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661 results

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Page 1
Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy.
Tyrmi JS, Kaartokallio T, Lokki AI, Jääskeläinen T, Kortelainen E, Ruotsalainen S, Karjalainen J, Ripatti S, Kivioja A, Laisk T, Kettunen J, Pouta A, Kivinen K, Kajantie E, Heinonen S, Kere J, Laivuori H; FINNPEC Study Group, FinnGen Project, and the Estonian Biobank Research Team. Tyrmi JS, et al. JAMA Cardiol. 2023 Jul 1;8(7):674-683. doi: 10.1001/jamacardio.2023.1312. JAMA Cardiol. 2023. PMID: 37285119 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: This GWAS included meta-analyses in maternal preeclampsia and a combination phenotype encompassing maternal preeclampsia and preeclampsia or other maternal hypertensive disorders. ...Individuals with preeclampsia or other …
DESIGN, SETTING, AND PARTICIPANTS: This GWAS included meta-analyses in maternal preeclampsia and a combination phenotype encompassing …
Prediagnostic serum concentrations of per- and polyfluoroalkyl substances and risk of papillary thyroid cancer in the Finnish Maternity Cohort.
Madrigal JM, Troisi R, Surcel HM, Öhman H, Kivelä J, Kiviranta H, Rantakokko P, Koponen J, Medgyesi DN, Kitahara CM, McGlynn KA, Sampson J, Albert PS, Ward MH, Jones RR. Madrigal JM, et al. Int J Cancer. 2024 Mar 15;154(6):979-991. doi: 10.1002/ijc.34776. Epub 2023 Oct 30. Int J Cancer. 2024. PMID: 37902275
We conducted a nested case-control study of prediagnostic serum levels of 19 PFAS and papillary thyroid cancer (400 cases, 400 controls) in the Finnish Maternity Cohort (pregnancies 1986-2010; follow-up through 2016), individually matched on sample year and a …
We conducted a nested case-control study of prediagnostic serum levels of 19 PFAS and papillary thyroid cancer (400 cases, 400 controls) in …
Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism.
Vatanen T, Jabbar KS, Ruohtula T, Honkanen J, Avila-Pacheco J, Siljander H, Stražar M, Oikarinen S, Hyöty H, Ilonen J, Mitchell CM, Yassour M, Virtanen SM, Clish CB, Plichta DR, Vlamakis H, Knip M, Xavier RJ. Vatanen T, et al. Cell. 2022 Dec 22;185(26):4921-4936.e15. doi: 10.1016/j.cell.2022.11.023. Cell. 2022. PMID: 36563663 Free PMC article.
The perinatal period represents a critical window for cognitive and immune system development, promoted by maternal and infant gut microbiomes and their metabolites. Here, we tracked the co-development of microbiomes and metabolomes from late pregnancy to 1 year of age usi …
The perinatal period represents a critical window for cognitive and immune system development, promoted by maternal and infant gut mi …
Early-pregnancy sex steroid and thyroid function hormones, thyroid autoimmunity, and maternal papillary thyroid cancer incidence in the Finnish Maternity Cohort.
Kitahara CM, Surcel HM, Falk R, Pfeiffer RM, Männistö T, Gissler M, Trabert B. Kitahara CM, et al. Int J Cancer. 2024 Sep 15;155(6):1014-1022. doi: 10.1002/ijc.34974. Epub 2024 May 2. Int J Cancer. 2024. PMID: 38693841
We conducted a nested case-control study within the Finnish Maternity Cohort to evaluate pre-diagnostic sex steroid and thyroid function markers in relation to subsequent maternal papillary thyroid cancer. ...Our results suggest that thyroid autoimmuni …
We conducted a nested case-control study within the Finnish Maternity Cohort to evaluate pre-diagnostic sex steroid and …
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability.
Bjørk MH, Zoega H, Leinonen MK, Cohen JM, Dreier JW, Furu K, Gilhus NE, Gissler M, Hálfdánarson Ó, Igland J, Sun Y, Tomson T, Alvestad S, Christensen J. Bjørk MH, et al. JAMA Neurol. 2022 Jul 1;79(7):672-681. doi: 10.1001/jamaneurol.2022.1269. JAMA Neurol. 2022. PMID: 35639399
EXPOSURES: Prenatal exposure to ASM determined from maternal prescription fills between last menstrual period and birth. MAIN OUTCOMES AND MEASURES: We estimated cumulative incidence at age 8 years in exposed and unexposed children. ...In same-aged children of mothers
EXPOSURES: Prenatal exposure to ASM determined from maternal prescription fills between last menstrual period and birth. MAIN OUTCOME …
Sexually Transmitted Infections and Risk of Epithelial Ovarian Cancer: Results From the Finnish Maternity Cohort.
