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Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers.
Tsafou K, Katschnig AM, Radic-Sarikas B, Mutz CN, Iljin K, Schwentner R, Kauer MO, Mühlbacher K, Aryee DNT, Westergaard D, Haapa-Paananen S, Fey V, Superti-Furga G, Toretsky J, Brunak S, Kovar H. Tsafou K, et al. Among authors: fey v. Oncotarget. 2018 Jul 24;9(57):31018-31031. doi: 10.18632/oncotarget.25760. eCollection 2018 Jul 24. Oncotarget. 2018. PMID: 30123424 Free PMC article.
Wnt signalling is a bi-directional vulnerability of cancer cells.
Duffy DJ, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, Haley B, Whilde J, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W. Duffy DJ, et al. Among authors: fey v. Oncotarget. 2016 Sep 13;7(37):60310-60331. doi: 10.18632/oncotarget.11203. Oncotarget. 2016. PMID: 27531891 Free PMC article.
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.
Duffy DJ, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, Mehta JP, Killick K, Whilde J, Turriziani B, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W. Duffy DJ, et al. Among authors: fey d, fey v. Oncotarget. 2015 Dec 22;6(41):43182-201. doi: 10.18632/oncotarget.6568. Oncotarget. 2015. PMID: 26673823 Free PMC article.
29 results