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Alterations in the central nervous alpha 2-adrenoceptor system under chronic psychosocial stress.
Flügge G. Flügge G. Neuroscience. 1996 Nov;75(1):187-96. doi: 10.1016/0306-4522(96)00292-8. Neuroscience. 1996. PMID: 8923533
It has recently been shown for the tree shrew that after 10 days of psychosocial stress, when the central nervous noradrenergic and adrenergic systems are highly activated, alpha 2-adrenoceptors are down-regulated in brain regions which are involved in the regulation of autonomic …
It has recently been shown for the tree shrew that after 10 days of psychosocial stress, when the central nervous noradrenergic and adrenerg …
Nocturnal hyperthermia induced by social stress in male tree shrews: relation to low testosterone and effects of age.
Kohlhause S, Hoffmann K, Schlumbohm C, Fuchs E, Flügge G. Kohlhause S, et al. Physiol Behav. 2011 Oct 24;104(5):786-95. doi: 10.1016/j.physbeh.2011.07.023. Epub 2011 Jul 30. Physiol Behav. 2011. PMID: 21827778
CRE/CREB-driven up-regulation of gene expression by chronic social stress in CRE-luciferase transgenic mice: reversal by antidepressant treatment.
Böer U, Alejel T, Beimesche S, Cierny I, Krause D, Knepel W, Flügge G. Böer U, et al. PLoS One. 2007 May 9;2(5):e431. doi: 10.1371/journal.pone.0000431. PLoS One. 2007. PMID: 17487276 Free PMC article.
In this transgene, luciferase enzyme activity and protein were detected throughout the brain, e.g., in the hippocampal formation. ...
In this transgene, luciferase enzyme activity and protein were detected throughout the brain, e.g., in the hippocampal formation. ...
Anhedonia and motivational deficits in rats: impact of chronic social stress.
Rygula R, Abumaria N, Flügge G, Fuchs E, Rüther E, Havemann-Reinecke U. Rygula R, et al. Behav Brain Res. 2005 Jul 1;162(1):127-34. doi: 10.1016/j.bbr.2005.03.009. Epub 2005 Apr 14. Behav Brain Res. 2005. PMID: 15922073
Citalopram counteracts depressive-like symptoms evoked by chronic social stress in rats.
Rygula R, Abumaria N, Flügge G, Hiemke C, Fuchs E, Rüther E, Havemann-Reinecke U. Rygula R, et al. Behav Pharmacol. 2006 Feb;17(1):19-29. doi: 10.1097/01.fbp.0000186631.53851.71. Behav Pharmacol. 2006. PMID: 16377960
Chronic social stress: effects on limbic brain structures.
Fuchs E, Flügge G. Fuchs E, et al. Physiol Behav. 2003 Aug;79(3):417-27. doi: 10.1016/s0031-9384(03)00161-6. Physiol Behav. 2003. PMID: 12954436 Review.
Common to the later multimodal stressors is that they need cortical processing and, depending on previous experience or ongoing activation, the information is assembled within limbic circuits connecting, e.g., the hippocampus, amygdala and prefrontal cortex to induce neuro …
Common to the later multimodal stressors is that they need cortical processing and, depending on previous experience or ongoing activation, …
Social stress in tree shrews: effects on physiology, brain function, and behavior of subordinate individuals.
Fuchs E, Flügge G. Fuchs E, et al. Pharmacol Biochem Behav. 2002 Aug;73(1):247-58. doi: 10.1016/s0091-3057(02)00795-5. Pharmacol Biochem Behav. 2002. PMID: 12076743 Review.
In addition to the changes in neurotransmitter systems, there are structural changes in neurons, e.g., retraction of the dendrites of hippocampal pyramidal neurons. ...
In addition to the changes in neurotransmitter systems, there are structural changes in neurons, e.g., retraction of the dendrites of …
Agomelatine in the tree shrew model of depression: effects on stress-induced nocturnal hyperthermia and hormonal status.
Schmelting B, Corbach-Söhle S, Kohlhause S, Schlumbohm C, Flügge G, Fuchs E. Schmelting B, et al. Eur Neuropsychopharmacol. 2014 Mar;24(3):437-47. doi: 10.1016/j.euroneuro.2013.07.010. Epub 2013 Aug 2. Eur Neuropsychopharmacol. 2014. PMID: 23978391
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