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Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases.
Finlay DK. Finlay DK. Front Immunol. 2012 Aug 7;3:247. doi: 10.3389/fimmu.2012.00247. eCollection 2012. Front Immunol. 2012. PMID: 22891069 Free PMC article.
LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells.
Tamás P, Macintyre A, Finlay D, Clarke R, Feijoo-Carnero C, Ashworth A, Cantrell D. Tamás P, et al. Among authors: finlay d. Eur J Immunol. 2010 Jan;40(1):242-53. doi: 10.1002/eji.200939677. Eur J Immunol. 2010. PMID: 19830737 Free PMC article.
Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells.
Finlay DK, Kelly AP, Clarke R, Sinclair LV, Deak M, Alessi DR, Cantrell DA. Finlay DK, et al. J Immunol. 2010 Nov 15;185(10):5973-82. doi: 10.4049/jimmunol.1000827. Epub 2010 Oct 13. J Immunol. 2010. PMID: 20944007 Free PMC article.
Metabolism, migration and memory in cytotoxic T cells.
Finlay D, Cantrell DA. Finlay D, et al. Nat Rev Immunol. 2011 Feb;11(2):109-17. doi: 10.1038/nri2888. Epub 2011 Jan 14. Nat Rev Immunol. 2011. PMID: 21233853 Free PMC article. Review.
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
Finlay DK, Rosenzweig E, Sinclair LV, Feijoo-Carnero C, Hukelmann JL, Rolf J, Panteleyev AA, Okkenhaug K, Cantrell DA. Finlay DK, et al. J Exp Med. 2012 Dec 17;209(13):2441-53. doi: 10.1084/jem.20112607. Epub 2012 Nov 26. J Exp Med. 2012. PMID: 23183047 Free PMC article.
AMPKα1: a glucose sensor that controls CD8 T-cell memory.
Rolf J, Zarrouk M, Finlay DK, Foretz M, Viollet B, Cantrell DA. Rolf J, et al. Among authors: finlay dk. Eur J Immunol. 2013 Apr;43(4):889-96. doi: 10.1002/eji.201243008. Epub 2013 Feb 13. Eur J Immunol. 2013. PMID: 23310952 Free PMC article.
mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB.
Finlay DK. Finlay DK. Biochem Soc Trans. 2013 Apr;41(2):681-6. doi: 10.1042/BST20120359. Biochem Soc Trans. 2013. PMID: 23514176 Review.
IRF4 links antigen affinity to CD8+ T-cell metabolism.
Finlay D. Finlay D. Immunol Cell Biol. 2014 Jan;92(1):6-7. doi: 10.1038/icb.2013.72. Epub 2013 Oct 29. Immunol Cell Biol. 2014. PMID: 24165980 No abstract available.
Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells.
Zarrouk M, Finlay DK, Foretz M, Viollet B, Cantrell DA. Zarrouk M, et al. Among authors: finlay dk. PLoS One. 2014 Sep 2;9(9):e106710. doi: 10.1371/journal.pone.0106710. eCollection 2014. PLoS One. 2014. PMID: 25181053 Free PMC article.
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.
Donnelly RP, Loftus RM, Keating SE, Liou KT, Biron CA, Gardiner CM, Finlay DK. Donnelly RP, et al. Among authors: finlay dk. J Immunol. 2014 Nov 1;193(9):4477-84. doi: 10.4049/jimmunol.1401558. Epub 2014 Sep 26. J Immunol. 2014. PMID: 25261477 Free PMC article.
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