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Viral ion channels: structure and function.
Fischer WB, Sansom MS. Fischer WB, et al. Biochim Biophys Acta. 2002 Mar 19;1561(1):27-45. doi: 10.1016/s0304-4157(01)00009-0. Biochim Biophys Acta. 2002. PMID: 11988179 Review.
Biophysical characterization of Vpu from HIV-1 suggests a channel-pore dualism.
Mehnert T, Routh A, Judge PJ, Lam YH, Fischer D, Watts A, Fischer WB. Mehnert T, et al. Among authors: fischer d, fischer wb. Proteins. 2008 Mar;70(4):1488-97. doi: 10.1002/prot.21642. Proteins. 2008. PMID: 17910056 Free PMC article.
Towards a mechanism of function of the viral ion channel Vpu from HIV-1.
Mehnert T, Lam YH, Judge PJ, Routh A, Fischer D, Watts A, Fischer WB. Mehnert T, et al. Among authors: fischer d, fischer wb. J Biomol Struct Dyn. 2007 Jun;24(6):589-96. doi: 10.1080/07391102.2007.10507148. J Biomol Struct Dyn. 2007. PMID: 17508781
Drug-protein interaction with Vpu from HIV-1: proposing binding sites for amiloride and one of its derivatives.
Kim CG, Lemaitre V, Watts A, Fischer WB. Kim CG, et al. Among authors: fischer wb. Anal Bioanal Chem. 2006 Dec;386(7-8):2213-7. doi: 10.1007/s00216-006-0832-4. Epub 2006 Nov 3. Anal Bioanal Chem. 2006. PMID: 17082882
Full length Vpu from HIV-1: combining molecular dynamics simulations with NMR spectroscopy.
Lemaitre V, Willbold D, Watts A, Fischer WB. Lemaitre V, et al. Among authors: fischer wb. J Biomol Struct Dyn. 2006 Apr;23(5):485-96. doi: 10.1080/07391102.2006.10507074. J Biomol Struct Dyn. 2006. PMID: 16494498
Interaction of amiloride and one of its derivatives with Vpu from HIV-1: a molecular dynamics simulation.
Lemaitre V, Ali R, Kim CG, Watts A, Fischer WB. Lemaitre V, et al. Among authors: fischer wb. FEBS Lett. 2004 Apr 9;563(1-3):75-81. doi: 10.1016/S0014-5793(04)00251-0. FEBS Lett. 2004. PMID: 15063726
Vpu from HIV-1 on an atomic scale: experiments and computer simulations.
Fischer WB. Fischer WB. FEBS Lett. 2003 Sep 18;552(1):39-46. doi: 10.1016/s0014-5793(03)00782-8. FEBS Lett. 2003. PMID: 12972150 Review.
Molecular dynamics simulations on the first two helices of Vpu from HIV-1.
Sramala I, Lemaitre V, Faraldo-Gómez JD, Vincent S, Watts A, Fischer WB. Sramala I, et al. Among authors: fischer wb. Biophys J. 2003 May;84(5):3276-84. doi: 10.1016/S0006-3495(03)70052-6. Biophys J. 2003. PMID: 12719257 Free PMC article.
Bundles consisting of extended transmembrane segments of Vpu from HIV-1: computer simulations and conductance measurements.
Cordes FS, Tustian AD, Sansom MS, Watts A, Fischer WB. Cordes FS, et al. Among authors: fischer wb. Biochemistry. 2002 Jun 11;41(23):7359-65. doi: 10.1021/bi025518p. Biochemistry. 2002. PMID: 12044168
Amantadine blocks channel activity of the transmembrane segment of the NB protein from influenza B.
Fischer WB, Pitkeathly M, Sansom MS. Fischer WB, et al. Eur Biophys J. 2001 Oct;30(6):416-20. doi: 10.1007/s002490100157. Eur Biophys J. 2001. PMID: 11718294
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