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A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.
Loutet SA, Flannagan RS, Kooi C, Sokol PA, Valvano MA. Loutet SA, et al. J Bacteriol. 2006 Mar;188(6):2073-80. doi: 10.1128/JB.188.6.2073-2080.2006. J Bacteriol. 2006. PMID: 16513737 Free PMC article.
Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo.
Flannagan RS, Aubert D, Kooi C, Sokol PA, Valvano MA. Flannagan RS, et al. Infect Immun. 2007 Apr;75(4):1679-89. doi: 10.1128/IAI.01581-06. Epub 2007 Jan 12. Infect Immun. 2007. PMID: 17220310 Free PMC article.
A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability.
Ortega XP, Cardona ST, Brown AR, Loutet SA, Flannagan RS, Campopiano DJ, Govan JR, Valvano MA. Ortega XP, et al. J Bacteriol. 2007 May;189(9):3639-44. doi: 10.1128/JB.00153-07. Epub 2007 Mar 2. J Bacteriol. 2007. PMID: 17337576 Free PMC article.
A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA. Aubert DF, et al. Infect Immun. 2008 May;76(5):1979-91. doi: 10.1128/IAI.01338-07. Epub 2008 Mar 3. Infect Immun. 2008. PMID: 18316384 Free PMC article.
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance.
Buroni S, Pasca MR, Flannagan RS, Bazzini S, Milano A, Bertani I, Venturi V, Valvano MA, Riccardi G. Buroni S, et al. BMC Microbiol. 2009 Sep 17;9:200. doi: 10.1186/1471-2180-9-200. BMC Microbiol. 2009. PMID: 19761586 Free PMC article.
Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42.
Flannagan RS, Jaumouillé V, Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Flannagan RS, et al. Cell Microbiol. 2012 Feb;14(2):239-54. doi: 10.1111/j.1462-5822.2011.01715.x. Epub 2011 Nov 15. Cell Microbiol. 2012. PMID: 22023324
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