Fitzpatrick FA - Search Results

1

Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.

Covey TM, Edes K, Fitzpatrick FA. Covey TM, et al. Among authors: fitzpatrick fa. Oncogene. 2007 Aug 23;26(39):5784-92. doi: 10.1038/sj.onc.1210391. Epub 2007 Mar 19. Oncogene. 2007. PMID: 17369849

2

Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.

Slattery ML, Herrick JS, Lundgreen A, Fitzpatrick FA, Curtin K, Wolff RK. Slattery ML, et al. Among authors: fitzpatrick fa. Carcinogenesis. 2010 Sep;31(9):1604-11. doi: 10.1093/carcin/bgq142. Epub 2010 Jul 9. Carcinogenesis. 2010. PMID: 20622004 Free PMC article.

3

Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function.

Doyle K, Fitzpatrick FA. Doyle K, et al. Among authors: fitzpatrick fa. J Biol Chem. 2010 Jun 4;285(23):17417-24. doi: 10.1074/jbc.M109.089250. Epub 2010 Apr 12. J Biol Chem. 2010. PMID: 20385560 Free PMC article.

4

Influence of myeloperoxidase on colon tumor occurrence in inflamed versus non-inflamed colons of Apc(Min/+) mice.

Al-Salihi M, Reichert E, Fitzpatrick FA. Al-Salihi M, et al. Among authors: fitzpatrick fa. Redox Biol. 2015 Dec;6:218-225. doi: 10.1016/j.redox.2015.07.013. Epub 2015 Jul 29. Redox Biol. 2015. PMID: 26262998 Free PMC article.

5

Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles.

Cassidy PB, Edes K, Nelson CC, Parsawar K, Fitzpatrick FA, Moos PJ. Cassidy PB, et al. Among authors: fitzpatrick fa. Carcinogenesis. 2006 Dec;27(12):2538-49. doi: 10.1093/carcin/bgl111. Epub 2006 Jun 15. Carcinogenesis. 2006. PMID: 16777982

6

Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: cyclopentenone prostaglandins and 4-hydroxy-2-nonenal covalently modify and inhibit the AMP-kinase kinase that modulates cellular energy homeostasis and protein translation.

Wagner TM, Mullally JE, Fitzpatrick FA. Wagner TM, et al. Among authors: fitzpatrick fa. J Biol Chem. 2006 Feb 3;281(5):2598-604. doi: 10.1074/jbc.M509723200. Epub 2005 Nov 25. J Biol Chem. 2006. PMID: 16311241

7

Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis.

Moos PJ, Fitzpatrick FA. Moos PJ, et al. Among authors: fitzpatrick fa. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3896-901. doi: 10.1073/pnas.95.7.3896. Proc Natl Acad Sci U S A. 1998. PMID: 9520464 Free PMC article.

8

Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes.

Yu MK, Moos PJ, Cassidy P, Wade M, Fitzpatrick FA. Yu MK, et al. Among authors: fitzpatrick fa. J Biol Chem. 2004 Jul 2;279(27):28028-35. doi: 10.1074/jbc.M313939200. Epub 2004 Apr 27. J Biol Chem. 2004. PMID: 15123685

9

Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins.

Moos PJ, Edes K, Fitzpatrick FA. Moos PJ, et al. Among authors: fitzpatrick fa. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9215-20. doi: 10.1073/pnas.160241897. Proc Natl Acad Sci U S A. 2000. PMID: 10908664 Free PMC article.

10

Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology.

Slattery ML, Fitzpatrick FA. Slattery ML, et al. Among authors: fitzpatrick fa. Cancer Prev Res (Phila). 2009 Nov;2(11):922-30. doi: 10.1158/1940-6207.CAPR-08-0191. Cancer Prev Res (Phila). 2009. PMID: 19892662 Free PMC article. Review.

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