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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 22
1964 54
1965 23
1966 25
1967 40
1968 64
1969 91
1970 93
1971 82
1972 115
1973 124
1974 121
1975 108
1976 130
1977 81
1978 94
1979 105
1980 117
1981 137
1982 158
1983 159
1984 171
1985 202
1986 179
1987 247
1988 342
1989 413
1990 519
1991 531
1992 505
1993 564
1994 600
1995 755
1996 669
1997 717
1998 703
1999 757
2000 881
2001 890
2002 961
2003 1098
2004 1161
2005 1251
2006 1304
2007 1401
2008 1522
2009 1382
2010 1530
2011 1725
2012 1869
2013 1986
2014 2188
2015 2333
2016 2553
2017 2509
2018 2403
2019 2363
2020 2796
2021 2847
2022 2654
2023 2203
2024 29

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49,157 results

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Page 1
Fibrosis: from mechanisms to medicines.
Henderson NC, Rieder F, Wynn TA. Henderson NC, et al. Nature. 2020 Nov;587(7835):555-566. doi: 10.1038/s41586-020-2938-9. Epub 2020 Nov 25. Nature. 2020. PMID: 33239795 Free PMC article. Review.
Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the industrialized world. ...Here we discuss the transformative experimental strategies that are being leveraged to dissect the key cellular and molecular mechanisms that regulate fibrosis …
Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the industrialized world. ...Here we discuss the tran …
Mechanisms of fibrosis: therapeutic translation for fibrotic disease.
Wynn TA, Ramalingam TR. Wynn TA, et al. Nat Med. 2012 Jul 6;18(7):1028-40. doi: 10.1038/nm.2807. Nat Med. 2012. PMID: 22772564 Free PMC article. Review.
Fibrosis is a pathological feature of most chronic inflammatory diseases. Fibrosis, or scarring, is defined by the accumulation of excess extracellular matrix components. ...
Fibrosis is a pathological feature of most chronic inflammatory diseases. Fibrosis, or scarring, is defined by the accumulatio …
Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis.
Meyer KC. Meyer KC. Expert Rev Respir Med. 2017 May;11(5):343-359. doi: 10.1080/17476348.2017.1312346. Epub 2017 Apr 10. Expert Rev Respir Med. 2017. PMID: 28345383 Review.
Expert commentary: Many genetic variants have been identified that are associated with risk of developing pulmonary fibrosis, and an improved understanding of the influence of both genomic and epigenomic factors in the development of pulmonary fibrosis is rapidly ev …
Expert commentary: Many genetic variants have been identified that are associated with risk of developing pulmonary fibrosis, and an …
Pulmonary fibrosis: patterns and perpetrators.
Noble PW, Barkauskas CE, Jiang D. Noble PW, et al. J Clin Invest. 2012 Aug;122(8):2756-62. doi: 10.1172/JCI60323. Epub 2012 Aug 1. J Clin Invest. 2012. PMID: 22850886 Free PMC article. Review.
However, the disease is heterogeneous, and the failure to accurately discern between forms of fibrosing lung diseases leads to inaccurate treatments. Pulmonary fibrosis occurring in the context of connective tissue diseases is often characterized by a distinct patte …
However, the disease is heterogeneous, and the failure to accurately discern between forms of fibrosing lung diseases leads to inaccu …
Targeting renal fibrosis: Mechanisms and drug delivery systems.
Nastase MV, Zeng-Brouwers J, Wygrecka M, Schaefer L. Nastase MV, et al. Adv Drug Deliv Rev. 2018 Apr;129:295-307. doi: 10.1016/j.addr.2017.12.019. Epub 2017 Dec 27. Adv Drug Deliv Rev. 2018. PMID: 29288033 Review.
Renal fibrosis is the common outcome of many chronic kidney diseases (CKD) independent of the underlying etiology. ...In this review, we briefly describe mechanisms of renal fibrosis and methods of drug transfer into the kidney. Various tools used in gene therapy to …
Renal fibrosis is the common outcome of many chronic kidney diseases (CKD) independent of the underlying etiology. ...In this review, …
Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs).
