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Year Number of Results
2013 1
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2015 1
2018 1
2019 3
2020 4
2021 5
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2024 5
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2026 3

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40 results

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Page 1
Succination inactivates gasdermin D and blocks pyroptosis.
Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA. Humphries F, et al. Science. 2020 Sep 25;369(6511):1633-1637. doi: 10.1126/science.abb9818. Epub 2020 Aug 20. Science. 2020. PMID: 32820063 Free PMC article.
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Shmuel-Galia L, et al. Among authors: humphries f. Immunity. 2021 Jun 8;54(6):1137-1153.e8. doi: 10.1016/j.immuni.2021.05.008. Epub 2021 May 28. Immunity. 2021. PMID: 34051146 Free PMC article.
Nitrofuran-Based STING Inhibitors.
Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Mathur A, Rajoria S, Green RM, Allabaji A, Nellikkalaya S, Paul S, Vidadala SR, Kumar Sarkar S, Patil SN, Hale J, Humphries F, Fitzgerald KA, Thompson PR. Barasa L, et al. Among authors: humphries f. ACS Omega. 2025 Sep 4;10(36):41693-41706. doi: 10.1021/acsomega.5c05578. eCollection 2025 Sep 16. ACS Omega. 2025. PMID: 40978405 Free PMC article.
Inflammasomopathies: mechanisms and disease signatures.
Cahill S, Humphries F. Cahill S, et al. Among authors: humphries f. Trends Immunol. 2025 May;46(5):372-385. doi: 10.1016/j.it.2025.03.008. Epub 2025 Apr 21. Trends Immunol. 2025. PMID: 40263090 Review.
Targeting STING oligomerization with small-molecule inhibitors.
Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Humphries F, et al. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2305420120. doi: 10.1073/pnas.2305420120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549268 Free PMC article.
Alternative cGAS signaling promotes herpes simplex encephalitis.
Shmuel-Galia L, Jiang Z, Stine L, Cahill S, Ng SL, Wilson R, Kandasamy RK, Kurt-Jones EA, Ramanjulu JM, Bertin J, Kasparcova V, Pesiridis GS, Fitzgerald KA, Humphries F. Shmuel-Galia L, et al. Among authors: humphries f. Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2423873122. doi: 10.1073/pnas.2423873122. Epub 2025 May 27. Proc Natl Acad Sci U S A. 2025. PMID: 40424128 Free PMC article.
Triazole-based STING inhibitors.
Singh A, Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Rossetti T, Green RM, Humphries F, Thompson PR. Singh A, et al. Among authors: humphries f. Bioorg Med Chem. 2026 Jan 1;132:118484. doi: 10.1016/j.bmc.2025.118484. Epub 2025 Nov 8. Bioorg Med Chem. 2026. PMID: 41242038 Free PMC article.
Interferons in human inborn errors of disease.
Stine L, Cahill S, Humphries F. Stine L, et al. Among authors: humphries f. mBio. 2025 Aug 13;16(8):e0157025. doi: 10.1128/mbio.01570-25. Epub 2025 Jun 24. mBio. 2025. PMID: 40552831 Free PMC article. Review.
40 results