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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1899 1
1922 1
1936 1
1939 1
1946 4
1947 6
1948 9
1949 3
1950 15
1951 13
1952 15
1953 19
1954 16
1955 22
1956 20
1957 26
1958 14
1959 19
1960 18
1961 27
1962 27
1963 47
1964 82
1965 54
1966 33
1967 61
1968 80
1969 67
1970 64
1971 89
1972 93
1973 89
1974 97
1975 223
1976 248
1977 232
1978 245
1979 284
1980 292
1981 289
1982 361
1983 416
1984 504
1985 515
1986 470
1987 516
1988 607
1989 792
1990 878
1991 925
1992 1007
1993 1069
1994 1119
1995 1168
1996 1280
1997 1319
1998 1385
1999 1494
2000 1639
2001 1771
2002 1911
2003 1972
2004 2171
2005 2395
2006 2503
2007 2691
2008 2949
2009 3279
2010 4023
2011 4068
2012 4670
2013 4988
2014 5275
2015 5868
2016 6245
2017 6663
2018 7075
2019 7900
2020 9100
2021 10077
2022 10062
2023 10465
2024 11646
2025 11211
2026 7128
2027 10

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152,185 results

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Page 1
Field cancerization: Definition, epidemiology, risk factors, and outcomes.
Willenbrink TJ, Ruiz ES, Cornejo CM, Schmults CD, Arron ST, Jambusaria-Pahlajani A. Willenbrink TJ, et al. J Am Acad Dermatol. 2020 Sep;83(3):709-717. doi: 10.1016/j.jaad.2020.03.126. Epub 2020 May 7. J Am Acad Dermatol. 2020. PMID: 32387665 Review.
Field cancerization was first described in 1953 when pathologic atypia was identified in clinically normal tissue surrounding oropharyngeal carcinomas. ...Since this initial study, field cancerization has been applied to numerous other epithelial tissu …
Field cancerization was first described in 1953 when pathologic atypia was identified in clinically normal tissue surrounding …
Field cancerization in breast cancer.
Gadaleta E, Thorn GJ, Ross-Adams H, Jones LJ, Chelala C. Gadaleta E, et al. J Pathol. 2022 Jul;257(4):561-574. doi: 10.1002/path.5902. Epub 2022 May 3. J Pathol. 2022. PMID: 35362092 Free PMC article. Review.
One leading theory to explain this phenomenon is the field cancerization theory. Under this hypothesis, tumors arise from a field of molecularly altered cells that create a permissive environment for malignant evolution, which can occur with or without morpho …
One leading theory to explain this phenomenon is the field cancerization theory. Under this hypothesis, tumors arise from a …
Field cancerization: Treatment.
Cornejo CM, Jambusaria-Pahlajani A, Willenbrink TJ, Schmults CD, Arron ST, Ruiz ES. Cornejo CM, et al. J Am Acad Dermatol. 2020 Sep;83(3):719-730. doi: 10.1016/j.jaad.2020.03.127. Epub 2020 May 6. J Am Acad Dermatol. 2020. PMID: 32387663 Review.
The goal of field cancerization treatment is to reduce the risk of developing keratinocyte carcinoma. ...The second article in this continuing medical education series provides a framework to guide evidence-based decision making for field cancerization …
The goal of field cancerization treatment is to reduce the risk of developing keratinocyte carcinoma. ...The second article in …
European consensus-based interdisciplinary guideline for diagnosis, treatment and prevention of actinic keratoses, epithelial UV-induced dysplasia and field cancerization on behalf of European Association of Dermato-Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Europeenne des Medecins Specialistes).
Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes). Kandolf L, et al. J Eur Acad Dermatol Venereol. 2024 Jun;38(6):1024-1047. doi: 10.1111/jdv.19897. Epub 2024 Mar 7. J Eur Acad Dermatol Venereol. 2024. PMID: 38451047 Free article.