Spagnolo P, Distler O, Ryerson CJ, Tzouvelekis A, Lee JS, Bonella F, Bouros D, Hoffmann-Vold AM, Crestani B, Matteson EL. Spagnolo P, et al. Ann Rheum Dis. 2021 Feb;80(2):143-150. doi: 10.1136/annrheumdis-2020-217230. Epub 2020 Oct 9. Ann Rheum Dis. 2021. PMID: 33037004 Free PMC article. Review.
Patients with clinically distinct ILDs, whether CTD-related or not, can exhibit a pattern of common clinical disease behaviour (declining lung function, worsening respiratory symptoms and higher mortality), attributable to progressive fibrosis in the lungs. In recent years …
Patients with clinically distinct ILDs, whether CTD-related or not, can exhibit a pattern of common clinical disease behaviour (declining lu …
Progressive pulmonary fibrosis: an expert group consensus statement.
Rajan SK, Cottin V, Dhar R, Danoff S, Flaherty KR, Brown KK, Mohan A, Renzoni E, Mohan M, Udwadia Z, Shenoy P, Currow D, Devraj A, Jankharia B, Kulshrestha R, Jones S, Ravaglia C, Quadrelli S, Iyer R, Dhooria S, Kolb M, Wells AU. Rajan SK, et al. Eur Respir J. 2023 Mar 30;61(3):2103187. doi: 10.1183/13993003.03187-2021. Print 2023 Mar. Eur Respir J. 2023. PMID: 36517177 Free PMC article. Review.
This expert group consensus statement emphasises the need for standardising the definition of progressive fibrosing interstitial lung diseases (F-ILDs), with an accurate initial diagnosis being of paramount importance in ensuring appropriate initial management. ...In concl …
This expert group consensus statement emphasises the need for standardising the definition of progressive fibrosing interstitial lung …
Targeting metabolic dysregulation for fibrosis therapy.
Zhao X, Kwan JYY, Yip K, Liu PP, Liu FF. Zhao X, et al. Nat Rev Drug Discov. 2020 Jan;19(1):57-75. doi: 10.1038/s41573-019-0040-5. Epub 2019 Sep 23. Nat Rev Drug Discov. 2020. PMID: 31548636 Review.
The disease burden caused by fibrosis is substantial, and there are currently no therapies that can prevent or reverse fibrosis. Metabolic alterations are increasingly recognized as an important pathogenic process that underlies fibrosis across many organ typ …
The disease burden caused by fibrosis is substantial, and there are currently no therapies that can prevent or reverse fibrosis …
Pathophysiological Mechanisms of Renal Fibrosis: A Review of Animal Models and Therapeutic Strategies.
Nogueira A, Pires MJ, Oliveira PA. Nogueira A, et al. In Vivo. 2017 Jan 2;31(1):1-22. doi: 10.21873/invivo.11019. In Vivo. 2017. PMID: 28064215 Free PMC article. Review.
There are many molecules and cells that are associated with progression of renal fibrosis e.g. angiotensin II (Ang II). Therefore, in order to understand the biopathology of renal fibrosis and for the evaluation of new treatments, the use of animal models is crucial …
There are many molecules and cells that are associated with progression of renal fibrosis e.g. angiotensin II (Ang II). Therefore, in …
Molecular Mechanisms of Pulmonary Fibrogenesis and Its Progression to Lung Cancer: A Review.
Kinoshita T, Goto T. Kinoshita T, et al. Int J Mol Sci. 2019 Mar 22;20(6):1461. doi: 10.3390/ijms20061461. Int J Mol Sci. 2019. PMID: 30909462 Free PMC article. Review.
Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, occurring primarily in older adults, and limited to the lungs. ...This review article reflects the current state of knowledge …
Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of …
49,157 results
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