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Methotrexate as an alternative therapy for chronic calcium pyrophosphate deposition disease: an exploratory analysis.
Chollet-Janin A, Finckh A, Dudler J, Guerne PA. Chollet-Janin A, et al. Among authors: finckh a. Arthritis Rheum. 2007 Feb;56(2):688-92. doi: 10.1002/art.22389. Arthritis Rheum. 2007. PMID: 17265505

All patients reported an excellent clinical response, with marked improvement within a mean period of 7.4 weeks. A significant decrease in pain intensity (P < 0.0001), swollen and tender joint counts (P < 0.0001), and frequency of attacks was observed. ...CONC

All patients reported an excellent clinical response, with marked improvement within a mean period of 7.4 weeks. A significant …
Validation of questionnaire-based response criteria of treatment efficacy in the fibromyalgia syndrome.
Finckh A, Morabia A, Deluze C, Vischer T. Finckh A, et al. Arthritis Care Res. 1998 Apr;11(2):116-23. doi: 10.1002/art.1790110207. Arthritis Care Res. 1998. PMID: 9668734
Severity of the condition was assessed by a composite outcome score, a combination of different clinical outcome measures forming a clinical severity index. ...Moreover, the RPS demonstrated a good discriminant power in detecting patients with effectiv …
Severity of the condition was assessed by a composite outcome score, a combination of different clinical outcome measures form …
Neurophysiologic evidence for a central sensitization in patients with fibromyalgia.
Desmeules JA, Cedraschi C, Rapiti E, Baumgartner E, Finckh A, Cohen P, Dayer P, Vischer TL. Desmeules JA, et al. Among authors: finckh a. Arthritis Rheum. 2003 May;48(5):1420-9. doi: 10.1002/art.10893. Arthritis Rheum. 2003. PMID: 12746916 Clinical Trial.
METHODS: A total of 164 outpatients with FM who were attending a self-management program were invited to participate in the study. ...A cutoff value of <27.6 mA for NFR provided sensitivity of 73% and specificity of 80% for detecting central allodynia in t …
METHODS: A total of 164 outpatients with FM who were attending a self-management program were invited to participate in the st …
Fibromyalgia: a randomised, controlled trial of a treatment programme based on self management.
Cedraschi C, Desmeules J, Rapiti E, Baumgartner E, Cohen P, Finckh A, Allaz AF, Vischer TL. Cedraschi C, et al. Among authors: finckh a. Ann Rheum Dis. 2004 Mar;63(3):290-6. doi: 10.1136/ard.2002.004945. Ann Rheum Dis. 2004. PMID: 14962965 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the efficacy of a treatment programme for patients with fibromyalgia (FM) based on self management, using pool exercises and education. METHODS: Randomised controlled trial with a 6 month follow up to evaluate an outpatient multidisciplinary p …
OBJECTIVE: To evaluate the efficacy of a treatment programme for patients with fibromyalgia (FM) based on self management, using pool …
The cervical spine in calcium pyrophosphate dihydrate deposition disease. A prevalent case-control study.
Finckh A, Van Linthoudt D, Duvoisin B, Bovay P, Gerster JC. Finckh A, et al. J Rheumatol. 2004 Mar;31(3):545-9. J Rheumatol. 2004. PMID: 14994403
OBJECTIVE: To test the hypothesis that calcium pyrophosphate dihydrate (CPPD) deposition disease is a risk factor for neck pain. METHODS: A prevalent case-control study was conducted to assess cervical calcifications and neck pain between patients with and without k …
OBJECTIVE: To test the hypothesis that calcium pyrophosphate dihydrate (CPPD) deposition disease is a risk factor for neck pain. METH …
A randomized controlled trial of dehydroepiandrosterone in postmenopausal women with fibromyalgia.
Finckh A, Berner IC, Aubry-Rozier B, So AK. Finckh A, et al. J Rheumatol. 2005 Jul;32(7):1336-40. J Rheumatol. 2005. PMID: 15996074 Clinical Trial.
METHODS: In a double-blind crossover study, postmenopausal women with FM were randomized to DHEA supplementation (50 mg/day) or placebo for 3 months, with a one-month washout period in between. ...RESULTS: A total of 52 patients were randomized, 47 patients c …
METHODS: In a double-blind crossover study, postmenopausal women with FM were randomized to DHEA supplementation (50 mg/day) or place …
Evidence for differential acquired drug resistance to anti-tumour necrosis factor agents in rheumatoid arthritis.
Finckh A, Simard JF, Gabay C, Guerne PA; SCQM physicians. Finckh A, et al. Ann Rheum Dis. 2006 Jun;65(6):746-52. doi: 10.1136/ard.2005.045062. Epub 2005 Dec 8. Ann Rheum Dis. 2006. PMID: 16339288 Free PMC article.
Intensification of DMARD co-therapy and time to discontinuation of the three anti-TNF agents were analysed using a proportional hazards models. ...CONCLUSIONS: In this population, infliximab was associated with a higher risk of requiring intensification of DMARD co- …
Intensification of DMARD co-therapy and time to discontinuation of the three anti-TNF agents were analysed using a proportional hazar …
The effectiveness of anti-tumor necrosis factor therapy in preventing progressive radiographic joint damage in rheumatoid arthritis: a population-based study.
Finckh A, Simard JF, Duryea J, Liang MH, Huang J, Daneel S, Forster A, Gabay C, Guerne PA. Finckh A, et al. Arthritis Rheum. 2006 Jan;54(1):54-9. doi: 10.1002/art.21491. Arthritis Rheum. 2006. PMID: 16385495 Clinical Trial.
OBJECTIVE: To compare the effectiveness of 3 therapeutic strategies in preventing progressive joint damage, in a population-based cohort. ...RESULTS: A total of 372 patients treated with anti-tumor necrosis factor (TNF) therapies met the inclusion criteria. The base …
OBJECTIVE: To compare the effectiveness of 3 therapeutic strategies in preventing progressive joint damage, in a population-based coh …
Progression of radiographic joint damage in different eras: trends towards milder disease in rheumatoid arthritis are attributable to improved treatment.
Finckh A, Choi HK, Wolfe F. Finckh A, et al. Ann Rheum Dis. 2006 Sep;65(9):1192-7. doi: 10.1136/ard.2005.049338. Epub 2006 Mar 15. Ann Rheum Dis. 2006. PMID: 16540549 Free PMC article.
The radiographic disease progression in patients with disease onset in the 1970s, 1980s and 1990s was compared using a multivariate regression model for longitudinal data. ...CONCLUSION: These results suggest that the observed trend towards milder disease in rheumatoid art …
The radiographic disease progression in patients with disease onset in the 1970s, 1980s and 1990s was compared using a multivariate r …
Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: A meta-analysis.
Finckh A, Liang MH, van Herckenrode CM, de Pablo P. Finckh A, et al. Arthritis Rheum. 2006 Dec 15;55(6):864-72. doi: 10.1002/art.22353. Arthritis Rheum. 2006. PMID: 17139662
RESULTS: A total of 12 studies met the inclusion criteria. The pooled estimate of effects from these studies demonstrated a significant reduction of radiographic progression in patients treated early (-0.19 SMD, 95% confidence interval [95% CI] -0.34, -0.04), which …
RESULTS: A total of 12 studies met the inclusion criteria. The pooled estimate of effects from these studies demonstrated a si …
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