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Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases.
Novoa B, Figueras A. Novoa B, et al. Among authors: figueras a. Adv Exp Med Biol. 2012;946:253-75. doi: 10.1007/978-1-4614-0106-3_15. Adv Exp Med Biol. 2012. PMID: 21948373 Review.
This temporal separation provides a suitable system to study the vertebrate innate immune response in vivo, independently from the adaptive immune response. ...In this review, we have tried to give some examples of the potential of zebrafish as a valuable model in i …
This temporal separation provides a suitable system to study the vertebrate innate immune response in vivo, independently from the ad …
Non-specific immune response of turbot, Scophthalmus maximus (L.), experimentally infected with a pathogenic Vibrio pelagius.
Villamil L, Figueras A, Aranguren R, Novoa B. Villamil L, et al. Among authors: figueras a. J Fish Dis. 2003 Jun;26(6):321-9. doi: 10.1046/j.1365-2761.2003.00464.x. J Fish Dis. 2003. PMID: 12899407
The effect of a pathogenic Vibrio pelagius, isolated during a mass mortality of turbot larvae, on the non-specific immune response of turbot, Scophthalmus maximus (L.), macrophages was studied both in vitro and in vivo. ...In contrast, incubation with ECPs at higher …
The effect of a pathogenic Vibrio pelagius, isolated during a mass mortality of turbot larvae, on the non-specific immune resp …
Zebrafish (Danio rerio) as a model for the study of vaccination against viral haemorrhagic septicemia virus (VHSV).
Novoa B, Romero A, Mulero V, Rodríguez I, Fernández I, Figueras A. Novoa B, et al. Among authors: figueras a. Vaccine. 2006 Jul 26;24(31-32):5806-16. doi: 10.1016/j.vaccine.2006.05.015. Epub 2006 May 30. Vaccine. 2006. PMID: 16777275
The recombinant virus rIHNV-Gvhsv GFP was able to protect against VHSV with a survival rate ranging from 20% to 60% depending of the vaccine dose. ...Zebrafish is a suitable animal model to study VHSV infection and immune (innate and adaptive) responses and, more im …
The recombinant virus rIHNV-Gvhsv GFP was able to protect against VHSV with a survival rate ranging from 20% to 60% depending of the …
Assessment of in vivo effects of the prestige fuel oil spill on the mediterranean mussel immune system.
Ordás MC, Albaigés J, Bayona JM, Ordás A, Figueras A. Ordás MC, et al. Among authors: figueras a. Arch Environ Contam Toxicol. 2007 Feb;52(2):200-6. doi: 10.1007/s00244-006-0058-7. Epub 2006 Nov 24. Arch Environ Contam Toxicol. 2007. PMID: 17180482
A laboratory experiment was carried out to study immune function alteration of the mussel Mytilus galloprovincialis when exposed to the Prestige oil spilled in November 2002 on the northwestern Spanish coast. ...
A laboratory experiment was carried out to study immune function alteration of the mussel Mytilus galloprovincialis when exposed to t
Analysis of differentially expressed genes in response to bacterial stimulation in hemocytes of the carpet-shell clam Ruditapes decussatus: identification of new antimicrobial peptides.
Gestal C, Costa M, Figueras A, Novoa B. Gestal C, et al. Among authors: figueras a. Gene. 2007 Dec 30;406(1-2):134-43. doi: 10.1016/j.gene.2007.07.030. Epub 2007 Aug 15. Gene. 2007. PMID: 17881157
Suppression subtractive hybridization was used to identify differentially expressed genes in hemocytes from carpet-shell clam Ruditapes decussatus stimulated with a mixture of dead bacterial strains. ...
Suppression subtractive hybridization was used to identify differentially expressed genes in hemocytes from carpet-shell clam Ruditapes decu …
Immune response of zebrafish (Danio rerio) against a newly isolated bacterial pathogen Aeromonas hydrophila.
Rodríguez I, Novoa B, Figueras A. Rodríguez I, et al. Among authors: figueras a. Fish Shellfish Immunol. 2008 Sep;25(3):239-49. doi: 10.1016/j.fsi.2008.05.002. Epub 2008 May 18. Fish Shellfish Immunol. 2008. PMID: 18640853
A strain of Aeromonas hydrophila associated with unusual mortalities in zebrafish (Danio rerio) culture facilities was isolated, identified and characterized. In challenge experiments, adult zebrafish were susceptible to infection by intraperitoneal (i.p.) injection with v
A strain of Aeromonas hydrophila associated with unusual mortalities in zebrafish (Danio rerio) culture facilities was isolated, iden
Recombinant infectious hematopoietic necrosis viruses induce protection for rainbow trout Oncorhynchus mykiss.
Romero A, Figueras A, Thoulouze MI, Bremont M, Novoa B. Romero A, et al. Among authors: figueras a. Dis Aquat Organ. 2008 Jul 7;80(2):123-35. doi: 10.3354/dao01932. Dis Aquat Organ. 2008. PMID: 18717065 Clinical Trial.
These studies suggest that the recombinant rIHNV-Gvhsv GFP is a promising candidate as a live recombinant vaccine and also provides a good model to further study viral pathogenicity and the molecular basis of protection against these viral infections....
These studies suggest that the recombinant rIHNV-Gvhsv GFP is a promising candidate as a live recombinant vaccine and also pro …
Differentially expressed genes of the carpet shell clam Ruditapes decussatus against Perkinsus olseni.
Prado-Alvarez M, Gestal C, Novoa B, Figueras A. Prado-Alvarez M, et al. Among authors: figueras a. Fish Shellfish Immunol. 2009 Jan;26(1):72-83. doi: 10.1016/j.fsi.2008.03.002. Epub 2008 Mar 18. Fish Shellfish Immunol. 2009. PMID: 19028428
A forward and a reverse subtraction were carried out to identify up- and down-regulated genes in both haemocytes and gills of clams naturally infected with P. olseni. ...A total of 305 differentially expressed sequences were obtained, 221 of them in haemocyte
A forward and a reverse subtraction were carried out to identify up- and down-regulated genes in both haemocytes and gills of
LPS response and tolerance in the zebrafish (Danio rerio).
Novoa B, Bowman TV, Zon L, Figueras A. Novoa B, et al. Among authors: figueras a. Fish Shellfish Immunol. 2009 Feb;26(2):326-31. doi: 10.1016/j.fsi.2008.12.004. Epub 2008 Dec 16. Fish Shellfish Immunol. 2009. PMID: 19110060 Free PMC article.
In addition, fish pretreated with a sublethal concentration of LPS did not die after exposure to a lethal concentration of LPS demonstrating, for the first time that LPS tolerance also happens in fish. ...Treating fish with AMD3100, a specific inhibitor of CX …
In addition, fish pretreated with a sublethal concentration of LPS did not die after exposure to a lethal concentration of LPS …
beta-Glucan administration enhances disease resistance and some innate immune responses in zebrafish (Danio rerio).
Rodríguez I, Chamorro R, Novoa B, Figueras A. Rodríguez I, et al. Among authors: figueras a. Fish Shellfish Immunol. 2009 Aug;27(2):369-73. doi: 10.1016/j.fsi.2009.02.007. Epub 2009 Feb 14. Fish Shellfish Immunol. 2009. PMID: 19232393
A single injection of 5 mgml(-1) of beta-glucan 6 days before challenge also enhanced significantly the survival against the infection. The treatment with beta-glucan increased the myelomonocytic cell population in the kidney at 6h postchallenge with A. hydrophila.
A single injection of 5 mgml(-1) of beta-glucan 6 days before challenge also enhanced significantly the survival against the infectio
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