Skarga E, Surcel HM, Kaaks R, Waterboer T, Fortner RT. Skarga E, et al. J Infect Dis. 2023 Nov 28;228(11):1621-1629. doi: 10.1093/infdis/jiad171. J Infect Dis. 2023. PMID: 37196097 Free PMC article.
METHODS: We measured antibodies (Abs) to CT, MG, HSV-2, and HPV-16/18 in serum samples in a nested case-control study in the Finnish Maternity Cohort (N = 484 cases 1:1 matched to controls). Logistic regression was used to calculate relative risks (RRs) and 9 …
METHODS: We measured antibodies (Abs) to CT, MG, HSV-2, and HPV-16/18 in serum samples in a nested case-control study in the Finnish
Epstein-barr virus and multiple sclerosis risk in the finnish maternity cohort.
Munger KL, Hongell K, Cortese M, Åivo J, Soilu-Hänninen M, Surcel HM, Ascherio A. Munger KL, et al. Ann Neurol. 2019 Sep;86(3):436-442. doi: 10.1002/ana.25532. Epub 2019 Jul 3. Ann Neurol. 2019. PMID: 31226219 Free PMC article.
OBJECTIVE: To determine whether maternal Epstein-Barr virus (EBV) IgG antibody levels are associated with risk of multiple sclerosis (MS) in the offspring. METHODS: We conducted a prospective nested case-control study in the Finnish Maternity Cohort (F …
OBJECTIVE: To determine whether maternal Epstein-Barr virus (EBV) IgG antibody levels are associated with risk of multiple sclerosis …
Associations Between Maternal Antenatal Corticosteroid Treatment and Mental and Behavioral Disorders in Children.
Räikkönen K, Gissler M, Kajantie E. Räikkönen K, et al. JAMA. 2020 May 19;323(19):1924-1933. doi: 10.1001/jama.2020.3937. JAMA. 2020. PMID: 32427304 Free PMC article.
CONCLUSIONS AND RELEVANCE: In this population-based cohort study, exposure to maternal antenatal corticosteroid treatment was significantly associated with mental and behavioral disorders in children. These findings may help inform decisions about maternal an …
CONCLUSIONS AND RELEVANCE: In this population-based cohort study, exposure to maternal antenatal corticosteroid treatment was …
Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy.
Vegrim HM, Dreier JW, Alvestad S, Gilhus NE, Gissler M, Igland J, Leinonen MK, Tomson T, Sun Y, Zoega H, Christensen J, Bjørk MH. Vegrim HM, et al. JAMA Neurol. 2022 Nov 1;79(11):1130-1138. doi: 10.1001/jamaneurol.2022.2977. JAMA Neurol. 2022. PMID: 36156660 Free PMC article.
OBJECTIVE: To assess whether high-dose folic acid supplementation in mothers with epilepsy is associated with childhood cancer. DESIGN, SETTING, AND PARTICIPANTS: Observational cohort study conducted with nationwide registers in Denmark, Norway, and Sweden from 1997 …
OBJECTIVE: To assess whether high-dose folic acid supplementation in mothers with epilepsy is associated with childhood cancer. DESIG …
Sustained Cross-reactive Antibody Responses After Human Papillomavirus Vaccinations: Up to 12 Years Follow-up in the Finnish Maternity Cohort.
Kann H, Lehtinen M, Eriksson T, Surcel HM, Dillner J, Faust H. Kann H, et al. J Infect Dis. 2021 Jun 4;223(11):1992-2000. doi: 10.1093/infdis/jiaa617. J Infect Dis. 2021. PMID: 33009576
METHODS: Serum samples donated 7-12 years after immunization at age 16-17 years with bivalent (n = 730) or quadrivalent (n = 337) HPV vaccine were retrieved from the population-based Finnish Maternity Cohort biobank. Serum antibody levels against HPV types 6, …
METHODS: Serum samples donated 7-12 years after immunization at age 16-17 years with bivalent (n = 730) or quadrivalent (n = 337) HPV vaccin …
661 results