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PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer.
Kok M, Zwart W, Holm C, Fles R, Hauptmann M, Van't Veer LJ, Wessels LF, Neefjes J, Stål O, Linn SC, Landberg G, Michalides R. Kok M, et al. Among authors: fles r. Breast Cancer Res Treat. 2011 Jan;125(1):1-12. doi: 10.1007/s10549-010-0798-y. Epub 2010 Mar 9. Breast Cancer Res Treat. 2011. PMID: 20213082 Clinical Trial.
Estrogen receptor α wields treatment-specific enhancers between morphologically similar endometrial tumors.
Droog M, Nevedomskaya E, Dackus GM, Fles R, Kim Y, Hollema H, Mourits MJ, Nederlof PM, van Boven HH, Linn SC, van Leeuwen FE, Wessels LF, Zwart W. Droog M, et al. Among authors: fles r. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1316-E1325. doi: 10.1073/pnas.1615233114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167798 Free PMC article.
Prognosis of uterine corpus cancer after tamoxifen treatment for breast cancer.
Hoogendoorn WE, Hollema H, van Boven HH, Bergman E, de Leeuw-Mantel G, Platteel I, Fles R, Nederlof PM, Mourits MJ, van Leeuwen FE; Comprehensive Cancer Centers TAMARISK-group. Hoogendoorn WE, et al. Among authors: fles r. Breast Cancer Res Treat. 2008 Nov;112(1):99-108. doi: 10.1007/s10549-007-9823-1. Epub 2007 Dec 7. Breast Cancer Res Treat. 2008. PMID: 18064567
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.
Lechner M, Schartinger VH, Steele CD, Nei WL, Ooft ML, Schreiber LM, Pipinikas CP, Chung GT, Chan YY, Wu F, To KF, Tsang CM, Pearce W, Morelli D, Philpott M, Masterson L, Nibhani R, Wells G, Bell CG, Koller J, Delecluse S, Yip YL, Liu J, Forde CT, Forster MD, Jay A, Dudás J, Krapp A, Wan S, Uprimny C, Sprung S, Haybaeck J, Fenton TR, Chester K, Thirlwell C, Royle G, Marafioti T, Gupta R, Indrasari SR, Herdini C, Slim MAM, Indrawati I, Sutton L, Fles R, Tan B, Yeong J, Jain A, Han S, Wang H, Loke KSH, He W, Xu R, Jin H, Cheng Z, Howard D, Hwang PH, Le QT, Tay JK, West RB, Tsao SW, Meyer T, Riechelmann H, Oppermann U, Delecluse HJ, Willems SM, Chua MLK, Busson P, Lo KW, Wollmann G, Pillay N, Vanhaesebroeck B, Lund VJ. Lechner M, et al. Among authors: fles r. Nat Commun. 2021 Jan 5;12(1):117. doi: 10.1038/s41467-020-20308-8. Nat Commun. 2021. PMID: 33402692 Free PMC article.
The Impact of the Overall Radiotherapy Time on Clinical Outcome of Patients with Nasopharyngeal Carcinoma; A Retrospective Study.
Stoker SD, Fles R, Herdini C, Rijntjes FJ, Tjokronagoro M, Dwidanarti SR, Sikorska K, Leemans CR, Schmidt MK, Al-Mamgani A, Wildeman MA, Haryana SM, Indrasari SR, Tan IB. Stoker SD, et al. Among authors: fles r. PLoS One. 2016 Mar 31;11(3):e0151899. doi: 10.1371/journal.pone.0151899. eCollection 2016. PLoS One. 2016. PMID: 27030990 Free PMC article.
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