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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.
Nemoto S, Fergusson MM, Finkel T. Nemoto S, et al. Among authors: finkel t. J Biol Chem. 2005 Apr 22;280(16):16456-60. doi: 10.1074/jbc.M501485200. Epub 2005 Feb 16. J Biol Chem. 2005. PMID: 15716268
Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle.
De La Fuente S, Fernandez-Sanz C, Vail C, Agra EJ, Holmstrom K, Sun J, Mishra J, Williams D, Finkel T, Murphy E, Joseph SK, Sheu SS, Csordás G. De La Fuente S, et al. Among authors: finkel t. J Biol Chem. 2016 Oct 28;291(44):23343-23362. doi: 10.1074/jbc.M116.755496. Epub 2016 Sep 16. J Biol Chem. 2016. PMID: 27637331 Free PMC article.
Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport.
Pfeiffer M, Kayzer EB, Yang X, Abramson E, Kenaston MA, Lago CU, Lo HH, Sedensky MM, Lunceford A, Clarke CF, Wu SJ, McLeod C, Finkel T, Morgan PG, Mills EM. Pfeiffer M, et al. Among authors: finkel t. J Biol Chem. 2011 Oct 28;286(43):37712-20. doi: 10.1074/jbc.M111.271452. Epub 2011 Aug 23. J Biol Chem. 2011. PMID: 21862587 Free PMC article.
Key proteins and pathways that regulate lifespan.
Pan H, Finkel T. Pan H, et al. Among authors: finkel t. J Biol Chem. 2017 Apr 21;292(16):6452-6460. doi: 10.1074/jbc.R116.771915. Epub 2017 Mar 6. J Biol Chem. 2017. PMID: 28264931 Free PMC article. Review.
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis.
Ahn BH, Kim HS, Song S, Lee IH, Liu J, Vassilopoulos A, Deng CX, Finkel T. Ahn BH, et al. Among authors: finkel t. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14447-52. doi: 10.1073/pnas.0803790105. Epub 2008 Sep 15. Proc Natl Acad Sci U S A. 2008. PMID: 18794531 Free PMC article.
Redox-dependent transcriptional regulation.
Liu H, Colavitti R, Rovira II, Finkel T. Liu H, et al. Among authors: finkel t. Circ Res. 2005 Nov 11;97(10):967-74. doi: 10.1161/01.RES.0000188210.72062.10. Circ Res. 2005. PMID: 16284189 Review.
Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor gamma Coactivator-1 alpha (PGC-1alpha).
Ichida M, Nemoto S, Finkel T. Ichida M, et al. Among authors: finkel t. J Biol Chem. 2002 Dec 27;277(52):50991-5. doi: 10.1074/jbc.M210262200. Epub 2002 Oct 22. J Biol Chem. 2002. PMID: 12397057
The emerging links between sirtuins and autophagy.
Lee IH, Yun J, Finkel T. Lee IH, et al. Among authors: finkel t. Methods Mol Biol. 2013;1077:259-71. doi: 10.1007/978-1-62703-637-5_17. Methods Mol Biol. 2013. PMID: 24014412 Free PMC article.
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T. Narayan N, et al. Among authors: finkel t. Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Nature. 2012. PMID: 23201684 Retracted.
Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.
Quijano C, Cao L, Fergusson MM, Romero H, Liu J, Gutkind S, Rovira II, Mohney RP, Karoly ED, Finkel T. Quijano C, et al. Among authors: finkel t. Cell Cycle. 2012 Apr 1;11(7):1383-92. doi: 10.4161/cc.19800. Epub 2012 Apr 1. Cell Cycle. 2012. PMID: 22421146 Free PMC article.
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