptor class B type 1-mediated nonendocytic pathway.
Araie H, Hosono N, Yamauchi T. Araie H, et al. Exp Hematol. 2024 Oct 2:104651. doi: 10.1016/j.exphem.2024.104651. Online ahead of print. Exp Hematol. 2024. PMID: 39362576 Free article.
We investigated the uptake pathway into leukemia cells based on PC analysis of CPX-351, a liposome containing cytarabine and daunorubicin in a fixed 5:1 synergistic molar ratio. The PC of CPX-351 mixed with fetal bovine serum was analyzed by nanoflow liquid chromatography- …
We investigated the uptake pathway into leukemia cells based on PC analysis of CPX-351, a liposome containing cytarabine and daunorubicin in …
Beyond the womb: pontine hemorrhage's impact on maternal and fetal outcomes: a case report from Nepal.
Yadav J, Bhusal K, Thapaliya I, Bhandari K, Jha SS, Khadayat R, Ghimire A. Yadav J, et al. Ann Med Surg (Lond). 2024 Aug 7;86(10):6173-6178. doi: 10.1097/MS9.0000000000002455. eCollection 2024 Oct. Ann Med Surg (Lond). 2024. PMID: 39359810 Free PMC article.
Diagnosis requires a multidisciplinary approach with history, clinical examination, and radiological imaging like CT and MRI. Treatment involved antiplatelet therapy, which ensured favorable maternal and fetal outcomes for our patient. CONCLUSION: In summary, this c …
Diagnosis requires a multidisciplinary approach with history, clinical examination, and radiological imaging like CT and MRI. Treatment invo …
Pemphigus and Pregnancy.
De D, Shah S, Mahajan R, Handa S. De D, et al. Indian Dermatol Online J. 2024 May 20;15(5):749-757. doi: 10.4103/idoj.idoj_632_23. eCollection 2024 Sep-Oct. Indian Dermatol Online J. 2024. PMID: 39359288 Free PMC article. Review.
Fetal outcomes like stillbirth and neonatal pemphigus have been reported, the latter being a consequence of a transient transplacental transfer of autoantibodies. Management needs to be individualized keeping the risk/benefit ratios of therapies in mind while optimi
Fetal outcomes like stillbirth and neonatal pemphigus have been reported, the latter being a consequence of a transient transplacenta