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A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.
Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Mertens RT, et al. Among authors: flavell ra. Immunity. 2024 Sep 10;57(9):2077-2094.e12. doi: 10.1016/j.immuni.2024.06.001. Epub 2024 Jun 20. Immunity. 2024. PMID: 38906145 Free article.
The history and promise of Treg cells.
Benoist C, Vignali DAA, Flavell RA, Mathis D. Benoist C, et al. Among authors: flavell ra. Immunity. 2025 Dec 9;58(12):2934-2939. doi: 10.1016/j.immuni.2025.11.011. Immunity. 2025. PMID: 41371212 Review.
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection.
Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G. Torcellan T, et al. Among authors: flavell ra. Immunity. 2024 Jan 9;57(1):124-140.e7. doi: 10.1016/j.immuni.2023.11.018. Epub 2023 Dec 28. Immunity. 2024. PMID: 38157853 Free PMC article.
Genomics, genetics, and genes of the immune system.
Staudt LM, Flavell RA. Staudt LM, et al. Among authors: flavell ra. Immunity. 2001 Sep;15(3):335-6. doi: 10.1016/s1074-7613(01)00204-7. Immunity. 2001. PMID: 11567624 Free article. No abstract available.
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing.
Hartweger H, Ruprecht C, Yao KH, Laffont P, Lima Dos Reis G, Zhou P, Hägglöf T, Binet L, Loewe M, Hong JP, Xiao T, Sefik E, Hernandez B, Gazumyan A, Jankovic M, Seaman MS, Costa G, Nelson SA, Clark J, Kanatani S, Wilson PC, Krammer F, Levashina EA, Julien JP, Wardemann H, Sinnis P, Stamatatos L, Flavell RA, Nussenzweig MC. Hartweger H, et al. Among authors: flavell ra. bioRxiv [Preprint]. 2026 Jan 18:2026.01.16.699998. doi: 10.64898/2026.01.16.699998. bioRxiv. 2026. PMID: 41648379 Free PMC article. Preprint.
T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B.
Johnson JE, Agrawal K, Al-Lamki RS, Zhang F, Wang XD, Tobiasova Z, Taleb SA, Liburd S Jr, Rodriguez L, Martins AJ, Flavell RA, Robert ME, Sefik E, Pober JS. Johnson JE, et al. Among authors: flavell ra. Proc Natl Acad Sci U S A. 2026 Feb 10;123(6):e2525433123. doi: 10.1073/pnas.2525433123. Epub 2026 Feb 5. Proc Natl Acad Sci U S A. 2026. PMID: 41642982
Murine Bilateral Renal Lymphadenectomy.
Blackburn HN, Al Souz J, Lau SF, Craft J, Flavell RA. Blackburn HN, et al. Among authors: flavell ra. J Vis Exp. 2025 Dec 30;(226). doi: 10.3791/68695. J Vis Exp. 2025. PMID: 41554026
1,240 results