Fink MP - Search Results

1

Evidence that glutathione depletion is a mechanism responsible for the anti-inflammatory effects of ethyl pyruvate in cultured lipopolysaccharide-stimulated RAW 264.7 cells.

Song M, Kellum JA, Kaldas H, Fink MP. Song M, et al. Among authors: fink mp. J Pharmacol Exp Ther. 2004 Jan;308(1):307-16. doi: 10.1124/jpet.103.056622. Epub 2003 Oct 20. J Pharmacol Exp Ther. 2004. PMID: 14569076

2

Resuscitation with Ringer's ethyl pyruvate solution prolongs survival and modulates plasma cytokine and nitrite/nitrate concentrations in a rat model of lipopolysaccharide-induced shock.

Venkataraman R, Kellum JA, Song M, Fink MP. Venkataraman R, et al. Among authors: fink mp. Shock. 2002 Dec;18(6):507-12. doi: 10.1097/00024382-200212000-00004. Shock. 2002. PMID: 12462557

3

The phase 2 enzyme inducers ethacrynic acid, DL-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells.

Killeen ME, Englert JA, Stolz DB, Song M, Han Y, Delude RL, Kellum JA, Fink MP. Killeen ME, et al. Among authors: fink mp. J Pharmacol Exp Ther. 2006 Mar;316(3):1070-9. doi: 10.1124/jpet.105.092841. Epub 2005 Dec 28. J Pharmacol Exp Ther. 2006. PMID: 16382025

4

Ethyl pyruvate ameliorates intestinal epithelial barrier dysfunction in endotoxemic mice and immunostimulated caco-2 enterocytic monolayers.

Sappington PL, Han X, Yang R, Delude RL, Fink MP. Sappington PL, et al. Among authors: fink mp. J Pharmacol Exp Ther. 2003 Jan;304(1):464-76. doi: 10.1124/jpet.102.043182. J Pharmacol Exp Ther. 2003. PMID: 12490623

5

Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65.

Han Y, Englert JA, Yang R, Delude RL, Fink MP. Han Y, et al. Among authors: fink mp. J Pharmacol Exp Ther. 2005 Mar;312(3):1097-105. doi: 10.1124/jpet.104.079707. Epub 2004 Nov 3. J Pharmacol Exp Ther. 2005. PMID: 15525791

6

NAD+ ameliorates inflammation-induced epithelial barrier dysfunction in cultured enterocytes and mouse ileal mucosa.

Han X, Uchiyama T, Sappington PL, Yaguchi A, Yang R, Fink MP, Delude RL. Han X, et al. Among authors: fink mp. J Pharmacol Exp Ther. 2003 Nov;307(2):443-9. doi: 10.1124/jpet.103.056556. Epub 2003 Sep 15. J Pharmacol Exp Ther. 2003. PMID: 12975482

7

Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study.

Kellum JA, Kong L, Fink MP, Weissfeld LA, Yealy DM, Pinsky MR, Fine J, Krichevsky A, Delude RL, Angus DC; GenIMS Investigators. Kellum JA, et al. Among authors: fink mp. Arch Intern Med. 2007 Aug 13-27;167(15):1655-63. doi: 10.1001/archinte.167.15.1655. Arch Intern Med. 2007. PMID: 17698689 Free PMC article.

8

Ethyl pyruvate: a novel anti-inflammatory agent.

Fink MP. Fink MP. Crit Care Med. 2003 Jan;31(1 Suppl):S51-6. doi: 10.1097/00003246-200301001-00008. Crit Care Med. 2003. PMID: 12544977 Review.

9

The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.

Sappington PL, Cruz RJ Jr, Harada T, Yang R, Han Y, Englert JA, Ajami AA, Killeen ME, Delude RL, Fink MP. Sappington PL, et al. Among authors: fink mp. Biochem Pharmacol. 2005 Nov 25;70(11):1579-92. doi: 10.1016/j.bcp.2005.08.015. Epub 2005 Oct 13. Biochem Pharmacol. 2005. PMID: 16226725

10

Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis.

Yende S, D'Angelo G, Kellum JA, Weissfeld L, Fine J, Welch RD, Kong L, Carter M, Angus DC; GenIMS Investigators. Yende S, et al. Am J Respir Crit Care Med. 2008 Jun 1;177(11):1242-7. doi: 10.1164/rccm.200712-1777OC. Epub 2008 Mar 27. Am J Respir Crit Care Med. 2008. PMID: 18369199 Free PMC article.

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