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Metabolism, migration and memory in cytotoxic T cells.
Finlay D, Cantrell DA. Finlay D, et al. Nat Rev Immunol. 2011 Feb;11(2):109-17. doi: 10.1038/nri2888. Epub 2011 Jan 14. Nat Rev Immunol. 2011. PMID: 21233853 Free PMC article. Review.
Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.
Lipina C, Huang X, Finlay D, McManus EJ, Alessi DR, Sutherland C. Lipina C, et al. Among authors: finlay d. Biochem J. 2005 Dec 15;392(Pt 3):633-9. doi: 10.1042/BJ20051046. Biochem J. 2005. PMID: 16176184 Free PMC article.
A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression.
Finlay D, Ruiz-Alcaraz AJ, Lipina C, Perrier S, Sutherland C. Finlay D, et al. J Mol Endocrinol. 2006 Oct;37(2):227-37. doi: 10.1677/jme.1.02084. J Mol Endocrinol. 2006. PMID: 17032741
Notch-induced T cell development requires phosphoinositide-dependent kinase 1.
Kelly AP, Finlay DK, Hinton HJ, Clarke RG, Fiorini E, Radtke F, Cantrell DA. Kelly AP, et al. Among authors: finlay dk. EMBO J. 2007 Jul 25;26(14):3441-50. doi: 10.1038/sj.emboj.7601761. Epub 2007 Jun 28. EMBO J. 2007. PMID: 17599070 Free PMC article.
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking.
Sinclair LV, Finlay D, Feijoo C, Cornish GH, Gray A, Ager A, Okkenhaug K, Hagenbeek TJ, Spits H, Cantrell DA. Sinclair LV, et al. Among authors: finlay d. Nat Immunol. 2008 May;9(5):513-21. doi: 10.1038/ni.1603. Epub 2008 Apr 6. Nat Immunol. 2008. PMID: 18391955 Free PMC article.
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Sauer S, Bruno L, Hertweck A, Finlay D, Leleu M, Spivakov M, Knight ZA, Cobb BS, Cantrell D, O'Connor E, Shokat KM, Fisher AG, Merkenschlager M. Sauer S, et al. Among authors: finlay d. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7797-802. doi: 10.1073/pnas.0800928105. Epub 2008 May 28. Proc Natl Acad Sci U S A. 2008. PMID: 18509048 Free PMC article.
Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation.
Waugh C, Sinclair L, Finlay D, Bayascas JR, Cantrell D. Waugh C, et al. Among authors: finlay d. Mol Cell Biol. 2009 Nov;29(21):5952-62. doi: 10.1128/MCB.00585-09. Epub 2009 Aug 24. Mol Cell Biol. 2009. PMID: 19703999 Free PMC article.
Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes.
Finlay DK, Sinclair LV, Feijoo C, Waugh CM, Hagenbeek TJ, Spits H, Cantrell DA. Finlay DK, et al. J Exp Med. 2009 Oct 26;206(11):2441-54. doi: 10.1084/jem.20090219. Epub 2009 Oct 5. J Exp Med. 2009. PMID: 19808258 Free PMC article.
LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells.
Tamás P, Macintyre A, Finlay D, Clarke R, Feijoo-Carnero C, Ashworth A, Cantrell D. Tamás P, et al. Among authors: finlay d. Eur J Immunol. 2010 Jan;40(1):242-53. doi: 10.1002/eji.200939677. Eur J Immunol. 2010. PMID: 19830737 Free PMC article.
Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration.
Finlay D, Cantrell D. Finlay D, et al. Ann N Y Acad Sci. 2010 Jan;1183:149-57. doi: 10.1111/j.1749-6632.2009.05134.x. Ann N Y Acad Sci. 2010. PMID: 20146713 Free PMC article. Review.
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