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COX-2 inhibitors and cardiovascular risk.
Funk CD, FitzGerald GA. Funk CD, et al. J Cardiovasc Pharmacol. 2007 Nov;50(5):470-9. doi: 10.1097/FJC.0b013e318157f72d. J Cardiovasc Pharmacol. 2007. PMID: 18030055 Review.
Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Cannon CP, Curtis SP, FitzGerald GA, Krum H, Kaur A, Bolognese JA, Reicin AS, Bombardier C, Weinblatt ME, van der Heijde D, Erdmann E, Laine L; MEDAL Steering Committee. Cannon CP, et al. Lancet. 2006 Nov 18;368(9549):1771-81. doi: 10.1016/S0140-6736(06)69666-9. Lancet. 2006. PMID: 17113426
COX-2 in play at the AHA and the FDA.
FitzGerald GA. FitzGerald GA. Trends Pharmacol Sci. 2007 Jul;28(7):303-7. doi: 10.1016/ Epub 2007 Jun 18. Trends Pharmacol Sci. 2007. PMID: 17573128
Controversies in COX-2 selective inhibition.
Simon LS, Smolen JS, Abramson SB, Appel G, Bombardier C, Brater DC, Breedveld FC, Brune K, Burmester GR, Crofford LJ, Dougados M, DuBois RN, Fitzgerald GA, Frishman W, García Rodríguez LA, Hochberg MC, Kalden JR, Laine L, Langman MJ, Prescott SM, van de Putte LB, Whelton A, White WB, Willaims GH. Simon LS, et al. J Rheumatol. 2002 Jul;29(7):1501-10. J Rheumatol. 2002. PMID: 12136912 Review. No abstract available.
The Cardiovascular Pharmacology of Nonsteroidal Anti-Inflammatory Drugs.
Grosser T, Ricciotti E, FitzGerald GA. Grosser T, et al. Trends Pharmacol Sci. 2017 Aug;38(8):733-748. doi: 10.1016/ Epub 2017 Jun 23. Trends Pharmacol Sci. 2017. PMID: 28651847 Free PMC article. Review.
Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness.
Wang M, Cooper PR, Jiang M, Zhao H, Hui Y, Yao Y, Tate JC, Damera G, Lawson JA, Jester WF Jr, Haczku A, Panettieri RA Jr, FitzGerald GA. Wang M, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):63-8. doi: 10.1124/jpet.110.166678. Epub 2010 Apr 6. J Pharmacol Exp Ther. 2010. PMID: 20371706 Free PMC article.
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