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A metabolic pathway for bile acid dehydroxylation by the gut microbiome.
Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA. Funabashi M, et al. Among authors: fischbach ma. Nature. 2020 Jun;582(7813):566-570. doi: 10.1038/s41586-020-2396-4. Epub 2020 Jun 17. Nature. 2020. PMID: 32555455 Free PMC article.
Role of dietary fiber in the recovery of the human gut microbiome and its metabolome.
Tanes C, Bittinger K, Gao Y, Friedman ES, Nessel L, Paladhi UR, Chau L, Panfen E, Fischbach MA, Braun J, Xavier RJ, Clish CB, Li H, Bushman FD, Lewis JD, Wu GD. Tanes C, et al. Among authors: fischbach ma. Cell Host Microbe. 2021 Mar 10;29(3):394-407.e5. doi: 10.1016/j.chom.2020.12.012. Epub 2021 Jan 12. Cell Host Microbe. 2021. PMID: 33440171
Gut microbes impact stroke severity via the trimethylamine N-oxide pathway.
Zhu W, Romano KA, Li L, Buffa JA, Sangwan N, Prakash P, Tittle AN, Li XS, Fu X, Androjna C, DiDonato AJ, Brinson K, Trapp BD, Fischbach MA, Rey FE, Hajjar AM, DiDonato JA, Hazen SL. Zhu W, et al. Among authors: fischbach ma. Cell Host Microbe. 2021 Jul 14;29(7):1199-1208.e5. doi: 10.1016/j.chom.2021.05.002. Epub 2021 Jun 16. Cell Host Microbe. 2021. PMID: 34139173
A metabolomics pipeline for the mechanistic interrogation of the gut microbiome.
Han S, Van Treuren W, Fischer CR, Merrill BD, DeFelice BC, Sanchez JM, Higginbottom SK, Guthrie L, Fall LA, Dodd D, Fischbach MA, Sonnenburg JL. Han S, et al. Among authors: fischbach ma. Nature. 2021 Jul;595(7867):415-420. doi: 10.1038/s41586-021-03707-9. Epub 2021 Jul 14. Nature. 2021. PMID: 34262212
Bifidobacterium alters the gut microbiota and modulates the functional metabolism of T regulatory cells in the context of immune checkpoint blockade.
Sun S, Luo L, Liang W, Yin Q, Guo J, Rush AM, Lv Z, Liang Q, Fischbach MA, Sonnenburg JL, Dodd D, Davis MM, Wang F. Sun S, et al. Among authors: fischbach ma. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27509-27515. doi: 10.1073/pnas.1921223117. Epub 2020 Oct 19. Proc Natl Acad Sci U S A. 2020. PMID: 33077598 Free PMC article.
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome.
Nayfach S, Páez-Espino D, Call L, Low SJ, Sberro H, Ivanova NN, Proal AD, Fischbach MA, Bhatt AS, Hugenholtz P, Kyrpides NC. Nayfach S, et al. Among authors: fischbach ma. Nat Microbiol. 2021 Jul;6(7):960-970. doi: 10.1038/s41564-021-00928-6. Epub 2021 Jun 24. Nat Microbiol. 2021. PMID: 34168315 Free PMC article.
Depletion of microbiome-derived molecules in the host using Clostridium genetics.
Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA. Guo CJ, et al. Among authors: fischbach ma. Science. 2019 Dec 13;366(6471):eaav1282. doi: 10.1126/science.aav1282. Science. 2019. PMID: 31831639 Free PMC article.
MAIT cells are imprinted by the microbiota in early life and promote tissue repair.
Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, Roy S, Cua DJ, Adams EJ, Bhandoola A, Scharschmidt TC, Aubé J, Fischbach MA, Belkaid Y. Constantinides MG, et al. Among authors: fischbach ma. Science. 2019 Oct 25;366(6464):eaax6624. doi: 10.1126/science.aax6624. Science. 2019. PMID: 31649166 Free PMC article.
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