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The discovery of receptor tyrosine kinases: targets for cancer therapy.
Gschwind A, Fischer OM, Ullrich A. Gschwind A, et al. Nat Rev Cancer. 2004 May;4(5):361-70. doi: 10.1038/nrc1360. Nat Rev Cancer. 2004. PMID: 15122207 Review. No abstract available.
Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.
Hart S, Fischer OM, Ullrich A. Hart S, et al. Cancer Res. 2004 Mar 15;64(6):1943-50. doi: 10.1158/0008-5472.can-03-3720. Cancer Res. 2004. PMID: 15026328
Beyond Herceptin and Gleevec.
Fischer OM, Streit S, Hart S, Ullrich A. Fischer OM, et al. Curr Opin Chem Biol. 2003 Aug;7(4):490-5. doi: 10.1016/s1367-5931(03)00082-6. Curr Opin Chem Biol. 2003. PMID: 12941424 Review.
GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways.
Hart S, Fischer OM, Prenzel N, Zwick-Wallasch E, Schneider M, Hennighausen L, Ullrich A. Hart S, et al. Among authors: fischer om. Biol Chem. 2005 Sep;386(9):845-55. doi: 10.1515/BC.2005.099. Biol Chem. 2005. PMID: 16164409
Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor.
Fischer OM, Hart S, Gschwind A, Prenzel N, Ullrich A. Fischer OM, et al. Mol Cell Biol. 2004 Jun;24(12):5172-83. doi: 10.1128/MCB.24.12.5172-5183.2004. Mol Cell Biol. 2004. PMID: 15169883 Free PMC article.
Dissecting the epidermal growth factor receptor signal transactivation pathway.
Fischer OM, Hart S, Ullrich A. Fischer OM, et al. Methods Mol Biol. 2006;327:85-97. doi: 10.1385/1-59745-012-X:85. Methods Mol Biol. 2006. PMID: 16780214
EGFR signal transactivation in cancer cells.
Fischer OM, Hart S, Gschwind A, Ullrich A. Fischer OM, et al. Biochem Soc Trans. 2003 Dec;31(Pt 6):1203-8. doi: 10.1042/bst0311203. Biochem Soc Trans. 2003. PMID: 14641026 Review.
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