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IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage.
Flannery CR, Little CB, Hughes CE, Curtis CL, Caterson B, Jones SA. Flannery CR, et al. Matrix Biol. 2000 Nov;19(6):549-53. doi: 10.1016/s0945-053x(00)00111-6. Matrix Biol. 2000. PMID: 11068209
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis.
Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, Flannery CR, Peluso D, Kanki K, Yang Z, Majumdar MK, Morris EA. Glasson SS, et al. Among authors: flannery cr. Nature. 2005 Mar 31;434(7033):644-8. doi: 10.1038/nature03369. Nature. 2005. PMID: 15800624
Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2).
Chockalingam PS, Zeng W, Morris EA, Flannery CR. Chockalingam PS, et al. Among authors: flannery cr. Arthritis Rheum. 2004 Sep;50(9):2839-48. doi: 10.1002/art.20496. Arthritis Rheum. 2004. PMID: 15457452
Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice.
Glasson SS, Askew R, Sheppard B, Carito BA, Blanchet T, Ma HL, Flannery CR, Kanki K, Wang E, Peluso D, Yang Z, Majumdar MK, Morris EA. Glasson SS, et al. Among authors: flannery cr. Arthritis Rheum. 2004 Aug;50(8):2547-58. doi: 10.1002/art.20558. Arthritis Rheum. 2004. PMID: 15334469
Autocatalytic cleavage of ADAMTS-4 (Aggrecanase-1) reveals multiple glycosaminoglycan-binding sites.
Flannery CR, Zeng W, Corcoran C, Collins-Racie LA, Chockalingam PS, Hebert T, Mackie SA, McDonagh T, Crawford TK, Tomkinson KN, LaVallie ER, Morris EA. Flannery CR, et al. J Biol Chem. 2002 Nov 8;277(45):42775-80. doi: 10.1074/jbc.M205309200. Epub 2002 Aug 28. J Biol Chem. 2002. PMID: 12202483
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage.
Collins-Racie LA, Flannery CR, Zeng W, Corcoran C, Annis-Freeman B, Agostino MJ, Arai M, DiBlasio-Smith E, Dorner AJ, Georgiadis KE, Jin M, Tan XY, Morris EA, LaVallie ER. Collins-Racie LA, et al. Among authors: flannery cr. Matrix Biol. 2004 Jul;23(4):219-30. doi: 10.1016/j.matbio.2004.05.004. Matrix Biol. 2004. PMID: 15296936
Binding and localization of recombinant lubricin to articular cartilage surfaces.
Jones AR, Gleghorn JP, Hughes CE, Fitz LJ, Zollner R, Wainwright SD, Caterson B, Morris EA, Bonassar LJ, Flannery CR. Jones AR, et al. Among authors: flannery cr. J Orthop Res. 2007 Mar;25(3):283-92. doi: 10.1002/jor.20325. J Orthop Res. 2007. PMID: 17106881
Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage.
Patel L, Sun W, Glasson SS, Morris EA, Flannery CR, Chockalingam PS. Patel L, et al. Among authors: flannery cr. BMC Musculoskelet Disord. 2011 Jul 15;12:164. doi: 10.1186/1471-2474-12-164. BMC Musculoskelet Disord. 2011. PMID: 21762512 Free PMC article.
Immunolocalisation and expression of proteoglycan 4 (cartilage superficial zone proteoglycan) in tendon.
Rees SG, Davies JR, Tudor D, Flannery CR, Hughes CE, Dent CM, Caterson B. Rees SG, et al. Among authors: flannery cr. Matrix Biol. 2002 Nov;21(7):593-602. doi: 10.1016/s0945-053x(02)00056-2. Matrix Biol. 2002. PMID: 12475643
Effects of n-3 fatty acids on cartilage metabolism.
Curtis CL, Rees SG, Cramp J, Flannery CR, Hughes CE, Little CB, Williams R, Wilson C, Dent CM, Harwood JL, Caterson B. Curtis CL, et al. Among authors: flannery cr. Proc Nutr Soc. 2002 Aug;61(3):381-9. doi: 10.1079/PNS2002174. Proc Nutr Soc. 2002. PMID: 12230798 Retracted.
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