The diagnosis of AK and field cancerization is made by clinical examination. Dermatoscopy, confocal microscopy, optical coherence tomography or line-field confocal-OCT can help in the differential diagnosis of AK and other skin neoplasms. ...Preventive …
The diagnosis of AK and field cancerization is made by clinical examination. Dermatoscopy, confocal microscopy, optical cohere …
Field Cancerization in NSCLC: A New Perspective on MicroRNAs in Macrophage Polarization.
Pirlog R, Cismaru A, Nutu A, Berindan-Neagoe I. Pirlog R, et al. Int J Mol Sci. 2021 Jan 13;22(2):746. doi: 10.3390/ijms22020746. Int J Mol Sci. 2021. PMID: 33451052 Free PMC article. Review.
Lung cancer is currently the first cause of cancer-related death. The major lung cancer subtype is non-small cell lung cancers (NSCLC), which accounts for approximatively 85% of cases. ...The progressive and diffuse alterations that occur in the respir …
Lung cancer is currently the first cause of cancer-related death. The major lung cancer subtype is non-small cell lung …
Colorectal Cancer in Inflammatory Bowel Disease: Mechanisms and Management.
Shah SC, Itzkowitz SH. Shah SC, et al. Gastroenterology. 2022 Mar;162(3):715-730.e3. doi: 10.1053/j.gastro.2021.10.035. Epub 2021 Oct 29. Gastroenterology. 2022. PMID: 34757143 Free PMC article. Review.
Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic inflammation is the driver of neoplastic progression, resulting in dysplastic precursor lesions that may …
Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC), despite decreases in CRC …
Field cancerization in the GI tract.
Graham TA, McDonald SA, Wright NA. Graham TA, et al. Future Oncol. 2011 Aug;7(8):981-93. doi: 10.2217/fon.11.70. Future Oncol. 2011. PMID: 21823893 Review.
Field cancerization, the replacement of the normal cell population by a histologically nondysplastic but protumorigenic mutant cell clone, underlies the development of many cancer types, and in this article we review field cancerization in the G …
Field cancerization, the replacement of the normal cell population by a histologically nondysplastic but protumorigenic mutant …
An evolutionary perspective on field cancerization.
Curtius K, Wright NA, Graham TA. Curtius K, et al. Nat Rev Cancer. 2018 Jan;18(1):19-32. doi: 10.1038/nrc.2017.102. Epub 2017 Dec 8. Nat Rev Cancer. 2018. PMID: 29217838 Review.
Here, we review the evidence of field cancerization across organs and examine the biological mechanisms that drive the evolutionary process that results in field creation. We discuss the clinical implications, principally, how measurements of the cancerize …
Here, we review the evidence of field cancerization across organs and examine the biological mechanisms that drive the evoluti …
Field cancerization: are multiple primary cancers monoclonal or polyclonal?
Carey TE. Carey TE. Ann Med. 1996 Jun;28(3):183-8. doi: 10.3109/07853899609033118. Ann Med. 1996. PMID: 8811160 Review.
Second primary cancers are a difficult problem in the upper aerodigestive tract and in several other organ sites. ...The strongest evidence shows that second primary cancers contain genetic markers identical to the original tumour. If additional study confirms that …
Second primary cancers are a difficult problem in the upper aerodigestive tract and in several other organ sites. ...The strongest ev …
Field cancerization in mammary carcinogenesis - Implications for prevention and treatment of breast cancer.
Rivenbark AG, Coleman WB. Rivenbark AG, et al. Exp Mol Pathol. 2012 Dec;93(3):391-8. doi: 10.1016/j.yexmp.2012.10.018. Epub 2012 Nov 6. Exp Mol Pathol. 2012. PMID: 23142414 Review.
Molecular studies suggest that the field of altered breast epithelial cells may carry cancer-promoting genetic mutations (or other molecular alterations) or cancer promoting epimutations (oncogenic alterations in the epigenome). ...In the example of a BRCA1-m …
Molecular studies suggest that the field of altered breast epithelial cells may carry cancer-promoting genetic mutations (or o …
152,185 results
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