Fjellström O - Search Results

1

Analysis of selective regions in the active sites of human cytochromes P450, 2C8, 2C9, 2C18, and 2C19 homology models using GRID/CPCA.

Ridderström M, Zamora I, Fjellström O, Andersson TB. Ridderström M, et al. Among authors: fjellstrom o. J Med Chem. 2001 Nov 22;44(24):4072-81. doi: 10.1021/jm0109107. J Med Chem. 2001. PMID: 11708911

2

Domains, specific residues and conformational states involved in hydride ion transfer and proton pumping by nicotinamide nucleotide transhydrogenase from Escherichia coli.

Rydström J, Hu X, Fjellström O, Meuller J, Zhang J, Johansson C, Bizouarn T. Rydström J, et al. Among authors: fjellstrom o. Biochim Biophys Acta. 1998 Jun 10;1365(1-2):10-6. doi: 10.1016/s0005-2728(98)00038-3. Biochim Biophys Acta. 1998. PMID: 9693716 Free article. Review.

3

Mapping of residues in the NADP(H)-binding site of proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. A study of structure and function.

Fjellström O, Axelsson M, Bizouarn T, Hu X, Johansson C, Meuller J, Rydström J. Fjellström O, et al. J Biol Chem. 1999 Mar 5;274(10):6350-9. doi: 10.1074/jbc.274.10.6350. J Biol Chem. 1999. PMID: 10037725 Free article.

4

Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin.

Hanessian S, Ersmark K, Wang X, Del Valle JR, Blomberg N, Xue Y, Fjellström O. Hanessian S, et al. Among authors: fjellstrom o. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3480-5. doi: 10.1016/j.bmcl.2007.03.075. Epub 2007 Mar 27. Bioorg Med Chem Lett. 2007. PMID: 17428662

5

Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.

Alstermark C, Amin K, Dinn SR, Elebring T, Fjellström O, Fitzpatrick K, Geiss WB, Gottfries J, Guzzo PR, Harding JP, Holmén A, Kothare M, Lehmann A, Mattsson JP, Nilsson K, Sundén G, Swanson M, von Unge S, Woo AM, Wyle MJ, Zheng X. Alstermark C, et al. Among authors: fjellstrom o. J Med Chem. 2008 Jul 24;51(14):4315-20. doi: 10.1021/jm701425k. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578471

6

Pharmacodynamic-pharmacokinetic integration as a guide to medicinal chemistry.

Gabrielsson J, Fjellström O, Ulander J, Rowley M, Van Der Graaf PH. Gabrielsson J, et al. Among authors: fjellstrom o. Curr Top Med Chem. 2011;11(4):404-18. doi: 10.2174/156802611794480864. Curr Top Med Chem. 2011. PMID: 21320067 Review.

7

Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation.

Fjellström O, Deinum J, Sjögren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D. Fjellström O, et al. J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15. J Biol Chem. 2013. PMID: 23155046 Free PMC article.

8

Potent fibrinolysis inhibitor discovered by shape and electrostatic complementarity to the drug tranexamic acid.

Boström J, Grant JA, Fjellström O, Thelin A, Gustafsson D. Boström J, et al. Among authors: fjellstrom o. J Med Chem. 2013 Apr 25;56(8):3273-80. doi: 10.1021/jm301818g. Epub 2013 Apr 10. J Med Chem. 2013. PMID: 23521080

9

Design, synthesis, and SAR of a series of activated protein C (APC) inhibitors with selectivity against thrombin for the treatment of haemophilia.

Bach P, Knerr L, Fjellström O, Hansson K, Mattsson C, Gustafsson D. Bach P, et al. Among authors: fjellstrom o. Bioorg Med Chem Lett. 2014 Feb 1;24(3):821-7. doi: 10.1016/j.bmcl.2013.12.094. Epub 2013 Dec 29. Bioorg Med Chem Lett. 2014. PMID: 24418773

10

Lactam sulfonamides as potent inhibitors of the Kv1.5 potassium ion channel.

Olsson RI, Jacobson I, Iliefski T, Boström J, Davidsson Ö, Fjellström O, Björe A, Olsson C, Sundell J, Gran U, Gyll J, Malmberg J, Hidestål O, Emtenäs H, Svensson T, Yuan ZQ, Strandlund G, Åstrand A, Lindhardt E, Linhardt G, Forsström E, Högberg Å, Persson F, Andersson B, Rönnborg A, Löfberg B. Olsson RI, et al. Among authors: fjellstrom o. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1269-73. doi: 10.1016/j.bmcl.2014.01.067. Epub 2014 Jan 30. Bioorg Med Chem Lett. 2014. PMID: 24513046

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