Fischer JB - Search Results

1

Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands.

Glennon RA, Yousif MY, Ismaiel AM, el-Ashmawy MB, Herndon JL, Fischer JB, Server AC, Howie KJ. Glennon RA, et al. Among authors: fischer jb. J Med Chem. 1991 Dec;34(12):3360-5. doi: 10.1021/jm00116a003. J Med Chem. 1991. PMID: 1662725

2

Probing the proposed phenyl-A region of the sigma-1 receptor.

Ablordeppey SY, Fischer JB, Law H, Glennon RA. Ablordeppey SY, et al. Among authors: fischer jb. Bioorg Med Chem. 2002 Aug;10(8):2759-65. doi: 10.1016/s0968-0896(02)00096-2. Bioorg Med Chem. 2002. PMID: 12057665

3

Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors.

Glennon RA, Ismaiel AM, Smith JD, Yousif M, el-Ashmawy M, Herndon JL, Fischer JB, Howie KJ, Server AC. Glennon RA, et al. Among authors: fischer jb. J Med Chem. 1991 Jun;34(6):1855-9. doi: 10.1021/jm00110a015. J Med Chem. 1991. PMID: 1648139

4

Identification and exploitation of the sigma-opiate pharmacophore.

Glennon RA, Smith JD, Ismaiel AM, el-Ashmawy M, Battaglia G, Fischer JB. Glennon RA, et al. Among authors: fischer jb. J Med Chem. 1991 Mar;34(3):1094-8. doi: 10.1021/jm00107a033. J Med Chem. 1991. PMID: 1848295

5

Synthesis and structure-activity relationships of N,N'-di-o-tolylguanidine analogues, high-affinity ligands for the haloperidol-sensitive sigma receptor.

Scherz MW, Fialeix M, Fischer JB, Reddy NL, Server AC, Sonders MS, Tester BC, Weber E, Wong ST, Keana JF. Scherz MW, et al. Among authors: fischer jb. J Med Chem. 1990 Sep;33(9):2421-9. doi: 10.1021/jm00171a016. J Med Chem. 1990. PMID: 1975275

6

Structural features important for sigma 1 receptor binding.

Glennon RA, Ablordeppey SY, Ismaiel AM, el-Ashmawy MB, Fischer JB, Howie KB. Glennon RA, et al. Among authors: fischer jb. J Med Chem. 1994 Apr 15;37(8):1214-9. doi: 10.1021/jm00034a020. J Med Chem. 1994. PMID: 8164264

7

Is a nitrogen atom an important pharmacophoric element in sigma ligand binding?

Ablordeppey SY, Fischer JB, Glennon RA. Ablordeppey SY, et al. Among authors: fischer jb. Bioorg Med Chem. 2000 Aug;8(8):2105-11. doi: 10.1016/s0968-0896(00)00148-6. Bioorg Med Chem. 2000. PMID: 11003156

8

Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties.

Keana JF, McBurney RN, Scherz MW, Fischer JB, Hamilton PN, Smith SM, Server AC, Finkbeiner S, Stevens CF, Jahr C, et al. Keana JF, et al. Among authors: fischer jb. Proc Natl Acad Sci U S A. 1989 Jul;86(14):5631-5. doi: 10.1073/pnas.86.14.5631. Proc Natl Acad Sci U S A. 1989. PMID: 2546162 Free PMC article.

9

Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist.

Reddy NL, Hu LY, Cotter RE, Fischer JB, Wong WJ, McBurney RN, Weber E, Holmes DL, Wong ST, Prasad R, et al. Reddy NL, et al. Among authors: fischer jb. J Med Chem. 1994 Jan 21;37(2):260-7. doi: 10.1021/jm00028a009. J Med Chem. 1994. PMID: 8295213

10

Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.

Hu LY, Guo J, Magar SS, Fischer JB, Burke-Howie KJ, Durant GJ. Hu LY, et al. Among authors: fischer jb. J Med Chem. 1997 Dec 19;40(26):4281-9. doi: 10.1021/jm970459c. J Med Chem. 1997. PMID: 9435897

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