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Development of resistance mechanisms to the growth-inhibitory effects of transforming growth factor-beta during tumor progression.
Filmus J, Kerbel RS. Filmus J, et al. Curr Opin Oncol. 1993 Jan;5(1):123-9. Curr Opin Oncol. 1993. PMID: 8427884 Review.
Insights into the key roles of proteoglycans in breast cancer biology and translational medicine.
Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Sanderson RD, Schaefer L, Iozzo RV, Karamanos NK. Theocharis AD, et al. Among authors: filmus j. Biochim Biophys Acta. 2015 Apr;1855(2):276-300. doi: 10.1016/j.bbcan.2015.03.006. Epub 2015 Mar 28. Biochim Biophys Acta. 2015. PMID: 25829250 Free PMC article. Review.
Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia.
Song J, Yuan C, Yang J, Liu T, Yao Y, Xiao X, Gajendran B, Xu D, Li YJ, Wang C, Liu W, Wen M, Spaner D, Filmus J, Zacksenhaus E, Zhang Y, Hao X, Ben-David Y. Song J, et al. Among authors: filmus j. FEBS J. 2018 Dec;285(24):4631-4645. doi: 10.1111/febs.14690. Epub 2018 Nov 20. FEBS J. 2018. PMID: 30387554 Free article.
The role of glypican-3 in the regulation of body size and cancer.
Filmus J, Capurro M. Filmus J, et al. Cell Cycle. 2008 Sep 15;7(18):2787-90. doi: 10.4161/cc.7.18.6672. Epub 2008 Sep 23. Cell Cycle. 2008. PMID: 18787398
Processing by convertases is required for glypican-3-induced inhibition of Hedgehog signaling.
Capurro M, Shi W, Izumikawa T, Kitagawa H, Filmus J. Capurro M, et al. Among authors: filmus j. J Biol Chem. 2015 Mar 20;290(12):7576-85. doi: 10.1074/jbc.M114.612705. Epub 2015 Feb 4. J Biol Chem. 2015. PMID: 25653284 Free PMC article.
Glypican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo.
Hartwig S, Hu MC, Cella C, Piscione T, Filmus J, Rosenblum ND. Hartwig S, et al. Among authors: filmus j. Mech Dev. 2005 Jul;122(7-8):928-38. doi: 10.1016/j.mod.2005.03.007. Mech Dev. 2005. PMID: 15925496
Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling.
Capurro MI, Xiang YY, Lobe C, Filmus J. Capurro MI, et al. Among authors: filmus j. Cancer Res. 2005 Jul 15;65(14):6245-54. doi: 10.1158/0008-5472.CAN-04-4244. Cancer Res. 2005. PMID: 16024626
Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.
Mawji IA, Simpson CD, Hurren R, Gronda M, Williams MA, Filmus J, Jonkman J, Da Costa RS, Wilson BC, Thomas MP, Reed JC, Glinsky GV, Schimmer AD. Mawji IA, et al. Among authors: filmus j. J Natl Cancer Inst. 2007 May 16;99(10):811-22. doi: 10.1093/jnci/djk182. J Natl Cancer Inst. 2007. PMID: 17505076
ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.
Liu Z, Li H, Derouet M, Filmus J, LaCasse EC, Korneluk RG, Kerbel RS, Rosen KV. Liu Z, et al. Among authors: filmus j. J Biol Chem. 2005 Nov 11;280(45):37383-92. doi: 10.1074/jbc.M503724200. Epub 2005 Aug 22. J Biol Chem. 2005. PMID: 16115895
Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.
Van Slyke P, Coll ML, Master Z, Kim H, Filmus J, Dumont DJ. Van Slyke P, et al. Among authors: filmus j. Mol Cell Biol. 2005 May;25(9):3831-41. doi: 10.1128/MCB.25.9.3831-3841.2005. Mol Cell Biol. 2005. PMID: 15831486 Free PMC article.
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