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The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, White AR, Crouch PJ, Lim S, Leong SL, Wilkins S, George J, Roberts BR, Pham CL, Liu X, Chiu FC, Shackleford DM, Powell AK, Masters CL, Bush AI, O'Keefe G, Culvenor JG, Cappai R, Cherny RA, Donnelly PS, Hill AF, Finkelstein DI, Barnham KJ. Hung LW, et al. Among authors: finkelstein di. J Exp Med. 2012 Apr 9;209(4):837-54. doi: 10.1084/jem.20112285. Epub 2012 Apr 2. J Exp Med. 2012. PMID: 22473957 Free PMC article.
Restoration of intestinal function in an MPTP model of Parkinson's Disease.
Ellett LJ, Hung LW, Munckton R, Sherratt NA, Culvenor J, Grubman A, Furness JB, White AR, Finkelstein DI, Barnham KJ, Lawson VA. Ellett LJ, et al. Among authors: finkelstein di. Sci Rep. 2016 Jul 29;6:30269. doi: 10.1038/srep30269. Sci Rep. 2016. PMID: 27471168 Free PMC article.
Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.
McKenzie-Nickson S, Chan J, Perez K, Hung LW, Cheng L, Sedjahtera A, Gunawan L, Adlard PA, Hayne DJ, McInnes LE, Donnelly PS, Finkelstein DI, Hill AF, Barnham KJ. McKenzie-Nickson S, et al. Among authors: finkelstein di. ACS Chem Neurosci. 2018 Nov 21;9(11):2731-2740. doi: 10.1021/acschemneuro.8b00161. Epub 2018 Jul 3. ACS Chem Neurosci. 2018. PMID: 29920069
Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species.
Foliaki ST, Lewis V, Finkelstein DI, Lawson V, Coleman HA, Senesi M, Islam AMT, Chen F, Sarros S, Roberts B, Adlard PA, Collins SJ. Foliaki ST, et al. Among authors: finkelstein di. PLoS Pathog. 2018 Aug 8;14(8):e1007214. doi: 10.1371/journal.ppat.1007214. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30089152 Free PMC article.
Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc.
Foliaki ST, Lewis V, Islam AMT, Ellett LJ, Senesi M, Finkelstein DI, Roberts B, Lawson VA, Adlard PA, Collins SJ. Foliaki ST, et al. Among authors: finkelstein di. PLoS Pathog. 2019 Apr 10;15(4):e1007712. doi: 10.1371/journal.ppat.1007712. eCollection 2019 Apr. PLoS Pathog. 2019. PMID: 30970042 Free PMC article.
The role of lipids in α-synuclein misfolding and neurotoxicity.
Ugalde CL, Lawson VA, Finkelstein DI, Hill AF. Ugalde CL, et al. Among authors: finkelstein di. J Biol Chem. 2019 Jun 7;294(23):9016-9028. doi: 10.1074/jbc.REV119.007500. Epub 2019 May 7. J Biol Chem. 2019. PMID: 31064841 Free PMC article. Review.
Chronic isolation stress is associated with increased colonic and motor symptoms in the A53T mouse model of Parkinson's disease.
Diwakarla S, Finkelstein DI, Constable R, Artaiz O, Di Natale M, McQuade RM, Lei E, Chai XY, Ringuet MT, Fothergill LJ, Lawson VA, Ellett LJ, Berger JP, Furness JB. Diwakarla S, et al. Among authors: di natale m, finkelstein di. Neurogastroenterol Motil. 2020 Mar;32(3):e13755. doi: 10.1111/nmo.13755. Epub 2019 Nov 10. Neurogastroenterol Motil. 2020. PMID: 31709672
198 results