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Depletion of microbiome-derived molecules in the host using Clostridium genetics.
Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA. Guo CJ, et al. Among authors: fischer cr. Science. 2019 Dec 13;366(6471):eaav1282. doi: 10.1126/science.aav1282. Science. 2019. PMID: 31831639 Free PMC article.
A metabolomics pipeline for the mechanistic interrogation of the gut microbiome.
Han S, Van Treuren W, Fischer CR, Merrill BD, DeFelice BC, Sanchez JM, Higginbottom SK, Guthrie L, Fall LA, Dodd D, Fischbach MA, Sonnenburg JL. Han S, et al. Among authors: fischer cr. Nature. 2021 Jul;595(7867):415-420. doi: 10.1038/s41586-021-03707-9. Epub 2021 Jul 14. Nature. 2021. PMID: 34262212 Free PMC article.
Oxidative ornithine metabolism supports non-inflammatory C. difficile colonization.
Pruss KM, Enam F, Battaglioli E, DeFeo M, Diaz OR, Higginbottom SK, Fischer CR, Hryckowian AJ, Van Treuren W, Dodd D, Kashyap P, Sonnenburg JL. Pruss KM, et al. Among authors: fischer cr. Nat Metab. 2022 Jan;4(1):19-28. doi: 10.1038/s42255-021-00506-4. Epub 2022 Jan 6. Nat Metab. 2022. PMID: 34992297 Free PMC article.
HEx: A heterologous expression platform for the discovery of fungal natural products.
Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME. Harvey CJB, et al. Among authors: fischer cr. Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr. Sci Adv. 2018. PMID: 29651464 Free PMC article.
112 results